Zobrazeno 1 - 10
of 92
pro vyhledávání: '"A. J. Markworth"'
Autor:
David C. Pryde, Brian E. Marron, Peter J. Cox, C. J. Markworth, Joseph S. Warmus, Christopher William West, David Printzenhoff, S. McMurray, Stupple Paul Anthony, Zhixin Lin, Nigel Alan Swain, Mark L. Chapman, C. E. Payne, Ryoichi Suzuki, Gareth Waldron
Publikováno v:
MedChemComm. 8:1255-1267
In this article, we describe the discovery of an aryl ether series of potent and selective Nav1.3 inhibitors. Based on structural analogy to a similar series of compounds we have previously shown bind to the domain IV voltage sensor region of Nav cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686aba00c31c3db790fd73e2323a9e86
https://doi.org/10.1039/c7md00131b
https://doi.org/10.1039/c7md00131b
Autor:
D C, Pryde, N A, Swain, P A, Stupple, C W, West, B, Marron, C J, Markworth, D, Printzenhoff, Z, Lin, P J, Cox, R, Suzuki, S, McMurray, G J, Waldron, C E, Payne, J S, Warmus, M L, Chapman
An aryl ether series of potent and selective Nav1.3 inhibitors is described, starting from a series of diphenymethyl amides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e957ded6a387b568796997233ea51d43
https://europepmc.org/articles/PMC6072313/
https://europepmc.org/articles/PMC6072313/
Autor:
Dean E. Wilcox, Christopher J. Markworth, Fredrick J. Kull, Benjamin D. Malkin, Karen R. Thickman
Publikováno v:
Journal of Enzyme Inhibition. 16:135-145
The activity of potato polyphenol oxidase (tyrosinase) toward DL-3,4-dihydroxyphenylalanine (K(M) 5.39 mM) was studied using a variety of carboxylate buffers at a common pH and ionic strength. Enzyme activity, greatest in citrate and least in oxalate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adbb3765a2e3d43219ee5ab45a204bf
https://doi.org/10.1080/14756360109162363
https://doi.org/10.1080/14756360109162363
Publikováno v:
Journal of The Electrochemical Society. 146:3672-3678
Support of this work by the Atomic Energy Control Board under AECB project no. 2.349.1 is gratefully acknowledged.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4d1e33e1f483cfd20e1fb255f4ec804
https://doi.org/10.1149/1.1392532
https://doi.org/10.1149/1.1392532
Publikováno v:
Materials Science and Engineering: A. 270:254-259
The corrosion resistance of a metal surface in contact with an aqueous medium can, in principle, be improved by imposing conditions that cause the otherwise chemically active surface to be passivated. In this work, several different control strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c51baed3f1374fdbb2b556b675f85c7
https://doi.org/10.1016/s0921-5093(99)00195-1
https://doi.org/10.1016/s0921-5093(99)00195-1
Publikováno v:
Journal of Materials Science. 34:4141-4147
Simulation of deposit growth on a two-dimensional substrate was studied based on a new model that tracks individual cubic particles as they form a deposit structure. The present model is an extension of the classical ballistic deposition model. Effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1218e7d64603ecbf7de13dc37629ae
https://doi.org/10.1023/a:1004613727145
https://doi.org/10.1023/a:1004613727145
Publikováno v:
Journal of Materials Science. 34:5497-5503
We describe two methods for modeling the thermal conductivity and temperature profile in a graded composite film. The film consists of a random binary composite, whose concentration varies in the direction perpendicular to the film surface, and a fix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e6d8ddaa67053e9cd678d88d378598
https://doi.org/10.1023/a:1004760427981
https://doi.org/10.1023/a:1004760427981
Publikováno v:
Scripta Materialia. 39:481-486
The Portevin-Le Chatelier (PLC) effect, otherwise known as serrated yielding, repeated yielding, or jerky flow, has been a subject of investigation for many years. Modeling studies, and experiments have shown that the oscillatory PLC stress-strain dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53203af1ad51a49adeeca9a0fcfe079
https://doi.org/10.1016/s1359-6462(98)00225-5
https://doi.org/10.1016/s1359-6462(98)00225-5
Publikováno v:
Materials Letters. 36:102-108
A new approach to obtaining information about a chaotic system is considered. The essence of the method lies in analysis of the statistics of repetitive experiments carried out under slightly varying initial conditions. This approach does not require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::643adb7e1b4a0c79cf654bb43fd43d91
https://doi.org/10.1016/s0167-577x(98)00015-9
https://doi.org/10.1016/s0167-577x(98)00015-9
Autor:
Alan J. Markworth, Anthony M. Bloch
Publikováno v:
Modelling and Simulation in Materials Science and Engineering. 4:641-653
A method of linear feedback is shown to be applicable to the control or suppression of spontaneously occurring relaxation oscillations in a two-dimensional model for the passivation of a metal surface exposed to an aqueous medium. For the operating c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8395164f54ac4c6752c492bd958e1670
https://doi.org/10.1088/0965-0393/4/6/007
https://doi.org/10.1088/0965-0393/4/6/007