Surgical management of a laryngeal rhabdomyosarcoma in a cat

Autor: Akash Alexander, Katherine Hughes, Fernando Constantino-Casas, Laura Jane Owen

Publikováno v: Journal of Feline Medicine and Surgery Open Reports, Vol 9 (2023)

Case summary An 11-year-old male castrated British Shorthair was referred for investigations into an upper respiratory tract mass. A partial laryngectomy was performed to excise the mass. Marginal resection of the mass involved excision of parts of t

Externí odkaz: https://doaj.org/article/4f251b3d4507402f9bf552f2c168f679

Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties

Autor: Emma Pinder, Christopher J. Clemett, Craig R. Rice, Jane Harmer, P. Jane Owen-Lynch, Roger M. Phillips, Hollie B. S. Griffiths, Robert A. Faulkner, Heiko Wurdak, Jarosław Bryk, Michael L. Ginger, Simon J. Allison

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

One topical area of supramolecular chemistry is the binding of anionic species but despite the importance of anions in diverse cellular processes and for cancer development, anion receptors or ‘binders’ have received little attention as potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bd73459fbf77f419b8850047e7b6db
https://doaj.org/article/5894d27a002d445592149ac898aef1be

Live Twin Ectopic Pregnancy

Autor: Jen Heng Pek, Bret P. Nelson, Jane Owen, William L. Simpson

Publikováno v: The Journal of Emergency Medicine. 59:e77-e79

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa2f3b3d5813f54756cabd4a53ef011
https://doi.org/10.1016/j.jemermed.2020.04.033

PTU-138 Impact of new primary care faecal calprotectin (FCP) guidelines on secondary care workload and finance

Autor: Anet Soubieres, Frances Boa, Andrew Poullis, Taylor-Jane Owen

Publikováno v: Gastroenterology Service.

Introduction Faecal calprotectin (FCP) testing is a useful tool in the diagnostic work-up for differentiating Inflammatory Bowel Disease (IBD) from non-inflammatory bowel diseases. However, despite current support for its use, current guidelines lack

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a4d7754b529b379ef172bc24eba2305
https://doi.org/10.1136/gutjnl-2018-bsgabstracts.516

Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells

Autor: Robert A. Faulkner, Craig R. Rice, Owen J. Harper, Roger M. Phillips, David J. Cooke, Samantha L. Shepherd, Simon J. Allison, Richard T. Wheelhouse, Hollie B. S. Griffiths, Omar Khadeer Hussain, Paul I. P. Elliott, Francesca S. Davidson, P. Jane Owen-Lynch

Publikováno v: Allison, S J, Cooke, D, Davidson, F S, Elliott, P I P, Faulkner, R A, Griffiths, H B S, Harper, O, Hussain, O, Owen-Lynch, P J, Phillips, R M, Rice, C R, Shepherd, S L & Wheelhouse, R T 2018, ' Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells ', Angewandte Chemie-International Edition, vol. 57, no. 31, pp. 9799-9804 . https://doi.org/10.1002/anie.201805510

The ligands L1 and L2 both form separable dinuclear double-stranded helicate and mesocate complexes with RuII . In contrast to clinically approved platinates, the helicate isomer of [Ru2 (L1 )2 ]4+ was preferentially cytotoxic to isogenic cells (HCT1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e9edece6e9c1a660ee5a318687a30e
https://pubmed.ncbi.nlm.nih.gov/29863754