Zobrazeno 1 - 10
of 1 001
pro vyhledávání: '"A. J. North"'
Autor:
Sherif Abouelhadid, Elizabeth R. Atkins, Emily J. Kay, Ian J. Passmore, Simon J. North, Burhan Lehri, Paul Hitchen, Eirik Bakke, Mohammed Rahman, Janine T. Bossé, Yanwen Li, Vanessa S. Terra, Paul R. Langford, Anne Dell, Brendan W. Wren, Jon Cuccui
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine assembly and production have sev
Externí odkaz:
https://doaj.org/article/7c268aec51534a47a4626a4fff3d99d6
Autor:
Renju Pun, Ann M. Cavanaugh, Emily Aldrich, Olivia Tran, Justin C. Rudd, Laura A. Hansen, Brian J. North
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109033- (2024)
Summary: Downregulation of intercellular communication through suppression of gap junctional conductance is necessary during wound healing. Connexin 43 (Cx43), a prominent gap junction protein in skin, is downregulated following wounding to restrict
Externí odkaz:
https://doaj.org/article/624770dd6e62454ea5ffd5b68a5ab364
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 103993- (2024)
Externí odkaz:
https://doaj.org/article/b5ef2aa68662423995933ad3ed2f9cb8
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
Intercellular communication mediated by gap junction channels and hemichannels composed of Connexin 43 (Cx43) is vital for the propagation of electrical impulses through cardiomyocytes. The carboxyl terminal tail of Cx43 undergoes various post-transl
Externí odkaz:
https://doaj.org/article/8dd9b462f8744d4f849c4ad1cda6bcfd
Autor:
Jing Liu, Collin Tokheim, Jonathan D. Lee, Wenjian Gan, Brian J. North, X. Shirley Liu, Pier Paolo Pandolfi, Wenyi Wei
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The impact of genetic fusions on degrons, which are motifs for ubiquitin-mediated protein degradation, has not been fully explored. Here, the authors analyse fusion genes affecting degrons in pan-cancer genomics data, validate their functional impact
Externí odkaz:
https://doaj.org/article/94598e27d4dd4b42ab93f5a55245e282
Publikováno v:
eLife, Vol 11 (2022)
Piezo1 is the stretch activated Ca2+ channel in red blood cells that mediates homeostatic volume control. Here, we study the organization of Piezo1 in red blood cells using a combination of super-resolution microscopy techniques and electron microsco
Externí odkaz:
https://doaj.org/article/9c53011f2546426dabb03677f0c1a68f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/8f3be29ee95a457e9654baa2f75bf25c
Autor:
Celia R. Bloom, Brian J. North
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract BubR1 is an essential component of the spindle assembly checkpoint (SAC) during mitosis where it functions to prevent anaphase onset to ensure proper chromosome alignment and kinetochore-microtubule attachment. Loss or mutation of BubR1 resu
Externí odkaz:
https://doaj.org/article/756d823607f2409cba8587ec62b97c3e
Publikováno v:
Frontiers in Earth Science, Vol 10 (2022)
Gas bubble in aquatic sediments has a significant effect on its geophysical and geomechanical properties. Recent studies have shown that methane gas and hydrate can coexist in gas hydrate–bearing sediments. Accurate calibration and understanding of
Externí odkaz:
https://doaj.org/article/c38078735c3b4048b71bf5be6bb4006c
Publikováno v:
Advances in Statistical Climatology, Meteorology and Oceanography, Vol 6, Pp 79-90 (2020)
Thunderstorms and associated hazards like lightning can pose a serious threat to people outside and infrastructure. Thus, very short-term prediction capabilities (called nowcasting) have been developed to capture this threat and aid in decision-makin
Externí odkaz:
https://doaj.org/article/d6d6627a9c514e0abf76762146a04829