Zobrazeno 1 - 10
of 112
pro vyhledávání: '"A. James Link"'
Autor:
Wen Kang Chou, Mathini Vaikunthan, Hendrik V. Schröder, A. James Link, Hahn Kim, Mark P. Brynildsen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Antibiotic resistance poses a serious threat to global health. To reinforce the anti-infective arsenal, many novel therapeutic strategies to fight bacterial infections are being explored. Among them, anti-virulence therapies, which target pathways im
Externí odkaz:
https://doaj.org/article/836565320a8d44f6b39a21eff98a15da
Publikováno v:
Microorganisms, Vol 10, Iss 2, p 358 (2022)
Flavohemoglobins, which are widely distributed in prokaryotes and eukaryotes, play key roles in oxygen (O2) transport and nitric oxide (·NO) defense. Hmp is the flavohemoglobin of Escherichia coli, and here we report that the translational fusion of
Externí odkaz:
https://doaj.org/article/721ccafb3bfb4efe8b16b4f4fdd1168c
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 702-709 (2016)
Externí odkaz:
https://doaj.org/article/0306b91882184a94bdcb34b5ba71f35e
Publikováno v:
ACS Central Science. 9:540-550
Publikováno v:
Biochemistry. 62:695-699
Autor:
Drew V. Carson, Monica Patiño, Hader E. Elashal, Alexis Jaramillo Cartagena, Yi Zhang, Megan E. Whitley, Larry So, Angelo K. Kayser-Browne, Ashlee M. Earl, Roby P. Bhattacharyya, A. James Link
Publikováno v:
ACS Infectious Diseases. 9:111-121
Publikováno v:
Journal of the American Chemical Society. 144:21628-21639
Several classes of ribosomally synthesized and post-translationally modified peptides (RiPPs) are composed of multiple macrocycles. The enzymes that assemble these macrocycles must surmount the challenge of installing a single specific set of linkage
Autor:
Sehmus Ozden, Susanna Monti, Valentina Tozzini, Nikita S. Dutta, Stefania Gili, Nick Caggiano, A. James Link, Nicola M. Pugno, John Higgins, Rodney D. Priestley, Craig B. Arnold
Publikováno v:
Materials Today. 59:46-55
Publikováno v:
ACS chemical biology. 17(8)
New antibiotics are needed as bacterial infections continue to be a leading cause of death, but efforts to develop compounds with promising antibacterial activity are hindered by a poor understanding of─and limited strategies for elucidating─thei
Autor:
Truc Do, A. James Link
Publikováno v:
Biochemistry.
Ribosomally synthesized and post-translationally modified peptides (RiPPs) make up a rapidly growing superfamily of natural products. RiPPs exhibit an extraordinary range of structures, but they all begin as gene-encoded precursor peptides that are l