Zobrazeno 1 - 10
of 48
pro vyhledávání: '"A. Jennifer Rivett"'
Autor:
Ferry Ossendorp, Edwin Quinten, Nathalie Fu, Cornelis J. M. Melief, Natascha de Graaf, Alexander J. Pemberton, A. Jennifer Rivett, Selina Khan
Publikováno v:
Vaccine. 27:5252-5258
In our previous studies we have shown that bacterial enterotoxin B subunits are effective vehicles to deliver antigen into the MHC class I processing route. Here we have used the non-toxic Escherichia coli heat labile enterotoxin B subunit (EtxB) con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d424409c5df9d02c23d91f2393a655f
https://doi.org/10.1016/j.vaccine.2009.06.053
https://doi.org/10.1016/j.vaccine.2009.06.053
Autor:
José Javier Martín de Llano, A. Jennifer Rivett, Graciela Fuertes, Erwin Knecht, Adoración Villarroya
Publikováno v:
Biochemical Journal. 375:75-86
The contribution of the main proteolytic pathways to the degradation of long-lived proteins in human fibroblasts grown under different conditions was investigated. The effects of various commonly used pharmacological inhibitors of protein degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd273f2bcc01e1d2c1b0e224e6db717
https://doi.org/10.1042/bj20030282
https://doi.org/10.1042/bj20030282
Autor:
Paul Brooks, Katia Forti, Fiona L. L. Stratford, Alexander J. Pemberton, A. Jennifer Rivett, Suchira Bose, David Onion, David Shirley
Publikováno v:
Experimental Gerontology. 37:1217-1222
Proteasomes play a major role in intracellular protein turnover. They exist in cells in several different molecular forms including 20S proteasomes, 26S proteasomes and PA28-20S proteasome complexes. In this study we have compared the properties of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba3962f15070420a8704efe3662d646
https://doi.org/10.1016/s0531-5565(02)00127-4
https://doi.org/10.1016/s0531-5565(02)00127-4
Enhanced Delivery of Exogenous Peptides into the Class I Antigen Processing and Presentation Pathway
Publikováno v:
Infection and Immunity. 70:3249-3258
Current immunization strategies, using peptide or protein antigens, generally fail to elicit cytotoxic-T-lymphocyte responses, since these antigens are unable to access intracellular compartments where loading of major histocompatibility complex clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cb2304d6d9ef3b20783f7728d35646
https://doi.org/10.1128/iai.70.6.3249-3258.2002
https://doi.org/10.1128/iai.70.6.3249-3258.2002
Publikováno v:
Biochimie. 83:363-366
Proteasomes play a major role in non-lysosomal proteolysis and also in the processing of proteins for presentation by the MHC class I pathway. In animal cells they exist in several distinct molecular forms which contribute to the different functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b652055d13ba22c7e0c1d2c3ee9ea145
https://doi.org/10.1016/s0300-9084(01)01249-4
https://doi.org/10.1016/s0300-9084(01)01249-4
Autor:
A. Jennifer Rivett, Robert C. Gardner
Publikováno v:
Journal of Peptide Science. 6:478-488
Proteasomes are multicatalytic proteinase complexes which play a central role in intracellular protein degradation. They catalyse key events in cell cycle regulation and in the activation of the transcription factor NFκB. Proteasome inhibitors have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673cdd4517d2ce29f33e18011c7aee6b
https://doi.org/10.1002/1099-1387(200009)6:9<478::aid-psc285>3.0.co
https://doi.org/10.1002/1099-1387(200009)6:9<478::aid-psc285>3.0.co
Publikováno v:
Biochemical Journal. 332:315-320
The induction of apoptosis in thymocytes by the glucocorticoid dexamethasone was used as a model system to investigate whether there are changes in 20 S and 26 S proteasome activities during apoptosis. We observed that thymocytes contain high concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e376f43f2b99c9ad32e93c402a7d49
https://doi.org/10.1042/bj3320315
https://doi.org/10.1042/bj3320315
Autor:
Robert W. Spackman, Dietmar Steverding, Howard J. Royle, Alexander J. Pemberton, A. Jennifer Rivett
Publikováno v:
Planta Medica. 72:761-763
The natural compound tyropeptin A, a new peptidyl aldehyde proteasome inhibitor, was tested for its trypanocidal activity in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. The concentrations of tyropeptin A required to reduce th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f61d23edf07035729ca9416f651745
https://doi.org/10.1055/s-2006-931600
https://doi.org/10.1055/s-2006-931600
Publikováno v:
Journal of Biological Chemistry
20 and 26 S proteasomes were isolated from rat liver. The procedure developed for the 26 S proteasome resulted in greatly improved yields compared with previously published methods. A comparison of the kinetic properties of 20 and 26 S proteasomes sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbb49102ea61159e5fbf6d1fe3455e5
https://doi.org/10.1074/jbc.272.40.24899
https://doi.org/10.1074/jbc.272.40.24899
Autor:
Bertrand Friguet, Fiona L. L. Stratford, Niki Chondrogianni, Efstathios S. Gonos, A. Jennifer Rivett, Ioannis P. Trougakos
Publikováno v:
Free Radical Research 37 112-112
Normal human fibroblasts undergo a limited number of divisions in culture and progressively they reach a state of irreversible growth arrest, a process termed as replicative senescence. The proteasome is the major cellular proteolytic machinery, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9150b877e7a70b4f567fea7755a66640
http://helios-eie.ekt.gr/EIE/handle/10442/2971
http://helios-eie.ekt.gr/EIE/handle/10442/2971
