Zobrazeno 1 - 10
of 1 600
pro vyhledávání: '"A. K. Kelly"'
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 8, Iss 1, Pp 1-8 (2017)
Abstract Background When an animal is exposed to a stressor, metabolic rate, energy consumption and utilisation increase primarily through activation of the hypothalamic-pituitary-adrenal (HPA) axis. Changes to partitioning of energy by an animal are
Externí odkaz:
https://doaj.org/article/915914cd55684d89a9ca2e11a7d938e8
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Chromosomal inversions have been implicated in a remarkable range of natural phenomena, but it remains unclear how much they contribute to standing genetic variation. Here, we evaluate 64 inversions that segregate within a single natural pop
Externí odkaz:
https://doaj.org/article/1bb9d78de6074998a7a1fd3c7b79a690
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Enhanced nutrition during the early calfhood period has been shown to lead to earlier pubertal development in heifer calves. This is of interest as earlier pubertal onset can subsequently facilitate earlier calving which can econo
Externí odkaz:
https://doaj.org/article/68aed8c130e942f38438ab593cc16dac
Autor:
Nicole M. Naranjo, Anne Kennedy, Anna Testa, Cecilia E. Verrillo, Adrian D. Altieri, Rhonda Kean, D. Craig Hooper, Jindan Yu, Jonathan Zhao, Oliver Abinader, Maxwell W. Pickles, Adam Hawkins, William K. Kelly, Ramkrishna Mitra, Lucia R. Languino
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Prostate cancer has heterogeneous growth patterns, and its prognosis is the poorest when it progresses to a neuroendocrine phenotype. Using bioinformatic analysis, we evaluated RNA expression of neuroendocrine genes in a panel of five different cance
Externí odkaz:
https://doaj.org/article/cc3eebc16b874208b219a26ee873f2eb
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPrimary human neutrophils play a pivotal role in innate immunity, mainly through the formation of neutrophil extracellular traps (NETs) in a process known as NETosis. This cell-death pathway is crucial for combating infections but is also i
Externí odkaz:
https://doaj.org/article/9c5ad7f3503a47aba7c90808dd3f1d17
Autor:
Cecilia E. Verrillo, Fabio Quaglia, Christopher D. Shields, Stephen Lin, Andrew V. Kossenkov, Hsin‐Yao Tang, David Speicher, Nicole M. Naranjo, Anna Testa, William K. Kelly, Qin Liu, Benjamin Leiby, Luca Musante, Khalid Sossey‐Alaoui, Navneet Dogra, Tzu‐Yi Chen, Dario C. Altieri, Lucia R. Languino
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract It is known that small extracellular vesicles (sEVs) are released from cancer cells and contribute to cancer progression via crosstalk with recipient cells. We have previously reported that sEVs expressing the αVβ3 integrin, a protein upre
Externí odkaz:
https://doaj.org/article/04359d9772ad413f94e97e0367c5aad3
Autor:
Sharifu K. Tusuubira, John K. Kelly
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Ecological and evolutionary changes are likely to occur rapidly when outcrossing populations experience pollinator loss. However, the number and identify of plant traits that will respond to this form of selection, as well as the overall predictabili
Externí odkaz:
https://doaj.org/article/35870e01c841450fa1b8e24b4f5259b9
Autor:
Paris Veltsos, John K Kelly
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011072 (2024)
Gene expression can be influenced by genetic variants that are closely linked to the expressed gene (cis eQTLs) and variants in other parts of the genome (trans eQTLs). We created a multiparental mapping population by sampling genotypes from a single
Externí odkaz:
https://doaj.org/article/957b440c6c0746679d2af48322d294c3
Autor:
Josefina Orliacq, Aurora Pérez-Cornago, Siôn A Parry, Rebecca K Kelly, Dimitrios A Koutoukidis, Jennifer L Carter
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background and aims Excess energy intake can lead to metabolic dysfunction-associated steatotic liver disease (MASLD), but the relationship between dietary carbohydrate intake and liver fat content remains unclear. This study aimed to examin
Externí odkaz:
https://doaj.org/article/c164be588ac84d6c9179390670ef62d5