Zobrazeno 1 - 10
of 376
pro vyhledávání: '"A. J. Marr"'
Autor:
Friedrich Stölzel, Sarah E. Fordham, Devi Nandana, Wei-Yu Lin, Helen Blair, Claire Elstob, Hayden L. Bell, Brigitte Mohr, Leo Ruhnke, Desiree Kunadt, Claudia Dill, Daniel Allsop, Rachel Piddock, Emmanouela-Niki Soura, Catherine Park, Mohd Fadly, Thahira Rahman, Abrar Alharbi, Manja Wobus, Heidi Altmann, Christoph Röllig, Lisa Wagenführ, Gail L. Jones, Tobias Menne, Graham H. Jackson, Helen J. Marr, Jude Fitzgibbon, Kenan Onel, Manja Meggendorfer, Amber Robinson, Zuzanna Bziuk, Emily Bowes, Olaf Heidenreich, Torsten Haferlach, Sara Villar, Beñat Ariceta, Rosa Ayala Diaz, Steven J. Altschuler, Lani F. Wu, Felipe Prosper, Pau Montesinos, Joaquin Martinez-Lopez, Martin Bornhäuser, James M. Allan
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Precision medicine can significantly improve outcomes for patients with cancer, but implementation requires comprehensive characterization of tumor cells to identify therapeutically exploitable vulnerabilities. Here, we describe somatic biallelic TET
Externí odkaz:
https://doaj.org/article/099cf4b757194708b07592874d0436b2
Autor:
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Genome wide association studies in cancer are used to understand the heritable genetic contribution to disease risk. Here, the authors perform a genome wide association study in European patients with acute myeloid leukemia and identify loci associat
Externí odkaz:
https://doaj.org/article/b98174c0ab9448b282785b148dd6b082
Autor:
Stewart T. G. Burgess, Edward J. Marr, Kathryn Bartley, Francesca G. Nunn, Rachel E. Down, Robert J. Weaver, Jessica C. Prickett, Jackie Dunn, Stephane Rombauts, Thomas Van Leeuwen, Yves Van de Peer, Alasdair J. Nisbet
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract Background Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide. Cont
Externí odkaz:
https://doaj.org/article/5a54e6b9e0f445f2bed6b7c80ffdd752
Autor:
Edward J Marr, Rachel M Milne, Burcu Anar, Gareth Girling, Frank Schwach, Jason P Mooney, Wiebke Nahrendorf, Philip J Spence, Deirdre Cunningham, David A Baker, Jean Langhorne, Julian C Rayner, Oliver Billker, Ellen S Bushell, Joanne Thompson
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
The rodent parasite Plasmodium chabaudi is an important in vivo model of malaria. The ability to produce chronic infections makes it particularly useful for investigating the development of anti-Plasmodium immunity, as well as features associated wit
Externí odkaz:
https://doaj.org/article/7106878d927f425095d4eb60765d87dd
Autor:
Edward J Marr, Rachel M Milne, Burcu Anar, Gareth Girling, Frank Schwach, Jason P Mooney, Wiebke Nahrendorf, Philip J Spence, Deirdre Cunningham, David A Baker, Jean Langhorne, Julian C Rayner, Oliver Billker, Ellen S Bushell, Joanne Thompson
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
The rodent parasite Plasmodium chabaudi is an important in vivo model of malaria. The ability to produce chronic infections makes it particularly useful for investigating the development of anti-Plasmodium immunity, as well as features associated wit
Externí odkaz:
https://doaj.org/article/73142696bd304da193f9a5f512b43ee3
Publikováno v:
Veterinary Research, Vol 49, Iss 1, Pp 1-11 (2018)
Abstract The presence of components of the RNA interference (RNAi) pathway in Psoroptes ovis, an ectoparasitic mite responsible for psoroptic mange, was investigated through interrogation of the P. ovis genome. Homologues of transcripts representing
Externí odkaz:
https://doaj.org/article/0ede8864619c4f50934c810a8eca9a77
Autor:
Sarah E. Fordham, Helen J. Blair, Claire J. Elstob, Ruth Plummer, Yvette Drew, Nicola J. Curtin, Olaf Heidenreich, Deepali Pal, David Jamieson, Catherine Park, John Pollard, Scott Fields, Paul Milne, Graham H. Jackson, Helen J. Marr, Tobias Menne, Gail L. Jones, James M. Allan
Publikováno v:
Blood Advances, Vol 2, Iss 10, Pp 1157-1169 (2018)
Abstract: The ataxia telangiectasia and Rad3-related (ATR) protein kinase promotes cancer cell survival by signaling stalled replication forks generated by replication stress, a common feature of many cancers including acute myeloid leukemia (AML). H
Externí odkaz:
https://doaj.org/article/61768a4bf39943d4a87bca41dd7f4f9c
Autor:
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovanni Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1723b41ffb3e40a6be29fdc671afedd7
Autor:
Deepani D. Fernando, Edward J. Marr, Martha Zakrzewski, Simone L. Reynolds, Stewart T. G. Burgess, Katja Fischer
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-10 (2017)
Abstract Background Scabies is one of the most common and widespread parasitic skin infections globally, affecting a large range of mammals including humans, yet the molecular biology of Sarcoptes scabiei is astonishingly understudied. Research has b
Externí odkaz:
https://doaj.org/article/7a576c0f2d174bb0b32bca0838988ffe
Autor:
Jorge Cañizares-Esguerra, Marcella Trambaioli, Ascensión Rivas Hernández, David T. Gies, John McCulloch, Michael Eaude, Alvin F. Sherman, Matthew J. Marr, Barry Taylor, Fernando Villegas Torres, Jason Wilson, Sarah E. L. Bowskill, Anthony Pasero, Robin Greeley, Eduardo Ledesma
Publikováno v:
Bulletin of Spanish Studies. 99:1065-1089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f79270c71d431ec66db070f893ceb57
https://doi.org/10.1080/14753820.2022.2142385
https://doi.org/10.1080/14753820.2022.2142385