Zobrazeno 1 - 10
of 13
pro vyhledávání: '"A. K. M. Ghulam Muhammad"'
Autor:
Weidong Xiong, Marianela Candolfi, Chunyan Liu, A K M Ghulam Muhammad, Kader Yagiz, Mariana Puntel, Peter F Moore, Julie Avalos, John D Young, Dorothy Khan, Randy Donelson, G Elizabeth Pluhar, John R Ohlfest, Kolja Wawrowsky, Pedro R Lowenstein, Maria G Castro
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11074 (2010)
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and carries a dismal prognosis. We have developed a conditional cytotoxic/immunotherapeutic approach using adenoviral vectors (Ads) encoding the immunostimulatory cytokine
Externí odkaz:
https://doaj.org/article/7bbf55f8e7c44fb68695fec0b43c154f
Autor:
James F Curtin, Naiyou Liu, Marianela Candolfi, Weidong Xiong, Hikmat Assi, Kader Yagiz, Matthew R Edwards, Kathrin S Michelsen, Kurt M Kroeger, Chunyan Liu, A K M Ghulam Muhammad, Mary C Clark, Moshe Arditi, Begonya Comin-Anduix, Antoni Ribas, Pedro R Lowenstein, Maria G Castro
Publikováno v:
PLoS Medicine, Vol 6, Iss 1, p e10 (2009)
BackgroundGlioblastoma multiforme (GBM) is the most aggressive primary brain tumor that carries a 5-y survival rate of 5%. Attempts at eliciting a clinically relevant anti-GBM immune response in brain tumor patients have met with limited success, whi
Externí odkaz:
https://doaj.org/article/0adb0547db44421eb3369a03d288ff9a
Autor:
Toshihiko Isaka, A. K. M. Ghulam Muhammad, Motohiko Maruno, Toshiki Yoshimine, Kouichi Wada, Tsuyoshi Suzuki, Junji Taguchi
Publikováno v:
Brain Tumor Pathology. 23:65-70
The primary intracranial giant cell type of malignant fibrous histiocytoma (GC-MFH) is rare, and the resemblance to meningioma causes diagnostic confusion. Discrimination from meningioma bears important therapeutic and prognostic implications. We rep
Publikováno v:
Surgical Neurology. 54:458-463
BACKGROUND Removal of a thin but long foreign body lodged in the deep brain tissue may need special technique to remove it without causing major injury. We report a special technique for the safe, elective removal of such objects. CASE DESCRIPTION A
Autor:
Hirotomo Ninomiya, Hidemitsu Nakagawa, Toshihiko Isaka, Toshiki Yoshimine, A. K. M. Ghulam Muhammad, Motohiko Maruno, H. Nakata
Publikováno v:
Neurological Research. 22:181-184
Malignant gliomas encompassing the eloquent areas cannot be removed totally and their surgical extirpation is followed by adjuvant therapy for the residual tumor. Recently, we have employed fibrin glue as a vehicle for the sustained release of ACNU (
Autor:
Hidemitu Nakagawa, Motohiko Maruno, Amami Kato, A. K. M. Ghulam Muhammad, Toshiki Yoshimine, Toshihiko Isaka
Publikováno v:
Journal of Neuro-Oncology. 46:145-150
The ensuing ultrastructural changes in tumor vascular endothelial cells following intra-arterial administration of tumor necrosis factor-α (TNFα) were studied in an experimental rat glioma model. C6 glioma cells were implanted in Wistar rats and th
Autor:
A. K. M. Ghulam Muhammad, Toshiki Yoshimine, Amami Kato, Hirotomo Ninomiya, Motohiko Maruno, Toru Hayakawa
Publikováno v:
Cancer Letters. 135:61-66
We investigated chromosomal aberrations in 16 patients with astrocytic tumors of various histologic malignancies by comparative genomic hybridization (CGH). The degree of chromosomal loss was shown to be negatively correlated with histologic malignan
Autor:
Hirotomo Ninomiya, Eiji Kumura, Motohiko Maruno, Toshiki Yoshimine, A. K. M. Ghulam Muhammad, Amami Kato, Toru Hayakawa
Publikováno v:
Neuroscience Letters. 247:29-32
Previous investigators have localized the human glial fibrillary acidic protein (GFAP) gene in the segment 17q21 in chromosome 17. In the present study, we statistically assessed the association between the allelic status in thirty-three microsatelli
Autor:
Kurt M, Kroeger, A K M Ghulam, Muhammad, Gregory J, Baker, Hikmat, Assi, Mia K, Wibowo, Weidong, Xiong, Kader, Yagiz, Marianela, Candolfi, Pedro R, Lowenstein, Maria G, Castro
Publikováno v:
Discovery medicine. 10(53)
Glioblastoma multiforme (GBM) is a deadly primary brain tumor in adults, with a median survival of ~12-18 months post-diagnosis. Despite recent advances in conventional therapeutic approaches, only modest improvements in median survival have been ach
Autor:
Masayuki Hirata, Hirotomo Ninomiya, A. K. M. Ghulam Muhammad, Toshiki Yoshimine, Amami Kato, Motohiko Maruno
Publikováno v:
Scopus-Elsevier
Frozen sections of 35 astrocytic tumors of various histologic malignancies were analyzed by comparative genomic hybridization in an attempt to characterize the profile of genetic aberrations. Over 94% of the samples revealed DNA copy number aberratio