Zobrazeno 1 - 10
of 112
pro vyhledávání: '"A. J. Olah"'
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Autor:
Annie M. Goettemoeller, Emmie Banks, Prateek Kumar, Viktor J. Olah, Katharine E. McCann, Kelly South, Christina C. Ramelow, Anna Eaton, Duc M. Duong, Nicholas T. Seyfried, David Weinshenker, Srikant Rangaraju, Matthew J. M. Rowan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Preventative treatment for Alzheimer’s Disease (AD) is dire, yet mechanisms underlying early regional vulnerability remain unknown. In AD, one of the earliest pathophysiological correlates to cognitive decline is hyperexcitability, which i
Externí odkaz:
https://doaj.org/article/472c8a45309c4ce99d27485c1bbd846b
Autor:
Viktor J Olah, Annie M Goettemoeller, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Publikováno v:
eLife, Vol 11 (2022)
In Alzheimer’s disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with prog
Externí odkaz:
https://doaj.org/article/48d3ee7817ef4b4e91c5efc05739463b
Autor:
Anke Vermehren-Schmaedick, Mark J. Olah, Damien Ramunno-Johnson, Keith A. Lidke, Michael S. Cohen, Tania Q. Vu
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Retrograde neurotrophin (NT) transport is a specialized form of signal transduction used to conduct information from axons to the cell bodies of central and peripheral nervous system neurons. It is activated upon NT-Trk receptor binding, NT-Trk inter
Externí odkaz:
https://doaj.org/article/c557dbe44e0f41dd8d1f5ac380c30b6a
Independent automated scoring of sleep-wake and seizures have recently been achieved; however, the combined scoring of both states has yet to be reported. Mouse models of epilepsy typically demonstrate an abnormal electroencephalographic (EEG) backgr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c02295cb152743c4b8b7123b8a5ebc
https://doi.org/10.1101/2023.04.07.536063
https://doi.org/10.1101/2023.04.07.536063
Autor:
Karl S J, Olah
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 130:244-246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a2e2458a400564e51a45ca48873bd9
https://doi.org/10.1111/1471-0528.17298
https://doi.org/10.1111/1471-0528.17298
Autor:
Annie M Goettemoeller, Viktor J Olah, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Publikováno v:
eLife. 11
In Alzheimer’s disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0130f9f7fa3436087c675b7d6c1738a
https://doi.org/10.7554/elife.75316
https://doi.org/10.7554/elife.75316
Autor:
Annie M Goettemoeller, Viktor J Olah, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc80aa748de97f2ad4bab58686ecfae
https://doi.org/10.7554/elife.75316.sa2
https://doi.org/10.7554/elife.75316.sa2
Autor:
K. Lewis, C. Robert, R. Ramella Munhoz, G. Liszkay, L. de la Cruz Merino, J. Olah, P. Queirolo, J. Mackiewicz, H. Li, Q. Zhu, C. Hertig, N. Paranthaman, E.F. McKenna, R. Gutzmer, G. McArthur, P.A. Ascierto
Publikováno v:
Annals of Oncology. 33:S917-S918
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9969277996ba8783a611f94d0ace27e0
https://doi.org/10.1016/j.annonc.2022.07.939
https://doi.org/10.1016/j.annonc.2022.07.939
Autor:
Viktor J, Olah, Annie M, Goettemoeller, Sruti, Rayaprolu, Eric B, Dammer, Nicholas T, Seyfried, Srikant, Rangaraju, Jordane, Dimidschstein, Matthew J M, Rowan
Publikováno v:
eLife. 11
In Alzheimer's disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6dda09026420668daf99165f016ebf58
https://pubmed.ncbi.nlm.nih.gov/35727131
https://pubmed.ncbi.nlm.nih.gov/35727131
Autor:
Peter K. Relich, Genevieve K Phillips, William S. Hlavacek, Mark J. Olah, Samantha L. Schwartz, Cédric Cleyrat, Keith A. Lidke, Diane S. Lidke, Bridget S. Wilson
Publikováno v:
Molecular Biology of the Cell
Single-molecule imaging was used to quantify the transient nature of FcεRI-Syk interactions in a rodent mast cell line. A functional mutation that increases Syk off-rate leads to altered Syk phosphorylation patterns and impaired signaling, highlight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381e77b254613f536325160600735bef
https://doi.org/10.1091/mbc.e17-06-0350
https://doi.org/10.1091/mbc.e17-06-0350