Zobrazeno 1 - 10
of 169
pro vyhledávání: '"A. J. H. Simpson"'
Autor:
Khemngeun Pongmala, Alain Pierret, Priscia Oliva, Anne Pando, Viengmon Davong, Sayaphet Rattanavong, Norbert Silvera, Manophab Luangraj, Laurie Boithias, Khampaseuth Xayyathip, Ludovic Menjot, Melina Macouin, Emma Rochelle-Newall, Henri Robain, Amphone Vongvixay, Andrew J. H. Simpson, David A. B. Dance, Olivier Ribolzi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The environmental distribution of Burkholderia pseudomallei, the causative agent of melioidosis, remains poorly understood. B. pseudomallei is known to have the ability to occupy a variety of environmental niches, particularly in soil. This
Externí odkaz:
https://doaj.org/article/e9c8c27fc0564c2b8e73c78238195454
Autor:
Wanitda Watthanaworawit, Tamalee Roberts, Jill Hopkins, Ian Gassiep, Robert Norton, Matthew T. Robinson, Joy Silisouk, Poda Sar, Sena Sao, Premjit Amornchai, Direk Limmathurotsakul, Vanaporn Wuthiekanun, Francois Nosten, Andrew J. H. Simpson, Paul Turner, Clare L. Ling
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Burkholderia pseudomallei is the bacterial causative agent of melioidosis, a difficult disease to diagnose clinically with high mortality if not appropriately treated. Definitive diagnosis requires isolation and identification of
Externí odkaz:
https://doaj.org/article/597d5a5875324278ad1a2b8fd90800a4
Autor:
Betsy Wonderly, Sophie Jones, Michelle L Gatton, John Barber, Marian Killip, Chris Hudson, Lisa Carter, Tim Brooks, Andrew J H Simpson, Amanda Semper, Willy Urassa, Arlene Chua, Mark Perkins, Catharina Boehme
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212113 (2019)
BackgroundWithout an effective vaccine, as was the case early in the 2014-2016 Ebola Outbreak in West Africa, disease control depends entirely on interrupting transmission through early disease detection and prompt patient isolation. Lateral Flow Imm
Externí odkaz:
https://doaj.org/article/80fd681ff9f44613a4cf9b2abd6069c8
Autor:
Kevin Wing, Shefali Oza, Catherine Houlihan, Judith R Glynn, Sharon Irvine, Clare E Warrell, Andrew J H Simpson, Sabah Boufkhed, Alieu Sesay, Lahai Vandi, Sahr Charles Sebba, Pranav Shetty, Rachael Cummings, Francesco Checchi, Catherine R McGowan
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209655 (2018)
BackgroundWhile a number of predictors for Ebola mortality have been identified, less is known about post-viral symptoms. The identification of acute-illness predictors for post-viral symptoms could allow the selection of patients for more active fol
Externí odkaz:
https://doaj.org/article/db394121e0314310b8b641edef613434
Autor:
Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy J G Brooks, Andrew J H Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, Mauricio Ferri, Jennifer Grove, Mark Kowalski, Kasia Stepniewska, Trudie Lang, John Whitehead, Piero Olliaro, Mohammed Samai, Peter W Horby, RAPIDE-TKM trial team
Publikováno v:
PLoS Medicine, Vol 13, Iss 4, p e1001997 (2016)
BackgroundTKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated.Methods and findingsIn this single-arm phase 2 t
Externí odkaz:
https://doaj.org/article/5d847f2d4b774f4e93d2e3fad6719689
Autor:
Amanda E Semper, M Jana Broadhurst, Jade Richards, Geraldine M Foster, Andrew J H Simpson, Christopher H Logue, J Daniel Kelly, Ann Miller, Tim J G Brooks, Megan Murray, Nira R Pollock
Publikováno v:
PLoS Medicine, Vol 13, Iss 3, p e1001980 (2016)
Throughout the Ebola virus disease (EVD) epidemic in West Africa, field laboratory testing for EVD has relied on complex, multi-step real-time reverse transcription PCR (RT-PCR) assays; an accurate sample-to-answer RT-PCR test would reduce time to re
Externí odkaz:
https://doaj.org/article/aa573f1f7f5a497a891c1ad3ffc93a4b
Autor:
Thomas R Laws, Tinatin Kuchuloria, Nazibriola Chitadze, Stephen F Little, Wendy M Webster, Amanda K Debes, Salome Saginadze, Nikoloz Tsertsvadze, Mariam Chubinidze, Robert G Rivard, Shota Tsanava, Edward H Dyson, Andrew J H Simpson, Matthew J Hepburn, Nino Trapaidze
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0148713 (2016)
Several different human vaccines are available to protect against anthrax. We compared the human adaptive immune responses generated by three different anthrax vaccines or by previous exposure to cutaneous anthrax. Adaptive immunity was measured by E
Externí odkaz:
https://doaj.org/article/1cee2b6b032a4d4a878f6ef559889668
Autor:
David A. B. Dance, Mayfong Mayxay, Sayaphet Rattanavong, Manophab Luangraj, Paul N. Newton, Manivanh Vongsouvath, Ko Chang, Valy Keoluangkhot, Andrew J. H. Simpson, Viengmon Davong
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Although there has been an increasing incidence of bacteremia caused by extended-spectrum beta-lactamase (ESBL)–producing Enterobacteriaceae (ESBL-E) across South East Asia, there are sparse data from the Lao PDR, where laboratory capacity for anti
Autor:
Poda Sar, Clare L. Ling, Wanitda Watthanaworawit, Paul Turner, Robert Norton, François Nosten, Joy Silisouk, Vanaporn Wuthiekanun, Tamalee Roberts, Sena Sao, Direk Limmathurotsakul, Premjit Amornchai, Jill Hopkins, Andrew J. H. Simpson, Ian Gassiep, Matthew T. Robinson
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Microbiology
BMC Microbiology
Background Burkholderia pseudomallei is the bacterial causative agent of melioidosis, a difficult disease to diagnose clinically with high mortality if not appropriately treated. Definitive diagnosis requires isolation and identification of the organ
Autor:
Tamalee Roberts, Siribun Panapruksachat, Paul N. Newton, Soo Kai Ter, Andrew J. H. Simpson, Manivanh Vongsouvath, Sayaphet Rattanavong, Amphonesavanh Sengduangphachanh, Somsavanh Sihalath, Matthew T. Robinson
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Bloodstream infections cause substantial morbidity and mortality. However, despite clinical suspicion of such infections, blood cultures are often negative. We investigated blood cultures that were negative after 5 days of incubation for the presence