Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A. J. Tijsen"'
Publikováno v:
Journal of Patient Experience, Vol 10 (2023)
There is a trend toward formalization of the rehabilitation process for older rehabilitants in a Challenging Rehabilitation Environment (CRE). This concept involves the comprehensive organization of care, support, and environment in rehabilitation wa
Externí odkaz:
https://doaj.org/article/2d47fb66da954c6984236fac40c7b718
Autor:
Claire Hopton, Anke J. Tijsen, Leonid Maizels, Gil Arbel, Amira Gepstein, Nicola Bates, Benjamin Brown, Irit Huber, Susan J. Kimber, William G. Newman, Luigi Venetucci, Lior Gepstein
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Heterozygous missense variants of the cardiac ryanodine receptor gene (RYR2) cause catecholaminergic polymorphic ventricular tachycardia (CPVT). These missense variants of RYR2 result in a gain of function of the ryanodine receptors, charact
Externí odkaz:
https://doaj.org/article/0a54c9a572d34f8e990a65b6a055122d
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Circular RNAs (circRNAs) are a newly appreciated class of non-coding RNA molecules. Numerous tools have been developed for the detection of circRNAs, however computational tools to perform downstream functional analysis of circRNA
Externí odkaz:
https://doaj.org/article/00bec861443b4f159fb8e20b022269ec
Autor:
Anna M. D. Végh, Arie O. Verkerk, Lucía Cócera Ortega, Jianan Wang, Dirk Geerts, Mischa Klerk, Kirsten Lodder, Ruby Nobel, Anke J. Tijsen, Harsha D. Devalla, Vincent M. Christoffels, Max Medina-Ramírez, Anke M. Smits, Hanno L. Tan, Ronald Wilders, Marie José T. H. Goumans, Gerard J. J. Boink
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Electronic pacemakers still face major shortcomings that are largely intrinsic to their hardware-based design. Radical improvements can potentially be generated by gene or cell therapy-based biological pacemakers. Our previous work identified adenovi
Externí odkaz:
https://doaj.org/article/177579aa19c249d1bc638e48791bd6e1
Autor:
Lucía Cócera-Ortega, Ronald Wilders, Selina C. Kamps, Benedetta Fabrizi, Irit Huber, Ingeborg van der Made, Anouk van den Bout, Dylan K. de Vries, Lior Gepstein, Arie O. Verkerk, Yigal M. Pinto, Anke J. Tijsen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 4053 (2022)
Long-QT syndrome type 1 (LQT1) is caused by mutations in KCNQ1. Patients heterozygous for such a mutation co-assemble both mutant and wild-type KCNQ1-encoded subunits into tetrameric Kv7.1 potassium channels. Here, we investigated whether allele-spec
Externí odkaz:
https://doaj.org/article/ff87fa57dcd14cd09ff42369d3f65dbf
Publikováno v:
Journal of Clinical Medicine, 12
Journal of Clinical Medicine
Volume 12
Issue 3
Pages: 1231
Journal of Clinical Medicine, 12, 3
Journal of Clinical Medicine
Volume 12
Issue 3
Pages: 1231
Journal of Clinical Medicine, 12, 3
There is a trend towards the formalization of the rehabilitation process for older rehabilitants in a Challenging Rehabilitation Environment (CRE). This concept involves the comprehensive organization of care, support, and environment on rehabilitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf518a9f726d708cec929d66025022b2
http://hdl.handle.net/2066/290360
http://hdl.handle.net/2066/290360
Autor:
Rami Shinnawi, Irit Huber, Leonid Maizels, Naim Shaheen, Amira Gepstein, Gil Arbel, Anke J. Tijsen, Lior Gepstein
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 582-596 (2015)
The advent of the human-induced pluripotent stem cell (hiPSC) technology has transformed biomedical research, providing new tools for human disease modeling, drug development, and regenerative medicine. To fulfill its unique potential in the cardiova
Externí odkaz:
https://doaj.org/article/a4585caa049549da976fdd00d85ae58c
Autor:
Wino J Wijnen, Ingeborg van der Made, Stephanie van den Oever, Monika Hiller, Bouke A de Boer, Daisy I Picavet, Iliana A Chatzispyrou, Riekelt H Houtkooper, Anke J Tijsen, Jaco Hagoort, Henk van Veen, Vincent Everts, Jan M Ruijter, Yigal M Pinto, Esther E Creemers
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96290 (2014)
MicroRNAs (miRNAs) regulate many aspects of cellular function and their deregulation has been implicated in heart disease. MiRNA-30c is differentially expressed in the heart during the progression towards heart failure and in vitro studies hint to it
Externí odkaz:
https://doaj.org/article/39d74b6e26954e6f905a52655dac842b
Autor:
Lior Gepstein, Benjamin Brown, Claire Hopton, Irit Huber, Anke J. Tijsen, Arbel G, Susan J. Kimber, William G. Newman, Luigi Venetucci, Amira Gepstein, Bates N, L Maizels
BackgroundHeterozygous variants in the cardiac ryanodine receptor gene (RYR2) cause catecholaminergic polymorphic ventricular tachycardia (CPVT). Most pathogenic RYR2 variants are missense variants which result in a gain of function, causing ryanodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e349694e1774e5b4a93e0e741b7c179
https://doi.org/10.1101/2021.03.16.21252576
https://doi.org/10.1101/2021.03.16.21252576
Autor:
Lior Gepstein, Harsha D. Devalla, Yigal M. Pinto, Yolan J. Reckman, Anke J. Tijsen, Stefan Engelhardt, Simona Aufiero, Ingeborg van der Made, James S. Ware, Anouk van den Bout, Selina C. Kamps, Jiuru Li, Karin Y. van Spaendonck-Zwarts, Lucía Cócera Ortega, Xiaolei Zhang
Publikováno v:
Circulation, 143(15), 1502-1512. Lippincott Williams and Wilkins
Background: TTN (Titin), the largest protein in humans, forms the molecular spring that spans half of the sarcomere to provide passive elasticity to the cardiomyocyte. Mutations that disrupt the TTN transcript are the most frequent cause of hereditar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e1da8f005e0c41117a6dfebfdf546a
http://hdl.handle.net/10044/1/87316
http://hdl.handle.net/10044/1/87316