Zobrazeno 1 - 10
of 1 167
pro vyhledávání: '"A. J. Strong"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The progressive degeneration of motor neurons in amyotrophic lateral sclerosis (ALS) is accompanied by the formation of a broad array of cytoplasmic and nuclear neuronal inclusions (protein aggregates) largely containing RNA-binding proteins such as
Externí odkaz:
https://doaj.org/article/f05e58e2e4c44623952c03fca6ab3b68
Autor:
Erin Santandrea, Farhang Aliakbari, Emily Truscott, Lynda McCaig, Neil S. Donison, Danielle Graham, Michael J. Strong, Kathryn Volkening
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Ethical animal use follows the 3R’s: Replacement, Reduction and Refinement. Here, we present the use of simultaneous jugular vein and cisterna magna catheterization via a port system in rats for repeated fluid sampling for 14 consecutive d
Externí odkaz:
https://doaj.org/article/3a60acbbf2c14d86bd7a9e0e73227a25
Autor:
Joseph R. Linzey, Varun G. Kathawate, Michael J. Strong, Kayla Roche, Peyton E. Goethe, Lila R. Tudrick, Johan Lee, Arushi Tripathy, Sravanthi Koduri, Ayobami L. Ward, Oludotun Ogunsola, Mark M. Zaki, Rushikesh S. Joshi, Grant Weyburne, Charles S. Mayo, Joseph R. Evans, William C. Jackson, Nicholas J. Szerlip
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 20177-20187 (2023)
Abstract Background As cancer therapies have improved, spinal metastases are increasingly common. Resulting complications have a significant impact on patient's quality of life. Optimal methods of surveillance and avoidance of neurologic deficits are
Externí odkaz:
https://doaj.org/article/2dc5d62a929943719618737080a66a75
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 298 (2024)
Tuberculosis remains a significant global health pandemic. There is an urgent need for new anti-tubercular agents to combat the rising incidence of drug resistance and to offer effective and additive therapeutic options. High-throughput screening of
Externí odkaz:
https://doaj.org/article/90debecfbc8e405cb567616a62ee7621
Publikováno v:
Ecological Indicators, Vol 158, Iss , Pp 111360- (2024)
Productivity is a primary indicator when assessing plant communities or their responses to various stimuli, but it can be difficult and costly to determine. Adding to this complication is the retention of standing litter from previous years’ growth
Externí odkaz:
https://doaj.org/article/b5f16829ec12441e9fc992933f7e75d5
Publikováno v:
Non-Coding RNA, Vol 10, Iss 2, p 23 (2024)
Paraspeckles are nuclear condensates formed by NEAT1_2 lncRNA and different RNA-binding proteins. In general, these membraneless organelles function in the regulation of gene expression and translation and in miRNA processing, and in doing this, they
Externí odkaz:
https://doaj.org/article/a3019715d73248829d0ffb1c224bd259
Autor:
Neil Donison, Matthew Hintermayer, Maegha Subramaniam, Erin Santandrea, Kathryn Volkening, Michael J. Strong
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traumatic encephalopathy and amyotrophic lateral sclerosis with cognitive impairment. While there
Externí odkaz:
https://doaj.org/article/2299cbd01d6043df929240c2af22b231
Publikováno v:
BMC Immunology, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Autophagy is an important mechanism for promoting Mycobacterium clearance from macrophages. Pathogenic and non-pathogenic mycobacterium can activate the mTOR pathway while simultaneously inducing autophagy. M. tuberculosis and M.
Externí odkaz:
https://doaj.org/article/f7a8f0c170f3453484878eee1ad2fd23
Autor:
Nathan Stasko, Jacob F. Kocher, Abigail Annas, Ibrahim Henson, Theresa S. Seitz, Joy M. Miller, Leslee Arwood, Rachel C. Roberts, Thomas M. Womble, Emily G. Keller, Soren Emerson, Michael Bergmann, Ashley N. Y. Sheesley, Rebecca J. Strong, Brett L. Hurst, David Emerson, E. Bart Tarbet, Shelton S. Bradrick, Adam S. Cockrell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The delivery of safe, visible wavelengths of light can be an effective, pathogen-agnostic, countermeasure that would expand the current portfolio of SARS-CoV-2 intervention strategies beyond the conventional approaches of vaccine, antibody,
Externí odkaz:
https://doaj.org/article/5ec6ecc627d14875acda8d25b988d546
Autor:
Jody L. Gookin, Sandra J. Strong, José M. Bruno-Bárcena, Stephen H. Stauffer, Shelby Williams, Erica Wassack, M. Andrea Azcarate-Peril, Marko Estrada, Alexis Seguin, Joerg Balzer, Gigi Davidson
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
IntroductionDiarrhea is the second most common cause of mortality in shelter kittens. Studies examining prevention strategies in this population are lacking. Probiotics are of particular interest but studies in cats are largely limited to healthy adu
Externí odkaz:
https://doaj.org/article/d14e6e0fce82473eb7dfcfb1ab2be7aa