Zobrazeno 1 - 10
of 1 178
pro vyhledávání: '"A. K. Olsen"'
Autor:
Thale K. Olsen, Jörg Otte, Shenglin Mei, Bethel Tesfai Embaie, Polina Kameneva, Huaitao Cheng, Teng Gao, Vasilios Zachariadis, Ioanna Tsea, Åsa Björklund, Emil Kryukov, Ziyi Hou, Anna Johansson, Erik Sundström, Tommy Martinsson, Susanne Fransson, Jakob Stenman, Shahrzad Shirazi Fard, John Inge Johnsen, Per Kogner, Igor Adameyko, Martin Enge, Peter V. Kharchenko, Ninib Baryawno
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Neuroblastoma (NB) is a heterogeneous embryonal malignancy and the deadliest tumor of infancy. It is a complex disease that can result in diverse clinical outcomes. In some children, tumors regress spontaneously. Others respond we
Externí odkaz:
https://doaj.org/article/1d5da37f62bb4e9c8494a94bf33d81b4
Autor:
Seung H. Jung, Laura K. Olsen, Krysten A. Jones, Raquel J. Moore, Sean W. Harshman, Candice N. Hatcher-Solis
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionRecognition memory, an essential component of cognitive health, can suffer from biological limitations of stress, aging, or neurodegenerative disease. Vagus nerve stimulation (VNS) is a neuromodulation therapy with the potential to improv
Externí odkaz:
https://doaj.org/article/434cd49f8e2747d694aeb4b26f953db3
Autor:
Digant Nayak, Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak, Eliza A. Ruben, Zongyang Lv, Patrick Sung, Robert Hromas, Guangrong Zheng, Daohong Zhou, Shaun K. Olsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Overexpression of BCL-xL and BCL-2 play key roles in tumorigenesis and cancer drug resistance. Advances in PROTAC technology facilitated recent development of the first BCL-xL/BCL-2 dual degrader, 753b, a VHL-based degrader with improved pot
Externí odkaz:
https://doaj.org/article/4bf39db45fce4580a5d76e6623bf229c
Autor:
Laura P. Svetkey, Gary G. Bennett, Benjamin Reese, Leonor Corsino, Sandro O. Pinheiro, Jonathan E. Fischer, Judy Seidenstein, Maren K. Olsen, Tyson Brown, Natalie Ezem, Evan Liu, Alesha Majors, Karen E. Steinhauser, Brandy H. Sullivan, Michelle van Ryn, Sarah M. Wilson, Hongqiu Yang, Kimberly S. Johnson
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionClinician implicit racial bias (IB) may lead to lower quality care and adverse health outcomes for Black patients. Educational efforts to train clinicians to mitigate IB vary widely and have insufficient evidence of impact. We developed a
Externí odkaz:
https://doaj.org/article/a8964314b88246fe8d18a1dd49209e95
Autor:
Yongchao Dou, Yuejia Liu, Xinpei Yi, Lindsey K. Olsen, Hongwen Zhu, Qiang Gao, Hu Zhou, Bing Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Shotgun proteomics is essential for protein identification and quantification in biomedical research, but protein isoform characterization is challenging due to the extensive number of peptides shared across proteins, hindering our understan
Externí odkaz:
https://doaj.org/article/fe13be1c22c340dd9a4efbac90a33ce0
Autor:
Mohammad Afsar, GuanQun Liu, Lijia Jia, Eliza A. Ruben, Digant Nayak, Zuberwasim Sayyad, Priscila dos Santos Bury, Kristin E. Cano, Anindita Nayak, Xiang Ru Zhao, Ankita Shukla, Patrick Sung, Elizabeth V. Wasmuth, Michaela U. Gack, Shaun K. Olsen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract ISG15 plays a crucial role in the innate immune response and has been well-studied due to its antiviral activity and regulation of signal transduction, apoptosis, and autophagy. ISG15 is a ubiquitin-like protein that is activated by an E1 en
Externí odkaz:
https://doaj.org/article/6fb3d47e396d433991865fc8007dfe89
Autor:
Kara L. Gavin, Emily J. Almeida, Corrine I. Voils, Melissa M. Crane, Ryan Shaw, William S. Yancy Jr., Jane Pendergast, Maren K. Olsen
Publikováno v:
Obesity Science & Practice, Vol 9, Iss 4, Pp 337-345 (2023)
Abstract Introduction Obtaining body weights remotely could improve feasibility of pragmatic trials. This investigation examined whether weights collected via cellular scale or electronic health record (EHR) correspond to gold standard in‐person st
Externí odkaz:
https://doaj.org/article/707c8b6f9e75408fa90673ad5db9ffce
Autor:
Mikolaj Zmudzinski, Wioletta Rut, Kamila Olech, Jarosław Granda, Mirosław Giurg, Małgorzata Burda-Grabowska, Rafał Kaleta, Michala Zgarbova, Renata Kasprzyk, Linlin Zhang, Xinyuanyuan Sun, Zongyang Lv, Digant Nayak, Malgorzata Kesik-Brodacka, Shaun K. Olsen, Jan Weber, Rolf Hilgenfeld, Jacek Jemielity, Marcin Drag
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against COVID-19. SARS-CoV-2 main protease (Mpro, 3CLpro) and papain-like protease (PLpro) are responsible for viral polyprotein cleavage—a process crucial for
Externí odkaz:
https://doaj.org/article/01362b97d3a24b76b811f51a8665c29d
Autor:
Frej Gammelgård, Jonas Nielsen, Emilia J. Nielsen, Malthe G. Hansen, Aage K. Olsen Alstrup, Juan O. Perea-García, Trine H. Jensen, Cino Pertoldi
Publikováno v:
Animals, Vol 14, Iss 12, p 1729 (2024)
This article applies object detection to CCTV video material to investigate the potential of using machine learning to automate behavior tracking. This study includes video tapings of two captive Bornean orangutans and their behavior. From a 2 min tr
Externí odkaz:
https://doaj.org/article/2608dc8e823e4b8e9454033bdfc3e7ca
Autor:
Jonas K Olsen, Troels Kristensen
Publikováno v:
BJGP Open, Vol 7, Iss 4 (2023)
Background: Continuity of care (COC) for older adults has been associated with lower use of healthcare services, decreased risk of hospitalisation, and lower mortality. However, research on COC in older adults is limited by short time periods and sma
Externí odkaz:
https://doaj.org/article/891ac259164840a3be876f88b16fa7b5