Zobrazeno 1 - 5
of 5
pro vyhledávání: '"A. K. Grehova"'
Autor:
L. A. Ostrovskaya, D. B. Korman, A. K. Grehova, V. A. Rikova, N. V. Bluhterova, K. A. Abzaeva, M. M. Fomina
Publikováno v:
Russian Journal of Physical Chemistry B. 13:956-963
The results of preclinical study of the original antitumor drug aurumacryl (gold polyacrylate), which belongs to polyacrylates of metals (PAMs), a new class of compounds for use in oncology, are presented. PAMs have been studied as cytostatics for th
Autor:
V. Brunchukov, Yu. Fedotov, Andrey Bushmanov, Tatyana Alexeevna Astrelina, A. K. Grehova, A.S. Samoylov, Margarita Pustovalova, A. A. Tsishnatti, Andreyan N. Osipov, Victoria Nikitina, D. Usupzhanova, T. Blohina, I. Kobzeva, N. Vorob'eva, I. Barabash
Publikováno v:
Medical Radiology and radiation safety. :5-10
Purpose: To conduct a comparative assessment of the effect of irradiation of human mesenchymal stem cells (MSC)at ultrahigh doses at liquid nitrogen temperature (–196 °C) and room temperature (+22 °C) on the yield of “residual” DNA double-str
Autor:
T. Blohina, Victoria Nikitina, O. A. Kochetkov, E. Suchkova, D I Kabanov, N. Vorob'eva, V. Uyba, Andreyan N. Osipov, E. I. Yashkina, I. Kobzeva, A. K. Grehova, T. Astrelina, Margarita Pustovalova
Publikováno v:
Medical Radiology and radiation safety. 63:28-34
Purpose: To estimate the impact of 3H-thymidine on DNA double strand breaks (DSBs) induction in cultured human mesenchymal stem cells (MSC). Material and methods: Isolation and cultivation of human bone marrow MSC was carried out according to a stand
Autor:
K. A. Abzaeva, N. V. Bluhterova, L. A. Ostrovskaya, D. B. Korman, Andreyan N. Osipov, V. A. Rikova, M. M. Fomina, A. K. Grehova
Publikováno v:
Russian Chemical Bulletin. 66:2333-2338
Gold polyacrylate (aurumacryl) belonging to a new class of compounds for oncology — metal polyacrylates — was shown to exhibit strong antitumor activity. Aurumacryl causes 80—90% growth inhibition in vivo of murine solid tumors (Lewis lung carc
Autor:
Andreyan N. Osipov, V. A. Rikova, L. A. Ostrovskaya, N. V. Bluhterova, D. B. Korman, A. K. Grehova, K. A. Abzaeva, M. M. Fomina
Publikováno v:
Biophysics. 62:485-489
The cellular effects of aurumacryl (a drug based on gold polyacrylate, which previously showed significant antitumor activity in vivo against solid tumors in mice) were studied in the model of the MCF7 stable cell line of human breast carcinoma. It w