CellProfiler 4: improvements in speed, utility and usability

Autor: David R. Stirling, Madison J. Swain-Bowden, Alice M. Lucas, Anne E. Carpenter, Beth A. Cimini, Allen Goodman

Publikováno v: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-11 (2021)

Abstract Background Imaging data contains a substantial amount of information which can be difficult to evaluate by eye. With the expansion of high throughput microscopy methodologies producing increasingly large datasets, automated and objective ana

Externí odkaz: https://doaj.org/article/adfe542d663a452580ec88ea18afee91

Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease

Autor: Yuling Zhao, Matthew J. Haney, John K. Fallon, Myosotys Rodriguez, Carson J. Swain, Camryn J. Arzt, Philip C. Smith, Matthew Shane Loop, Emily B. Harrison, Nazira El-Hage, Elena V. Batrakova

Publikováno v: Cells, Vol 11, Iss 12, p 1933 (2022)

Extracellular vesicles (EVs) are cell-derived nanoparticles that facilitate transport of proteins, lipids, and genetic material, playing important roles in intracellular communication. They have remarkable potential as non-toxic and non-immunogenic n

Externí odkaz: https://doaj.org/article/f43b0e0e1cde45cda912a22132c1f305

Integrated intracellular organization and its variations in human iPS cells

Autor: Matheus P. Viana, Jianxu Chen, Theo A. Knijnenburg, Ritvik Vasan, Calysta Yan, Joy E. Arakaki, Matte Bailey, Ben Berry, Antoine Borensztejn, Eva M. Brown, Sara Carlson, Julie A. Cass, Basudev Chaudhuri, Kimberly R. Cordes Metzler, Mackenzie E. Coston, Zach J. Crabtree, Steve Davidson, Colette M. DeLizo, Shailja Dhaka, Stephanie Q. Dinh, Thao P. Do, Justin Domingus, Rory M. Donovan-Maiye, Alexandra J. Ferrante, Tyler J. Foster, Christopher L. Frick, Griffin Fujioka, Margaret A. Fuqua, Jamie L. Gehring, Kaytlyn A. Gerbin, Tanya Grancharova, Benjamin W. Gregor, Lisa J. Harrylock, Amanda Haupt, Melissa C. Hendershott, Caroline Hookway, Alan R. Horwitz, H. Christopher Hughes, Eric J. Isaac, Gregory R. Johnson, Brian Kim, Andrew N. Leonard, Winnie W. Leung, Jordan J. Lucas, Susan A. Ludmann, Blair M. Lyons, Haseeb Malik, Ryan McGregor, Gabe E. Medrash, Sean L. Meharry, Kevin Mitcham, Irina A. Mueller, Timothy L. Murphy-Stevens, Aditya Nath, Angelique M. Nelson, Sandra A. Oluoch, Luana Paleologu, T. Alexander Popiel, Megan M. Riel-Mehan, Brock Roberts, Lisa M. Schaefbauer, Magdalena Schwarzl, Jamie Sherman, Sylvain Slaton, M. Filip Sluzewski, Jacqueline E. Smith, Youngmee Sul, Madison J. Swain-Bowden, W. Joyce Tang, Derek J. Thirstrup, Daniel M. Toloudis, Andrew P. Tucker, Veronica Valencia, Winfried Wiegraebe, Thushara Wijeratna, Ruian Yang, Rebecca J. Zaunbrecher, Ramon Lorenzo D. Labitigan, Adrian L. Sanborn, Graham T. Johnson, Ruwanthi N. Gunawardane, Nathalie Gaudreault, Julie A. Theriot, Susanne M. Rafelski

Publikováno v: Nature. 613:345-354

Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours that they determine1,2. Here we reduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a684c7c821c5ce222400005b63258558
https://doi.org/10.1038/s41586-022-05563-7

Search for magnetic monopoles with the MoEDAL forward trapping detector in 2.11 fb−1 of 13 TeV proton–proton collisions at the LHC

Autor: B. Acharya, J. Alexandre, S. Baines, P. Benes, B. Bergmann, J. Bernabéu, A. Bevan, H. Branzas, M. Campbell, L. Caramete, S. Cecchini, M. de Montigny, A. De Roeck, J.R. Ellis, M. Fairbairn, D. Felea, M. Frank, D. Frekers, C. Garcia, J. Hays, A.M. Hirt, J. Janecek, D.-W. Kim, K. Kinoshita, A. Korzenev, D.H. Lacarrère, S.C. Lee, C. Leroy, G. Levi, A. Lionti, J. Mamuzic, A. Margiotta, N. Mauri, N.E. Mavromatos, P. Mermod, V.A. Mitsou, R. Orava, I. Ostrovskiy, B. Parker, L. Patrizii, G.E. Păvălaş, J.L. Pinfold, V. Popa, M. Pozzato, S. Pospisil, A. Rajantie, R. Ruiz de Austri, Z. Sahnoun, M. Sakellariadou, A. Santra, S. Sarkar, G. Semenoff, A. Shaa, G. Sirri, K. Sliwa, R. Soluk, M. Spurio, Y.N. Srivastava, M. Suk, J. Swain, M. Tenti, V. Togo, J.A. Tuszyński, V. Vento, O. Vives, Z. Vykydal, A. Widom, G. Willems, J.H. Yoon, I.S. Zgura

Publikováno v: Physics Letters B, Vol 782, Iss , Pp 510-516 (2018)

We update our previous search for trapped magnetic monopoles in LHC Run 2 using nearly six times more integrated luminosity and including additional models for the interpretation of the data. The MoEDAL forward trapping detector, comprising 222 kg of

Externí odkaz: https://doaj.org/article/59900f35be124f578b14ccedee993bba

Evidence for a mixed mass composition at the ‘ankle’ in the cosmic-ray spectrum

Autor: A. Aab, P. Abreu, M. Aglietta, E.J. Ahn, I. Al Samarai, I.F.M. Albuquerque, I. Allekotte, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, M. Ambrosio, G.A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, F. Arqueros, N. Arsene, H. Asorey, P. Assis, J. Aublin, G. Avila, A.M. Badescu, A. Balaceanu, C. Baus, J.J. Beatty, K.H. Becker, J.A. Bellido, C. Berat, M.E. Bertaina, P.L. Biermann, P. Billoir, J. Biteau, S.G. Blaess, A. Blanco, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, N. Borodai, A.M. Botti, J. Brack, I. Brancus, T. Bretz, A. Bridgeman, F.L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, K.S. Caballero-Mora, B. Caccianiga, L. Caccianiga, A. Cancio, F. Canfora, L. Caramete, R. Caruso, A. Castellina, G. Cataldi, L. Cazon, R. Cester, A.G. Chavez, A. Chiavassa, J.A. Chinellato, J. Chudoba, R.W. Clay, R. Colalillo, A. Coleman, L. Collica, M.R. Coluccia, R. Conceição, F. Contreras, M.J. Cooper, S. Coutu, C.E. Covault, J. Cronin, R. Dallier, S. D'Amico, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, R.M. de Almeida, S.J. de Jong, G. De Mauro, J.R.T. de Mello Neto, I. De Mitri, J. de Oliveira, V. de Souza, J. Debatin, L. del Peral, O. Deligny, C. Di Giulio, A. Di Matteo, M.L. Díaz Castro, F. Diogo, C. Dobrigkeit, J.C. D'Olivo, A. Dorofeev, R.C. dos Anjos, M.T. Dova, A. Dundovic, J. Ebr, R. Engel, M. Erdmann, M. Erfani, C.O. Escobar, J. Espadanal, A. Etchegoyen, H. Falcke, K. Fang, G. Farrar, A.C. Fauth, N. Fazzini, B. Fick, J.M. Figueira, A. Filevich, A. Filipčič, O. Fratu, M.M. Freire, T. Fujii, A. Fuster, B. García, D. Garcia-Pinto, F. Gaté, H. Gemmeke, A. Gherghel-Lascu, P.L. Ghia, U. Giaccari, M. Giammarchi, M. Giller, D. Głas, C. Glaser, H. Glass, G. Golup, M. Gómez Berisso, P.F. Gómez Vitale, N. González, B. Gookin, J. Gordon, A. Gorgi, P. Gorham, P. Gouffon, A.F. Grillo, T.D. Grubb, F. Guarino, G.P. Guedes, M.R. Hampel, P. Hansen, D. Harari, T.A. Harrison, J.L. Harton, Q. Hasankiadeh, A. Haungs, T. Hebbeker, D. Heck, P. Heimann, A.E. Herve, G.C. Hill, C. Hojvat, E. Holt, P. Homola, J.R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, J. Hulsman, A. Insolia, P.G. Isar, I. Jandt, S. Jansen, J.A. Johnsen, M. Josebachuili, A. Kääpä, O. Kambeitz, K.H. Kampert, P. Kasper, I. Katkov, B. Keilhauer, E. Kemp, R.M. Kieckhafer, H.O. Klages, M. Kleifges, J. Kleinfeller, R. Krause, N. Krohm, D. Kuempel, G. Kukec Mezek, N. Kunka, A. Kuotb Awad, D. LaHurd, L. Latronico, M. Lauscher, P. Lautridou, P. Lebrun, R. Legumina, M.A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, L. Lopes, R. López, A. López Casado, Q. Luce, A. Lucero, M. Malacari, M. Mallamaci, D. Mandat, P. Mantsch, A.G. Mariazzi, I.C. Mariş, G. Marsella, D. Martello, H. Martinez, O. Martínez Bravo, J.J. Masías Meza, H.J. Mathes, S. Mathys, J. Matthews, J.A.J. Matthews, G. Matthiae, E. Mayotte, P.O. Mazur, C. Medina, G. Medina-Tanco, D. Melo, A. Menshikov, S. Messina, M.I. Micheletti, L. Middendorf, I.A. Minaya, L. Miramonti, B. Mitrica, D. Mockler, L. Molina-Bueno, S. Mollerach, F. Montanet, C. Morello, M. Mostafá, G. Müller, M.A. Muller, S. Müller, I. Naranjo, S. Navas, L. Nellen, J. Neuser, P.H. Nguyen, M. Niculescu-Oglinzanu, M. Niechciol, L. Niemietz, T. Niggemann, D. Nitz, D. Nosek, V. Novotny, H. Nožka, L.A. Núñez, L. Ochilo, F. Oikonomou, A. Olinto, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, P. Papenbreer, G. Parente, A. Parra, T. Paul, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, L.A.S. Pereira, L. Perrone, C. Peters, S. Petrera, J. Phuntsok, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, C. Porowski, R.R. Prado, P. Privitera, M. Prouza, E.J. Quel, S. Querchfeld, S. Quinn, R. Ramos-Pollant, J. Rautenberg, O. Ravel, D. Ravignani, D. Reinert, B. Revenu, J. Ridky, M. Risse, P. Ristori, V. Rizi, W. Rodrigues de Carvalho, G. Rodriguez Fernandez, J. Rodriguez Rojo, M.D. Rodríguez-Frías, D. Rogozin, J. Rosado, M. Roth, E. Roulet, A.C. Rovero, S.J. Saffi, A. Saftoiu, H. Salazar, A. Saleh, F. Salesa Greus, G. Salina, J.D. Sanabria Gomez, F. Sánchez, P. Sanchez-Lucas, E.M. Santos, E. Santos, F. Sarazin, B. Sarkar, R. Sarmento, C. Sarmiento-Cano, R. Sato, C. Scarso, M. Schauer, V. Scherini, H. Schieler, D. Schmidt, O. Scholten, P. Schovánek, F.G. Schröder, A. Schulz, J. Schulz, J. Schumacher, S.J. Sciutto, A. Segreto, M. Settimo, A. Shadkam, R.C. Shellard, G. Sigl, G. Silli, O. Sima, A. Śmiałkowski, R. Šmída, G.R. Snow, P. Sommers, S. Sonntag, J. Sorokin, R. Squartini, D. Stanca, S. Stanič, J. Stasielak, F. Strafella, F. Suarez, M. Suarez Durán, T. Sudholz, T. Suomijärvi, A.D. Supanitsky, M.S. Sutherland, J. Swain, Z. Szadkowski, O.A. Taborda, A. Tapia, A. Tepe, V.M. Theodoro, C. Timmermans, C.J. Todero Peixoto, L. Tomankova, B. Tomé, A. Tonachini, G. Torralba Elipe, D. Torres Machado, M. Torri, P. Travnicek, M. Trini, R. Ulrich, M. Unger, M. Urban, A. Valbuena-Delgado, J.F. Valdés Galicia, I. Valiño, L. Valore, G. van Aar, P. van Bodegom, A.M. van den Berg, A. van Vliet, E. Varela, B. Vargas Cárdenas, G. Varner, J.R. Vázquez, R.A. Vázquez, D. Veberič, V. Verzi, J. Vicha, L. Villaseñor, S. Vorobiov, H. Wahlberg, O. Wainberg, D. Walz, A.A. Watson, M. Weber, A. Weindl, L. Wiencke, H. Wilczyński, T. Winchen, D. Wittkowski, B. Wundheiler, S. Wykes, L. Yang, D. Yelos, P. Younk, A. Yushkov, E. Zas, D. Zavrtanik, M. Zavrtanik, A. Zepeda, B. Zimmermann, M. Ziolkowski, Z. Zong, F. Zuccarello

Publikováno v: Physics Letters B, Vol 762, Iss , Pp 288-295 (2016)

We report a first measurement for ultrahigh energy cosmic rays of the correlation between the depth of shower maximum and the signal in the water Cherenkov stations of air-showers registered simultaneously by the fluorescence and the surface detector

Externí odkaz: https://doaj.org/article/178bf9fc316c404ba154c8a9881eb2d2