Zobrazeno 1 - 10
of 45
pro vyhledávání: '"A. J. Witton"'
Publikováno v:
Education 3-13. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71110b338c2bf56b31477ce9422aa01
https://doi.org/10.1080/03004279.2022.2062022
https://doi.org/10.1080/03004279.2022.2062022
Autor:
Tove Kirkegaard, Timothy G. Cooke, F M Campbell, Joanne Edwards, John M. S. Bartlett, Linda Boye Jensen, Caroline J Witton, Kirsten Vang Nielsen
Publikováno v:
Histopathology. 56:203-211
Kirkegaard T, Witton C J, Edwards J, Nielsen K V, Jensen L B, Campbell F M, Cooke T G & Bartlett J M S (2010) Histopathology56, 203–211 Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH Aims: The AKT famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d719cab4b05db208435373d0cbcd2cea
https://doi.org/10.1111/j.1365-2559.2009.03467.x
https://doi.org/10.1111/j.1365-2559.2009.03467.x
Publikováno v:
British Journal of Cancer
Inactivating PTEN mutations are commonly found in prostate cancer, resulting in an increased activation of Akt. In this study, we investigate the role of PTEN deletion and protein expression in the development of hormone-refractory prostate cancer us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85f59aa1160e3c5533606ba5f60fd28
https://doi.org/10.1038/sj.bjc.6604680
https://doi.org/10.1038/sj.bjc.6604680
Publikováno v:
Forensic Science International. 167:30-42
This paper reports the results of an investigation to quantify variations in elemental concentrations amongst different particle size fractions obtained from a suite of sediment samples collected from the River Avon, UK. Concentrations of 49 elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e210965bff0e3fee2960dccc531a87
https://doi.org/10.1016/j.forsciint.2006.06.005
https://doi.org/10.1016/j.forsciint.2006.06.005
Autor:
Timothy G. Cooke, S. Tovey, John M. S. Bartlett, Caroline J Witton, Amanda Forsyth, Barbara Dunne
Publikováno v:
Clinical Cancer Research. 11:4835-4842
Purpose: Resistance to tamoxifen is linked to overexpression of HER2, and aromatase inhibitors show particular benefit in progesterone receptor (PR)–negative patients. We previously reported reduced survival in patients overexpressing HER1, HER2, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988718a8704adf477139d69af784bcb3
https://doi.org/10.1158/1078-0432.ccr-05-0196
https://doi.org/10.1158/1078-0432.ccr-05-0196
Autor:
T. G. Cooke, K V Nielsen, T Kirkegaard, L B Jensen, S. Brown, Sven Müller, Caroline J Witton, John M. S. Bartlett, F Campbell
Publikováno v:
Cancer biomarkers : section A of Disease markers. 5(1)
Uncontrolled growth of cancer cells can be related to dysfunctional cell cycle control, including entry into S-phase, initiating cell division. Cyclin CCND3 and CCNE1 along with CDK2 and CDK6 regulate this checkpoint, and genetic changes, detectable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ded7c3edd2f0ae28d2eb79a05737ab6
https://pubmed.ncbi.nlm.nih.gov/19242061
https://pubmed.ncbi.nlm.nih.gov/19242061
Publikováno v:
Breast Cancer Research
Introduction We have previously linked HER4 expression with increased survival in breast cancer. However, other reports have associated HER4 with adverse prognostic significance. One possible explanation for the conflicting reports may be that these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc290d37f044c4115468bcc22eaf4dc
https://doi.org/10.1186/bcr1394
https://doi.org/10.1186/bcr1394
Autor:
P J Carder, Philippa T. K. Saunders, Valerie Speirs, Peter A. Dervan, John M.S. Bartlett, Amanda McCann, Caroline J Witton, Rosemary A. Walker, M. Kennedy, Abeer M Shaaban, Christopher S. Foster, Claire E Murphy
Publikováno v:
Breast cancer research and treatment. 92(3)
Estrogen receptor (ER) alpha is a well-established independent prognostic factor in breast cancer whose presence determines the clinical implications of adjuvant endocrine therapy. A second receptor, ERb has been described, and a number of studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf6829d1ce54c9f11b419c19c3c487
https://pubmed.ncbi.nlm.nih.gov/16155800
https://pubmed.ncbi.nlm.nih.gov/16155800
Autor:
Barbara Dunne, Tove Kirkegaard, Caroline J Witton, John M. S. Bartlett, S. Tovey, Liane M. McGlynn, Alison Lyon
Publikováno v:
The Journal of pathology. 207(2)
Oestrogen receptor (ERalpha) expression is a strong predictor of response to endocrine therapy. The PI3K/AKT/mTOR signal transduction pathway has been implicated in endocrine resistance in vitro. The present study was carried out to test the hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c259d23120f2546abd3dfb1ca3cab
https://pubmed.ncbi.nlm.nih.gov/16088978
https://pubmed.ncbi.nlm.nih.gov/16088978
Publikováno v:
Histopathology. 45(1)
Aims: Inflammation and hormonal signalling induce cyclooxygenase 2 (COX2) expression in solid tumours. COX2 expression is linked to neovascularization and tumour growth. HER2 modulates colorectal cancer COX2 expression. We investigated interactions b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38bd95a11b34ded243549714863db5d
https://pubmed.ncbi.nlm.nih.gov/15228443
https://pubmed.ncbi.nlm.nih.gov/15228443