Zobrazeno 1 - 10
of 371
pro vyhledávání: '"A. Jill Thompson"'
Autor:
Jack Swanson, Jason Tonne, Thanich Sangsuwannukul, Jill Thompson, Benjamin Kendall, Olivia Liseth, Muriel Metko, Richard Vile
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200873- (2024)
Chimeric antigen receptor (CAR) T cells are a clinically approved therapy for blood cancers. To produce clinical-grade CAR T cells, a retroviral or lentiviral vector is used to deliver the CAR and associated genes to patient T cells. Apolipoprotein B
Externí odkaz:
https://doaj.org/article/d31cc90c2f2343a696e8941748484f1a
Autor:
Mason J. Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Maria P. Chiriboga Yerovi, Michael Olin, Antonella Borgatti, Mark McNiven, Satdarshan P. S. Monga, Mitesh J. Borad, Alan Melcher, Lewis R. Roberts, Richard Vile
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Although patients benefit from immune checkpoint inhibition (ICI) therapy in a broad variety of tumors, resistance may arise from immune suppressive tumor microenvironments (TME), which is particularly true of hepatocellular carcinoma (HCC).
Externí odkaz:
https://doaj.org/article/3cf0fc38fa494b069051f0ff5e7872c6
Autor:
Jason M. Tonne, Karol Budzik, Talia Fernandez Carrasco, Landon Ebbert, Jill Thompson, Rebecca Nace, Benjamin Kendall, Rosa M. Diaz, Stephen J. Russell, Richard G. Vile
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200852- (2024)
Chimeric antigen receptor (CAR) T cells have had limited success against solid tumors. Here, we used an oncolytic foamy virus (oFV) to display a model CAR target antigen (CD19) on tumors in combination with anti-CD19 CAR T cells. We generated oFV-Δb
Externí odkaz:
https://doaj.org/article/32c9747a81a4467cac125fdb100cfb25
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
BackgroundOsteoarthritis causes chronic pain, impaired joint function, decreased mobility and negatively impacts quality of life (QOL). Anti-nerve growth factor antibodies bedinvetmab for dogs and frunevetmab for cats are licensed for the alleviation
Externí odkaz:
https://doaj.org/article/2884044326b94fb19be450d62f48b6ac
Autor:
Muriel Metko, Jason Tonne, Alexa Veliz Rios, Jill Thompson, Haley Mudrick, David Masopust, Rosa Maria Diaz, Michael A. Barry, Richard G. Vile
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1191 (2024)
Background: Long-lived, re-activatable immunity to SARS-CoV-2 and its emerging variants will rely on T cells recognizing conserved regions of viral proteins across strains. Heterologous prime–boost regimens can elicit elevated levels of circulating
Externí odkaz:
https://doaj.org/article/d98810f9d5c34f26ac87a699cbde1ffe
Autor:
Edwina Gildea, Emma Scales-Theobald, Jill Thompson, Alasdair Cook, Katie Forde, George Skingley, Sophie Lawrie, Nicola Williamson, Charlotte Panter
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionCanine osteoarthritis (OA) causes pain and mobility impairment. This can reduce dog quality of life (QoL), owner QoL and owners’ satisfaction with, and adherence to, treatments. No existing canine OA-specific instrument assesses all thr
Externí odkaz:
https://doaj.org/article/10883d3b5a654052b002e5ad5f089dc3
Autor:
Camille S. Delavaux, Joseph A. LaManna, Jonathan A. Myers, Richard P. Phillips, Salomón Aguilar, David Allen, Alfonso Alonso, Kristina J. Anderson-Teixeira, Matthew E. Baker, Jennifer L. Baltzer, Pulchérie Bissiengou, Mariana Bonfim, Norman A. Bourg, Warren Y. Brockelman, David F. R. P. Burslem, Li-Wan Chang, Yang Chen, Jyh-Min Chiang, Chengjin Chu, Keith Clay, Susan Cordell, Mary Cortese, Jan den Ouden, Christopher Dick, Sisira Ediriweera, Erle C. Ellis, Anna Feistner, Amy L. Freestone, Thomas Giambelluca, Christian P. Giardina, Gregory S. Gilbert, Fangliang He, Jan Holík, Robert W. Howe, Walter Huaraca Huasca, Stephen P. Hubbell, Faith Inman, Patrick A. Jansen, Daniel J. Johnson, Kamil Kral, Andrew J. Larson, Creighton M. Litton, James A. Lutz, Yadvinder Malhi, Krista McGuire, Sean M. McMahon, William J. McShea, Hervé Memiaghe, Anuttara Nathalang, Natalia Norden, Vojtech Novotny, Michael J. O’Brien, David A. Orwig, Rebecca Ostertag, Geoffrey G. (‘Jess’) Parker, Rolando Pérez, Glen Reynolds, Sabrina E. Russo, Lawren Sack, Pavel Šamonil, I-Fang Sun, Mark E. Swanson, Jill Thompson, Maria Uriarte, John Vandermeer, Xihua Wang, Ian Ware, George D. Weiblen, Amy Wolf, Shu-Hui Wu, Jess K. Zimmerman, Thomas Lauber, Daniel S. Maynard, Thomas W. Crowther, Colin Averill
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract One mechanism proposed to explain high species diversity in tropical systems is strong negative conspecific density dependence (CDD), which reduces recruitment of juveniles in proximity to conspecific adult plants. Although evidence shows th
Externí odkaz:
https://doaj.org/article/7ba04bd1933841d0a8cbeaa6b0743f6d
Autor:
Mason J. Webb, Timothy Kottke, Benjamin L. Kendall, Jack Swanson, Chisom Uzendu, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Mitesh Borad, Lewis Roberts, Rosa M. Diaz, Michael Olin, Antonella Borgatti, Richard Vile
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 129-142 (2023)
In multiple models of oncolytic virotherapy, it is common to see an early anti-tumor response followed by recurrence. We have previously shown that frontline treatment with oncolytic VSV-IFN-β induces APOBEC proteins, promoting the selection of spec
Externí odkaz:
https://doaj.org/article/7ab80cb6ce704e9f9a41cf0126c80a1b
Pediatric Injectable Drugs, also known as “The Teddy Bear Book,” is one of the ASHP's most recognized and trusted resources dedicated to helping pharmacists treat pediatric patients with injectable drugs. For more than 20 years, pharmacists and h
Publikováno v:
Insights into Imaging, Vol 13, Iss 1, Pp 1-33 (2022)
Abstract Children attending hospital for radiological procedures can experience uncertainty, anxiety and distress; this can result in sub-optimal experiences for children, poor scan quality and the need for radiological procedures to be rescheduled o
Externí odkaz:
https://doaj.org/article/dbcfead320b442f389d1f68470fce9c5