Zobrazeno 1 - 10 of 532 pro vyhledávání: '"A. J. Scheper"'
1
Akademický článek
Cas9-directed long-read sequencing to resolve optical genome mapping findings in leukemia diagnostics
Autor: Eddy N. de Boer, Vincent Vroom, Arjen J. Scheper, Lennart F. Johansson, Laura Bosscher, Nettie Rietema, Sabrina Z. Commandeur-Jan, Nine V. A. M. Knoers, Birgit Sikkema-Raddatz, Eva van den Berg, Cleo C. van Diemen
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Leukemias are genetically heterogeneous and diagnostics therefore includes various standard-of-care (SOC) techniques, including karyotyping, SNP-array and FISH. Optical genome mapping (OGM) may replace these as it detects different types of
Externí odkaz: https://doaj.org/article/9707ee3b98fc4b718c9354540985699f
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2
Akademický článek
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A+CD141+ cDC1 and CD14+ antigen-presenting cell recruitment
Autor: Tanja D de Gruijl, M Petrousjka van den Tol, Bas D Koster, Rik J Scheper, Barbara G Molenkamp, Alfons JM van den Eertwegh, Mari FCM van den Hout, Berbel JR Sluijter, Paul AM van Leeuwen, Marta López González, Annelies W Turksma, Saskia Vosslamber, Ekaterina J Jordanova
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background We previously reported CpG-B injection at the primary tumor excision site prior to re-excision and sentinel node biopsy to result in immune activation of the sentinel lymph node (SLN), increased melanoma-specific CD8+ T cell rates in perip
Externí odkaz: https://doaj.org/article/fe010f5cd99e4d97869e2113e46ba16a
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3
Akademický článek
The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models
Autor: Grace C. Limandjaja, Frank B. Niessen, Rik J. Scheper, Susan Gibbs
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders. This review provides a comprehensive overview of several important themes in kelo
Externí odkaz: https://doaj.org/article/b7f9eb9d099b4a328c13e1c130025109
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4
Akademický článek
Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression
Autor: Marta López González, Dinja Oosterhoff, Jelle J. Lindenberg, Ioanna Milenova, Sinead M. Lougheed, Tania Martiáñez, Henk Dekker, Dafne Carolina Alves Quixabeira, Basav Hangalapura, Jos Joore, Sander R. Piersma, Victor Cervera-Carrascon, Joao Manuel Santos, Rik J. Scheper, Henk M.W. Verheul, Connie R. Jiménez, Rieneke Van De Ven, Akseli Hemminki, Victor W. Van Beusechem, Tanja D. De Gruijl
Publikováno v: OncoImmunology, Vol 8, Iss 10 (2019)
In patients with cancer, the functionality of Dendritic Cells (DC) is hampered by high levels of tumor-derived suppressive cytokines, which interfere with DC development and maturation. Poor DC development can limit the efficacy of immune checkpoint
Externí odkaz: https://doaj.org/article/2eb62a3b396140edbdd23189bdf4b322
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