Zobrazeno 1 - 10
of 103
pro vyhledávání: '"A. James McKnight"'
Publikováno v:
In Journal of Magnetic Resonance July 2023 352
Publikováno v:
Magnetochemistry, Vol 9, Iss 1, p 33 (2023)
Protein methyl groups can participate in multiple motional modes on different time scales. Sub-nanosecond to nano-second time scale motions of methyl axes are particularly challenging to detect for small proteins in solutions. In this work we employ
Externí odkaz:
https://doaj.org/article/f94c805ab4b641e495120d4e21764be8
Publikováno v:
Journal of Magnetic Resonance. :107493
The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap.
Autor:
Jeffrey W Brown, Esther Bullitt, Sira Sriswasdi, Sandra Harper, David W Speicher, C James McKnight
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 6, p e1004302 (2015)
The primary, secondary, and tertiary structures of spectrin are reasonably well defined, but the structural basis for the known dramatic molecular shape change, whereby the molecular length can increase three-fold, is not understood. In this study, w
Externí odkaz:
https://doaj.org/article/17717d3439b84ccc83c61bfdf641edd4
Autor:
Deepak Raina, Praveen Agarwal, James Lee, Ajit Bharti, C James McKnight, Pankaj Sharma, Surender Kharbanda, Donald Kufe
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135156 (2015)
Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly expressed in diverse human carcinomas and certain hematologic malignancies. The oncogenic MUC1 transmembrane C-terminal subunit (MUC1-C) functions in part by transducing growth and survival
Externí odkaz:
https://doaj.org/article/58ce5746a4b044f088d440954949e217
Autor:
Haya Herscovitz, Arie Derksen, Mary T. Walsh, C. James McKnight, Donald L. Gantz, Margarita Hadzopoulou-Cladaras, Vassilis Zannis, Cynthia Curry, Donald M. Small
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 1, Pp 51-59 (2001)
The N-terminal 17% of apolipoprotein B (apoB-17) readily associates with dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles (MLV) to form large (240-Å diameter) discoidal particles. Because apoB is normally secreted with triacylglycerol (T
Externí odkaz:
https://doaj.org/article/569b49412d394a5fa1d7e918a03e0ce9
Autor:
Parker J. Nichols, Liliya Vugmeyster, Dmitry Ostrovsky, C. James McKnight, Beat Vögeli, Shibani Bhattacharya, Aaron Griffin
Publikováno v:
Journal of Biomolecular NMR. 72:39-54
We investigated correlated µs-ms time scale motions of neighboring 13C'-15N and 13Cα-13Cβ nuclei in both protonated and perdeuterated samples of GB3. The techniques employed, NMR relaxation due to cross-correlated chemical shift modulations, speci
Autor:
Jeffrey W Brown, C James McKnight
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9406 (2010)
Brush border microvilli are approximately 1-microm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells. A highly symmetric hexagonal array of thousands of these uniformly sized structure
Externí odkaz:
https://doaj.org/article/4cc5c71664c74e7da275de86964ea263
Autor:
George A. Mantiri, C. James McKnight, Amanda J. Hooper, John R. Burnett, A. David Marais, Sharon A. Miller, Donald M. Tanyanyiwa
Publikováno v:
Journal of Clinical Lipidology. 10:604-609
Background One genetic cause of markedly low plasma concentrations of apolipoprotein (apo) B and low density lipoprotein (LDL)-cholesterol is familial hypobetalipoproteinemia. Objective We aimed to determine the molecular basis for the marked hypocho
Autor:
Liliya, Vugmeyster, Aaron, Griffin, Dmitry, Ostrovsky, Shibani, Bhattacharya, Parker J, Nichols, C James, McKnight, Beat, Vögeli
Publikováno v:
Journal of biomolecular NMR. 72(1-2)
We investigated correlated μs-ms time scale motions of neighboring (13)C’─(15)N and (13)C(α)─(13)C(β) nuclei in both protonated and perdeuterated samples of GB3. The techniques employed, NMR relaxation due to cross-correlated chemical shift