Zobrazeno 1 - 10
of 134
pro vyhledávání: '"A. J. Kozielski"'
Autor:
Andrew W. Chung, Anthony J. Kozielski, Wei Qian, Jianying Zhou, Ann C. Anselme, Alfred A. Chan, Ping-Ying Pan, Delphine J. Lee, Jenny C. Chang
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Triple-negative breast cancer (TNBC) patients with mesenchymal stem-like (MSL) subtype have responded poorly to chemotherapy whereas patients with basal-like 1 (BL1) subtype achieved the best clinical response. In order to gain insight into
Externí odkaz:
https://doaj.org/article/f35ee9f823934baea9f5adb11e89df96
Autor:
Roberto R. Rosato, Daniel Dávila-González, Dong Soon Choi, Wei Qian, Wen Chen, Anthony J. Kozielski, Helen Wong, Bhuvanesh Dave, Jenny C. Chang
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-16 (2018)
Abstract Background Breast cancer has been considered not highly immunogenic, and few patients benefit from current immunotherapies. However, new strategies are aimed at changing this paradigm. In the present study, we examined the in vivo activity o
Externí odkaz:
https://doaj.org/article/82c3a593740f453a94431feea13df07e
Autor:
Qi Cao, Kaifu Chen, Akash Patnaik, Jenny C. Chang, Wei Qian, Anthony J. Kozielski, Xiongbing Zu, Jung-Sun Kim, Lili Zhang, Lin Yan, Dongyu Zhao, Longxiang Wu, Chao Li, Sen Zhu, Rui Wang, Yongyong Yang, Yang Yi, Qingshu Meng, Weihua Jiang, Guangyu Wang, Qipeng Liu, Kilia Y. Liu, Qiaqia Li
Enhancer of zester homolog 2 (EZH2), a histone lysine methyltransferase and the catalytic component of polycomb repressive complex 2, has been extensively investigated as a chromatin regulator and a transcriptional suppressor by methylating H3 at lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1943c9e604d6453405b29333bb9a10
https://doi.org/10.1158/1535-7163.c.6542673.v1
https://doi.org/10.1158/1535-7163.c.6542673.v1
Autor:
Qi Cao, Kaifu Chen, Akash Patnaik, Jenny C. Chang, Wei Qian, Anthony J. Kozielski, Xiongbing Zu, Jung-Sun Kim, Lili Zhang, Lin Yan, Dongyu Zhao, Longxiang Wu, Chao Li, Sen Zhu, Rui Wang, Yongyong Yang, Yang Yi, Qingshu Meng, Weihua Jiang, Guangyu Wang, Qipeng Liu, Kilia Y. Liu, Qiaqia Li
Supplementary Data File
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a93250320a9e54373fe6adefc5c82e
https://doi.org/10.1158/1535-7163.22520532
https://doi.org/10.1158/1535-7163.22520532
Autor:
Sergio Granados-Principal, Jenny C. Chang, Pedro Sánchez-Rovira, Jose A. Lorente, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Hanna Kim, Cesar L. Ramirez-Tortosa, Maria A. García, Roberto R. Rosato, María Quintana-Romero, David Landeira, Carmen Rosa-Garrido, Rafael J. Luque, María D. Martín-Salvago, Olivier Elemento, Anthony J. Kozielski, Wen Chen, Wei Qian, Alberto Ramírez, Akanksha Verma, Gema Jiménez, Marina Cruz-Lozano, Maria P. Molina, Francisca E. Cara, Juan A. Marchal, Esperanza Muñoz-Muela, Adrián González-González
Supplementary Figure 1. Patient survival with high ATF4 expression in ER+ patients. ROC curve. Differential ATF4 expression induced by TGFβ1 and ERS. SBE motifs in ATF4 promoter and ChiP-Seq analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539322f9339088f63775a28c8ad9d07c
https://doi.org/10.1158/1078-0432.22470821
https://doi.org/10.1158/1078-0432.22470821
Autor:
Sergio Granados-Principal, Jenny C. Chang, Pedro Sánchez-Rovira, Jose A. Lorente, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Hanna Kim, Cesar L. Ramirez-Tortosa, Maria A. García, Roberto R. Rosato, María Quintana-Romero, David Landeira, Carmen Rosa-Garrido, Rafael J. Luque, María D. Martín-Salvago, Olivier Elemento, Anthony J. Kozielski, Wen Chen, Wei Qian, Alberto Ramírez, Akanksha Verma, Gema Jiménez, Marina Cruz-Lozano, Maria P. Molina, Francisca E. Cara, Juan A. Marchal, Esperanza Muñoz-Muela, Adrián González-González
Supplementary Table S3. Relapse-free survival of gene signature and single genes according to intrinsic subtype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399c221e85c0b17b4ed72338819d2bdb
https://doi.org/10.1158/1078-0432.22470794
https://doi.org/10.1158/1078-0432.22470794
Autor:
Jenny C. Chang, Bhuvanesh Dave, Helen Wong, Anthony J. Kozielski, Wen Chen, Wei Qian, Wen-Feng Li, John G. Kuhn, Sergio M. Granados-Principal, Roberto R. Rosato, Dong Soon Choi, Daniel Dávila-González
Purpose: Chemoresistance in triple-negative breast cancer (TNBC) is associated with the activation of a survival mechanism orchestrated by the endoplasmic reticulum (EnR) stress response and by inducible nitric oxide synthase (iNOS). Our aim was to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0398df70623b0908725de61034e3db92
https://doi.org/10.1158/1078-0432.c.6525564
https://doi.org/10.1158/1078-0432.c.6525564
Autor:
Jenny C. Chang, Bhuvanesh Dave, Helen Wong, Anthony J. Kozielski, Wen Chen, Wei Qian, Wen-Feng Li, John G. Kuhn, Sergio M. Granados-Principal, Roberto R. Rosato, Dong Soon Choi, Daniel Dávila-González
Supplemental Figure 1. Docetaxel induce the expression of iNOS following a bell shape distribution, no consistent effect is observed on eNOS; Supplemental Figure 2. L-NMMA decreased iNOS and enhances docetaxel toxicity on MDA-MB 468; Supplemental Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7f05b927f0bb865943bbfaee417b35
https://doi.org/10.1158/1078-0432.22463898.v1
https://doi.org/10.1158/1078-0432.22463898.v1
Autor:
Sergio Granados-Principal, Jenny C. Chang, Pedro Sánchez-Rovira, Jose A. Lorente, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Hanna Kim, Cesar L. Ramirez-Tortosa, Maria A. García, Roberto R. Rosato, María Quintana-Romero, David Landeira, Carmen Rosa-Garrido, Rafael J. Luque, María D. Martín-Salvago, Olivier Elemento, Anthony J. Kozielski, Wen Chen, Wei Qian, Alberto Ramírez, Akanksha Verma, Gema Jiménez, Marina Cruz-Lozano, Maria P. Molina, Francisca E. Cara, Juan A. Marchal, Esperanza Muñoz-Muela, Adrián González-González
Purpose: On the basis of the identified stress-independent cellular functions of activating transcription factor 4 (ATF4), we reported enhanced ATF4 levels in MCF10A cells treated with TGFβ1. ATF4 is overexpressed in patients with triple-negative br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2974b96a0cfd31f0352796594f8e6f51
https://doi.org/10.1158/1078-0432.c.6527690.v1
https://doi.org/10.1158/1078-0432.c.6527690.v1
Autor:
Andrew W, Chung, Anthony J, Kozielski, Wei, Qian, Jianying, Zhou, Ann C, Anselme, Alfred A, Chan, Ping-Ying, Pan, Delphine J, Lee, Jenny C, Chang
Publikováno v:
NPJ breast cancer. 8(1)
Triple-negative breast cancer (TNBC) patients with mesenchymal stem-like (MSL) subtype have responded poorly to chemotherapy whereas patients with basal-like 1 (BL1) subtype achieved the best clinical response. In order to gain insight into pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbdaf59700a1043e17d7fc0846c8baa9
https://pubmed.ncbi.nlm.nih.gov/35260569
https://pubmed.ncbi.nlm.nih.gov/35260569