Zobrazeno 1 - 10
of 4 214
pro vyhledávání: '"A. J. Owen"'
Autor:
Grace E. Woolway, Sophie E. Legge, Amy J. Lynham, Sophie E. Smart, Leon Hubbard, Ellie R. Daniel, Antonio F. Pardiñas, Valentina Escott-Price, Michael C. O’Donovan, Michael J. Owen, Ian R. Jones, James T. R. Walters
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract The increasing availability of biobanks is changing the way individuals are identified for genomic research. This study assesses the validity of a self-reported clinical diagnosis of schizophrenia. The study included 1744 clinically-ascertai
Externí odkaz:
https://doaj.org/article/58b31096a7044b28aaa03e23b77da66d
Autor:
V. L. Patterson, L. J. Gregoire, R. F. Ivanovic, N. Gandy, J. Owen, R. S. Smith, O. G. Pollard, L. C. Astfalck, P. J. Valdes
Publikováno v:
Climate of the Past, Vol 20, Pp 2191-2218 (2024)
The configuration of the Northern Hemisphere ice sheets during the Penultimate Glacial Maximum differed to the Last Glacial Maximum. However, the reasons for this are not yet fully understood. These differences likely contributed to the varied deglac
Externí odkaz:
https://doaj.org/article/42dcf47fb07b4713ac52ec4459d736f1
Autor:
Tobias Braun, Patrick J Owen, Daniel L Belavy, Christian Kopkow, Toni Lange, Tobias Saueressig, Rilind Shala, Jochen Zebisch, Kerstin Lüdtke, Andres Jung, Katja Ehrenbrusthoff, Rebekka Döding, Bernhard Elsner, Clint Miller, Axel Schäfer, Robin Schäfer, Tim Schleimer, Tibor Szikszay
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 4 (2024)
Non-communicable diseases (NCDs) represent a high burden for the society and affected individuals. Conservative non-pharmacological interventions play a first-line role in the treatment and management of most NCDs. Systematic reviews (SRs) provide th
Externí odkaz:
https://doaj.org/article/14fa3de707d443d59ef64352d9afd0e5
Autor:
Alexander F McDonnell, Marcin Plech, Benjamin J Livesey, Lukas Gerasimavicius, Liusaidh J Owen, Hildegard Nikki Hall, David R FitzPatrick, Joseph A Marsh, Grzegorz Kudla
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 7, Pp 825-844 (2024)
Abstract Nonsense and missense mutations in the transcription factor PAX6 cause a wide range of eye development defects, including aniridia, microphthalmia and coloboma. To understand how changes of PAX6:DNA binding cause these phenotypes, we combine
Externí odkaz:
https://doaj.org/article/46f6b432ee554b1bbff01429fb10cdbb
Autor:
Jessica H. Hall, Samuel J. R. A. Chawner, IMAGINE-ID consortium, Jeanne Wolstencroft, David Skuse, Jeremy Hall, Peter Holmans, Michael J. Owen, Marianne B. M. van den Bree
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract A range of rare mutations involving micro-deletion or -duplication of genetic material (copy number variants (CNVs)) have been associated with high neurodevelopmental and psychiatric risk (ND-CNVs). Irritability is frequently observed in chi
Externí odkaz:
https://doaj.org/article/81154eda50754e09b297917153b839e0
Autor:
Josephine E. Haddon, Daniel Titherage, Julia R. Heckenast, Jennifer Carter, Michael J. Owen, Jeremy Hall, Lawrence S. Wilkinson, Matthew W. Jones
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Impaired behavioural flexibility is a core feature of neuropsychiatric disorders and is associated with underlying dysfunction of fronto-striatal circuitry. Reduced dosage of Cyfip1 is a risk factor for neuropsychiatric disorder, as evidence
Externí odkaz:
https://doaj.org/article/ff9feaf84b2d4dadb10bfac41d15a835
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Metal surfaces have long been known to reconstruct, significantly influencing their structural and catalytic properties. Many key mechanistic aspects of these subtle transformations remain poorly understood due to limitations of previous sim
Externí odkaz:
https://doaj.org/article/a573e8c612bc4b1e982f1a0a8053481e
Autor:
Cameron J. Owen, Steven B. Torrisi, Yu Xie, Simon Batzner, Kyle Bystrom, Jennifer Coulter, Albert Musaelian, Lixin Sun, Boris Kozinsky
Publikováno v:
npj Computational Materials, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract This work examines challenges associated with the accuracy of machine-learned force fields (MLFFs) for bulk solid and liquid phases of d-block elements. In exhaustive detail, we contrast the performance of force, energy, and stress predictio
Externí odkaz:
https://doaj.org/article/a68504f7e9f24d84b4a565a76a1b91db
Autor:
Evert Verhagen, Patrick J Owen, Ishtiaq Ahmed, Niamh L Mundell, Daniel L Belavy, Nash Anderson, Aamir Raoof Memon
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/1e658239e8f94d82b979d6a35babfc6b
Autor:
Arnon P. Kater, Barbara F. Eichhorst, Carolyn J. Owen, Ulrich Jaeger, Brenda Chyla, Marcus Lefebure, Rosemary Millen, Yanwen Jiang, Maria Thadani‐Mulero, Michelle Boyer, John F. Seymour
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract Immune dysregulation is a hallmark of chronic lymphocytic leukemia (CLL). Anti‐CD20 antibodies (e.g., rituximab [R]) can be combined with venetoclax (Ven) to treat CLL. However, anti‐CD20 antibodies can increase hypogammaglobulinemia ris
Externí odkaz:
https://doaj.org/article/e7a1b35722c44499b7700a85cc48aca9