Zobrazeno 1 - 10
of 2 211
pro vyhledávání: '"A. K. Hoffmann"'
Autor:
Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles they are involved in
Externí odkaz:
https://doaj.org/article/8febd94011434cd39ad0e08df9476fce
Autor:
Linda Hofmann, Robin Lochbaum, Lutz Schütt, Ralph Röth, Stefanie Schmitteckert, Barbara Wollenberg, Thomas K. Hoffmann, Cornelia Brunner, Jens Greve, Janina Hahn, Marie-Nicole Theodoraki
Publikováno v:
Extracellular Vesicle, Vol 4, Iss , Pp 100056- (2024)
Hereditary angioedema (HAE) is an inherited disorder causing attacks of subcutaneous tissue or mucosa swelling. The disease burden and attack frequencies vary significantly among patients. This is the first pilot study investigating small extracellul
Externí odkaz:
https://doaj.org/article/fc12d7d63aff47c3b362a8a9b8ac4f46
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Background Hereditary angioedema with normal C1-inhibitor (HAE-nC1-INH) is a rare genetic disease. The symptoms can resemble other forms of hereditary angioedema (HAE), but the specific laboratory values are inconspicuous. The knowledge about treatme
Externí odkaz:
https://doaj.org/article/752857e1055a48539a0ceb361b231f64
Autor:
Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influenc
Externí odkaz:
https://doaj.org/article/00d90afcd16e4cecbcf18e983b6db96a
Autor:
Adrian Fehn, Adrian von Witzleben, Ayla Grages, Tsima Abou Kors, Jasmin Ezić, Annika C. Betzler, Cornelia Brunner, Patrick J. Schuler, Marie-Nicole Theodoraki, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101086- (2025)
Failure of immunotherapy in head and neck squamous cell carcinoma (HNSCC) patients represents an unmet need to augment leverage of adaptive immunity. Immunogenic cancer-testis antigen (CTA) expression as well as lymphocyte differentiation and functio
Externí odkaz:
https://doaj.org/article/f1c3848449674bbf8820fe8021af9d84
Publikováno v:
Ecology and Evolution, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Oysters are ecosystem engineering species building reef‐like biogenic structures in temperate shallow water environments, serving as biodiversity hotspots. Recently, also their ecosystem services such as fish nursery, pollutants sink and s
Externí odkaz:
https://doaj.org/article/022607e3a5954c5aab671809d51c9347
Autor:
Tsima Abou Kors, Matthias Meier, Lena Mühlenbruch, Annika C. Betzler, Franziska Oliveri, Martin Bens, Jaya Thomas, Johann M. Kraus, Johannes Doescher, Adrian von Witzleben, Linda Hofmann, Jasmin Ezic, Diana Huber, Julian Benckendorff, Thomas F. E. Barth, Jens Greve, Patrick J. Schuler, Cornelia Brunner, Jonathan M. Blackburn, Thomas K. Hoffmann, Christian Ottensmeier, Hans A. Kestler, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis antigens (CTA)
Externí odkaz:
https://doaj.org/article/395296b0c62b42a7af04bb14da175331
Autor:
Julius M. Vahl, Gabriele Nagel, Tsima Abou Kors, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Ayla Grages, Marie N. Theodoraki, Jens Greve, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Stephan Stilgenbauer, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21426-21435 (2023)
Abstract Introduction Demographics are important prognostic factors in malignant diseases. A nationwide analysis concerning the prognostic impact of demographics in head and neck cancer (HNC) patients (HNCP) has not been performed previously. Methods
Externí odkaz:
https://doaj.org/article/403267fe0932404bb41475658f084ee6
Autor:
Julius M. Vahl, Gabriele Nagel, Ayla Grages, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Marie‐Nicole Theodoraki, Jens Greve, Tsima Aboukors, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18826-18836 (2023)
Abstract Background Demographic development in rural and urban areas differs substantially. Demographics and access to specialized head and neck cancer centers may affect head and neck cancer patients' (HNCP) outcomes. Here, we compare epidemiologica
Externí odkaz:
https://doaj.org/article/a1465fdd240b4ed1b704c84412fc0dbc
Autor:
Lisa T. Huber, Johann M. Kraus, Jasmin Ezić, Amin Wanli, Marco Groth, Simon Laban, Thomas K. Hoffmann, Barbara Wollenberg, Hans A. Kestler, Cornelia Brunner
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 422-446 (2023)
Aim: Recently, a tumor cell-platelet interaction was identified in different tumor entities, resulting in a transfer of tumor-derived RNA into platelets, named further “tumor-educated platelets (TEP)”. The present pilot study aims to investigate
Externí odkaz:
https://doaj.org/article/7f08bddc60874ffa92d65bc1ddf7441a