Zobrazeno 1 - 10
of 53
pro vyhledávání: '"A. J. Konecny"'
Autor:
Kyle G. Williams, Ramya Kongala, Donna M. Shows, Andrew J. Konecny, Duncan C. Hindmarch, Astrid S. Clarke, James D. Lord
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 119-130 (2024)
Background & Aims: Inflammatory bowel disease (IBD) causes a marked increase in the number of T cells in the intestinal mucosa. Debate exists about whether these excess cells arise from local clonal proliferation or recruitment from the periphery. Me
Externí odkaz:
https://doaj.org/article/ee9454018c844a7b80fe3559c671e348
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0285918 (2023)
ObjectivesMucosal-Associated Invariant T (MAIT) cells are T cells with a semi-invariant T cell receptor (TCR), recognizing riboflavin precursors presented by a non-polymorphic MR1 molecule. As these precursors are produced by the gut microbiome, we c
Externí odkaz:
https://doaj.org/article/a8d7982345744f61a52d4f080210c251
Autor:
Amiko M. Uchida, Elisa K. Boden, Eddie A. James, Donna M. Shows, Andrew J. Konecny, James D. Lord
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 507-526 (2020)
Background & Aims: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of
Externí odkaz:
https://doaj.org/article/98759850dda64024b22ff773edf37060
Autor:
M. Novak, B. Svobodova, J. Konecny, A. Kuratkova, L. Nevosadova, L. Prchal, J. Korabecny, V.M. Lauschke, O. Soukup, R. Kučera
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 224
Tacrine was the first drug used in the therapy of Alzheimer's disease (AD) and is one of the leading structures frequently pursued in the drug discovery of novel candidates for tackling AD. However, because tacrine has been withdrawn from the market
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eda7b1759002596a0b9deead322293a
https://pubmed.ncbi.nlm.nih.gov/36442458
https://pubmed.ncbi.nlm.nih.gov/36442458
Publikováno v:
ImmunoHorizons. 6(3)
Successful treatment of inflammatory bowel disease (IBD) with the anti-integrin α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8fee797b3f558cfc73d8ba62b9d4627
https://pubmed.ncbi.nlm.nih.gov/35273097
https://pubmed.ncbi.nlm.nih.gov/35273097
Autor:
Raphael Gottardo, Florian Mair, Martin Prlic, Nicholas Franko, Sarah C. Vick, Joshua T. Schiffer, Evan Greene, Helen Y. Chu, Caitlin R Wolf, Jennifer Logue, Jim Boonyaratanakornkit, Jennifer M. Lund, Marie Frutoso, Andrew J. Konecny
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SARS-CoV-2 infection has caused a lasting global pandemic costing millions of lives and untold additional costs. Understanding the immune response to SARS-CoV-2 has been one of the main challenges in the past year in order to decipher mechanisms of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9735c85dcfa272362097b8c1c5ef0d5
https://pubmed.ncbi.nlm.nih.gov/33791720
https://pubmed.ncbi.nlm.nih.gov/33791720
Publikováno v:
Radioengineering, Vol 15, Iss 4, Pp 52-57 (2006)
The UWB (ultra wide band) radar output signals can be substantially affected due to electromagnetic wave propagation through obstacles (such as walls) and multipath effects, too. Multipath effects are analyzed and simulated numerically for various ca
Externí odkaz:
https://doaj.org/article/5400c2ada42d433d81a13196acbc3bb6
Publikováno v:
Bulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics, Vol 12(61), Iss 1, Pp 75-84 (2019)
The aim of the study was to determine the growth of explosive strength in both lower extremities in ice hockey players in the course of several years training cycles (later as RTC). Measurement was carried out at the beginning of the competitive seas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5dff42e974fe2d4439f59c6ef1d71f
https://doi.org/10.31926/but.shk.2019.12.61.15
https://doi.org/10.31926/but.shk.2019.12.61.15
Autor:
Martin Prlic, Brittany Barber, Andrew J. Konecny, Florian Mair, Jami R. Erickson, Evan Greene, Douglas R. Dixon, Marie Frutoso, Raphael Gottardo, Valentin Voillet
Immunotherapies to treat cancer have achieved remarkable successes, but major challenges persist. An inherent weakness of current treatment approaches is that therapeutically targeted pathways are not only found in tumors, but also in tissue microenv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2964b42029b93b9063bf2b82f00f8275
https://doi.org/10.21203/rs.3.rs-356214/v1
https://doi.org/10.21203/rs.3.rs-356214/v1
Autor:
Joshua T. Schiffer, Martin Prlic, A. J. Konecny, Florian Mair, Evan Greene, Raphael Gottardo, Caitlin R Wolf, Jim Boonyaratanakornkit, Jennifer M. Lund, Marie Frutoso, Helen Y. Chu, Sarah C. Vick, Jennifer Logue
Publikováno v:
Science Advances
Description
Unique circulating regulatory T cell phenotypes distinguish hospitalized patients with SARS-CoV-2.
Despite recent studies of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), little is known about how the
Unique circulating regulatory T cell phenotypes distinguish hospitalized patients with SARS-CoV-2.
Despite recent studies of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), little is known about how the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a79734f4b912c8b9e303283335ce10
https://doi.org/10.1101/2021.03.25.21254376
https://doi.org/10.1101/2021.03.25.21254376