Impact of Combined Subthalamic Nucleus and Substantia Nigra Stimulation on Neuropsychiatric Symptoms in Parkinson’s Disease Patients

Autor: U. Hidding, A. Gulberti, A. Horn, C. Buhmann, W. Hamel, J. A. Koeppen, M. Westphal, A. K. Engel, C. Gerloff, D. Weiss, C. K. E. Moll, M. Pötter-Nerger

Publikováno v: Parkinson's Disease, Vol 2017 (2017)

The goal of the study was to compare the tolerability and the effects of conventional subthalamic nucleus (STN) and combined subthalamic nucleus and substantia nigra (STN+SNr) high-frequency stimulation in regard to neuropsychiatric symptoms in Parki

Externí odkaz: https://doaj.org/article/396f5834082b408d8f44c3ac9e718648

Premotor cortical beta synchronization and the network neuromodulation of externally paced finger tapping in Parkinson's disease

Autor: Alessandro Gulberti, Till R. Schneider, Edgar E. Galindo-Leon, Miriam Heise, Alessandro Pino, Manfred Westphal, Wolfgang Hamel, Carsten Buhmann, Simone Zittel, Christian Gerloff, Monika Pötter-Nerger, Andreas K. Engel, Christian K.E. Moll

Publikováno v: Neurobiology of Disease, Vol 197, Iss , Pp 106529- (2024)

Parkinson's disease (PD) is characterized by the disruption of repetitive, concurrent and sequential motor actions due to compromised timing-functions principally located in cortex-basal ganglia (BG) circuits. Increasing evidence suggests that motor

Externí odkaz: https://doaj.org/article/eeae681c6e4e4e2dab3dcacbf88ba1cb

Observation of the Galactic Center PeVatron beyond 100 TeV with HAWC

Autor: A. Albert, R. Alfaro, C. Alvarez, A. Andrés, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K. S. Caballero-Mora, T. Capistrán, A. Carramiñana, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, C. de León, D. Depaoli, N. Di Lalla, R. Diaz Hernandez, B. L. Dingus, M. A. DuVernois, J. C. Díaz-Vélez, K. Engel, T. Ergin, C. Espinoza, K. L. Fan, K. Fang, N. Fraija, S. Fraija, J. A. García-González, F. Garfias, H. Goksu, M. M. González, J. A. Goodman, S. Groetsch, J. P. Harding, S. Hernández-Cadena, I. Herzog, J. Hinton, D. Huang, F. Hueyotl-Zahuantitla, T. B. Humensky, P. Hüntemeyer, A. Iriarte, S. Kaufmann, D. Kieda, A. Lara, W. H. Lee, J. Lee, H. León Vargas, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, J. Martínez-Castro, J. A. Matthews, P. Miranda-Romagnoli, J. A. Montes, J. A. Morales-Soto, E. Moreno, M. Mostafá, M. Najafi, L. Nellen, M. Newbold, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, M. Osorio-Archila, Y. Pérez Araujo, E. G. Pérez-Pérez, C. D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, G. Schwefer, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, X. Wang, Z. Wang, I. J. Watson, E. Willox, H. Wu, S. Yu, S. Yun-Cárcamo, H. Zhou

Publikováno v: The Astrophysical Journal Letters, Vol 973, Iss 1, p L34 (2024)

We report an observation of ultrahigh-energy (UHE) gamma rays from the Galactic center (GC) region, using 7 yr of data collected by the High-Altitude Water Cherenkov (HAWC) Observatory. The HAWC data are best described as a point-like source (HAWC J1

Externí odkaz: https://doaj.org/article/53e13912cdd44427819dbc3770cab3dd

Leading and following: Noise differently affects semantic and acoustic processing during naturalistic speech comprehension

Autor: Xinmiao Zhang, Jiawei Li, Zhuoran Li, Bo Hong, Tongxiang Diao, Xin Ma, Guido Nolte, Andreas K. Engel, Dan Zhang

Publikováno v: NeuroImage, Vol 282, Iss , Pp 120404- (2023)

Despite the distortion of speech signals caused by unavoidable noise in daily life, our ability to comprehend speech in noisy environments is relatively stable. However, the neural mechanisms underlying reliable speech-in-noise comprehension remain t

Externí odkaz: https://doaj.org/article/59680215a6d24c5ba273eefb5623481e

ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning

Autor: Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

In mice, reactivation of neurons that express cFos during fear conditioning induces a behavioural response. Here the authors show that cFos expression in mouse dentate gyrus shifts every day to different neurons, even during highly consistent spatial

Externí odkaz: https://doaj.org/article/3533e982510d493eb9e861a533fcd010