Zobrazeno 1 - 10
of 2 681
pro vyhledávání: '"A. Juillerat"'
Autor:
Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noemie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre Juillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau, Julien Valton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sickle cell disease is a devastating blood disorder that originates from a single point mutation in the HBB gene coding for hemoglobin. Here, we develop a GMP-compatible TALEN-mediated gene editing process enabling efficient HBB correction v
Externí odkaz:
https://doaj.org/article/a5ed07ba92514c729d823ca1c6aa5120
Autor:
Maria Feola, Sylvain Pulicani, Diane Tkach, Alex Boyne, Robert Hong, Louisa Mayer, Aymeric Duclert, Philippe Duchateau, Alexandre Juillerat
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract One of the most recent advances in the genome editing field has been the addition of “TALE Base Editors”, an innovative platform for cell therapy that relies on the deamination of cytidines within double strand DNA, leading to the format
Externí odkaz:
https://doaj.org/article/1c9ad18707b24a4ba4d27a874de706cd
Making use of covering systems and a theorem of D. Shiu, the first and second authors showed that for every positive integer $k$, there exist $k$ consecutive widely digitally delicate primes. They also noted that for every positive integer $k$, there
Externí odkaz:
http://arxiv.org/abs/2209.10646
Autor:
Dharani, Sonal, Cho, Hana, Fernandez, Jorge Postigo, Juillerat, Alexandre, Valton, Julien, Duchateau, Philippe, Poirot, Laurent, Das, Shipra
Publikováno v:
In Molecular Therapy 6 November 2024 32(11):3915-3931
Autor:
Andrea Kreienbuehl, Gerhard Rogler, Burri Emanuel, Luc Biedermann, Christian Meier, Pascal Juillerat, Sophie Restellini, Peter Hruz, Stefan R. Vavricka, Daniel Aeberli, Frank Seibold
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 6 (2024)
Patients with inflammatory bowel disease (IBD) are prone to reduced bone mineral density and elevated overall fracture risk. Osteopenia affects up to 40% of patients with IBD (high regional variability). Besides disease activity, IBD specialists must
Externí odkaz:
https://doaj.org/article/e62a86297c764765b3bb445ce1658d35
Autor:
Seclen, Eduardo, Jang, Jessica C., Lawal, Aminah O., Pulicani, Sylvain, Boyne, Alex, Tkach, Diane, Juillerat, Alexandre, Duchateau, Philippe, Valton, Julien
Publikováno v:
In Molecular Therapy 5 June 2024 32(6):1643-1657
Autor:
Filaseta, Michael, Juillerat, Jacob
We show that for every positive integer $k$, there exist $k$ consecutive primes having the property that if any digit of any one of the primes, including any of the infinitely many leading zero digits, is changed, then that prime becomes composite.
Externí odkaz:
http://arxiv.org/abs/2101.08898
Autor:
Poggi, Lucie, Chentout, Loïc, Lizot, Sabrina, Boyne, Alex, Juillerat, Alexandre, Moiani, Arianna, Luka, Marine, Carbone, Francesco, Ménager, Mickael, Cavazzana, Marina, Duchateau, Philippe, Valton, Julien, Kracker, Sven
Publikováno v:
In Molecular Therapy - Methods & Clinical Development 14 December 2023 31
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Autor:
Laura Rossier, Christoph Matter, Emanuel Burri, Tatiana Galperine, Petr Hrúz, Pascal Juillerat, Alain Schoepfer, Stephan R. Vavricka, Nadine Zahnd, Natalie Décosterd, Frank Seibold
Publikováno v:
Swiss Medical Weekly, Vol 153, Iss 8 (2023)
INTRODUCTION: Faecal microbiota transplantation (FMT) is an established therapy for recurrent C. difficile infection, and recent studies have reported encouraging results of FMT in patients with ulcerative colitis. Few international consensus guideli
Externí odkaz:
https://doaj.org/article/fbc8c4d5f8ca46a88768c2c1c5fd5072