Zobrazeno 1 - 10
of 16
pro vyhledávání: '"A. K. Claiborne"'
Autor:
Irma T. Ugalde, Mary K. Claiborne, Marylou Cardenas-Turanzas, Manish N. Shah, James R. Langabeer II, Rajan Patel
Publikováno v:
Western Journal of Emergency Medicine, Vol 19, Iss 6 (2018)
Introduction: Computed tomography angiography (CTA) is used to screen patients for cerebrovascular injury after blunt trauma, but risk factors are not clearly defined in children. This modality has inherent radiation exposure. We set out to better de
Externí odkaz:
https://doaj.org/article/f51afc2e2f084fdf8304a14fd8c4b1a0
Publikováno v:
Biophysical Journal. 112:305a
Publikováno v:
Biophysical Journal. 110:170a
Dielectric spectroscopy has been established as a standard technique to study the interaction of electromagnetic waves with biological materials such as tissues and cells. In this work, we developed a MATLAB program to simulate the dielectric dispers
Autor:
D. T. W. Chu, A. K. Claiborne
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 24
A series of quinoline and naphthyridine antibacterial agents possessing an acyclic or cyclic gem-disubstituted piperazine substituent at the C-7 position have been prepared and evaluated in vitro a...
Publikováno v:
Canadian Journal of Chemistry. 70:1323-1327
An alternative synthesis of (±)-7-(3-methylpiperazin-1-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrochloride 4, a potent antibacterial agent, was developed. The method was characterized by regiospecific displ
Publikováno v:
Canadian Journal of Chemistry. 70:1328-1337
A series of quinoline and naphthyridine antibacterial agents possessing an acyclic or cyclic gem-disubstituted piperazine substituent at the C-7 position have been prepared and evaluated in vitro and in vivo for antibacterial activity against a varie
Autor:
Deanne Crowell, Michael D. Tufano, Kennan C. Marsh, Kristine B. Berst, Jacob J. Plattner, Lisa A. Hasvold, Daniel T. W. Chu, Qun Li, Angela M. Nilius, Linus L. Shen, Weibo Wang, Kathleen Raye, Akiyo K. Claiborne, Jeff Alder, Robert K. Flamm
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(15)
The 8-position side chain of 2-pyridones is believed to be involved in the binding with bacterial DNA gyrase to form the ternary complex, making them very important for the activity of 2-pyridones. A series of 2-pyridones having fluoro-substituted am
Publikováno v:
Drugs under experimental and clinical research. 16(5)
Very little is known about the structure-activity relationship of quinolone antibacterials at the 2-position. Because of the loss of biological activity with 2-methyl and 2-hydroxyl substitution, modifications at C-2 were generally considered to be u