Zobrazeno 1 - 10
of 91
pro vyhledávání: '"A. J. Hapel"'
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2394 (2023)
Neuroinflammation may be a pathogenic mediator and biomarker of neurodegeneration at the boundary between mild cognitive impairment (MCI) and early-stage Alzheimer’s disease (AD). Whether neuroinflammatory processes are endogenous to the central ne
Externí odkaz:
https://doaj.org/article/4b2c490ac7e7497e82df6b4411c4f6fe
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95208 (2014)
Unraveling the mechanisms of hematopoiesis regulated by multiple cytokines remains a challenge in hematology. IL-3 is an allergic cytokine with the multilineage potential, while CSF-1 is produced in the steady state with restricted lineage coverage.
Externí odkaz:
https://doaj.org/article/c7d6ec5110504ff19db65bb90cd21132
Publikováno v:
Journal of Clinical and Experimental Hematopathology. 53:115-120
4) Myb-transformed haematopoietic cell (MTHC) lines have been developed and clones selected based on their ability to respond to tumor necrosis factor (TNF)-a. MTHC-A cells underwent apoptosis in response to TNF-a (MTHC-A). The apoptotic effect of TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75f0121c88b1e51d35c15039ba04f6e
https://doi.org/10.3960/jslrt.53.115
https://doi.org/10.3960/jslrt.53.115
Autor:
N. H. R. Hamilton, J. L. Banyer, A. J. Hapel, S. Mahalingam, A. J. Ramsay, I. A. Ramshaw, S. A. Thomson
Publikováno v:
Scandinavian Journal of Immunology. 55:171-177
The authors have analysed gliadin specific, CD4+ T cells isolated from small intestinal biopsies of 23 adult coeliac disease patients (20 on a gluten-free diet and three untreated) and nine control patients. The biopsies were stimulated ex vivo with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b25720a3da9088fc858f38f2a002065
https://doi.org/10.1046/j.1365-3083.1997.d01-93.x
https://doi.org/10.1046/j.1365-3083.1997.d01-93.x
Autor:
Nicholas H R Hamilton, Alistair J. Ramsay, Surendran Mahalingam, Ian A. Ramshaw, Scott Thomson, Joanne Banyer, Andrew J. Hapel
Publikováno v:
Scandinavian Journal of Immunology. 55:53-60
Murine interferon-inducible T cell alpha chemokine (I-TAC) is a potent non-ELR Cys-X-Cys (CXC) chemokine that predominantly attracts activated T lymphocytes and binds to the receptor CXCR3. Using semiquantitative reverse transcription–polymerase ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd1adb2c1c4e513adbde1693639a1c15
https://doi.org/10.1046/j.0300-9475.2001.01019.x
https://doi.org/10.1046/j.0300-9475.2001.01019.x
Autor:
David A. Mann, Ian G. Young, Michelle J. Townsend, C. F. Morris, Andrew J. Hapel, Ming Chiu Fung, J. Dennis Wilson, Charmaine J. Simeonovic
Publikováno v:
Transplantation. 67:963-971
Background. Previous in vivo depletion studies of CD4 and CD8 T cells indicated that different rejection mechanisms operate for proislet allografts and xenografts. The cellular and molecular mechanisms of acute proislet allograft and xenograft reject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855952258e8dd46393c5703a4363fa44
https://doi.org/10.1097/00007890-199904150-00006
https://doi.org/10.1097/00007890-199904150-00006
Autor:
Maheshi Prabodani Obeysekera, Adam Taylor, Andrew Zakhary, Suresh Mahalingam, Kuo-Ching Sheng, Lara J. Herrero, Michelle Nelson, Stefan Wolf, Michelle E. Gahan, Belinda L. Herring, Shobha Broor, Jayaram Bettadapura, Andrew J. Hapel, Paul A. Keller, Lalit Dar, Weiqiang Chen
Publikováno v:
Pharmacologytherapeutics. 137(2)
Dengue virus (DV) is the most widespread arbovirus, being endemic in over 100 countries, and is estimated to cause 50 million infections annually. Viral factors, such as the genetic composition of the virus strain can play a role in determining the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c4aad872d2616207d7b66e7cb0c34a
https://pubmed.ncbi.nlm.nih.gov/23103333
https://pubmed.ncbi.nlm.nih.gov/23103333
Autor:
Andrew J. Hapel, Stephen J. Galli, George F.J. Newlands, Donna R. Cohen, Raj Sangha, Lesley Inglis, David M. Haig, John F. Huntley, A. Mackellar, Hugh R. P. Miller
Publikováno v:
Blood. 83:72-83
The effects of rat stem-cell factor (SCF) and interleukin-3 (IL-3), alone or in combination, on the in vitro growth and serine proteinase expression of rat serosal/connective-tissue mast cells (CTMC) or bone marrow-derived mast cells (BMMC) were exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2309f373bf3f9cd76a7727da00d13e
https://doi.org/10.1182/blood.v83.1.72.72
https://doi.org/10.1182/blood.v83.1.72.72
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 54:305-307
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3e9ba3e36084f83aa56290601e597f2
https://doi.org/10.1080/15216540215680
https://doi.org/10.1080/15216540215680
Publikováno v:
Blood. 82:2813-2822
Murine hematopoietic cells can be transformed in vitro by recombinant retroviruses that express the myb oncogene, and hematopoietic growth factor (HGF)-dependent myeloid cell lines can be derived from these transformed primary cells. In this study, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b75c0d464b461d3a411d5b8d7482f528
https://doi.org/10.1182/blood.v82.9.2813.2813
https://doi.org/10.1182/blood.v82.9.2813.2813