Výsledky vyhledávání - "A. J. Gunther"

Data from A Multistage Murine Breast Cancer Model Reveals Long-Lived Premalignant Clones Refractory to Parity-Induced Protection

Autor: Edward J. Gunther, Shelley A. Gestl, Shuo Li

Breast cancers evolve in a multistage process that can span decades after a carcinogenic exposure. It follows that long-lived precursor breast lesions persist in a subclinical state prior to completing malignant transformation, yet widely used breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::457acf8535b2aac4aa2a455f7e71313d
https://doi.org/10.1158/1940-6207.c.6547423.v1

Zobrazit plný text záznamu

Supplementary Video 9 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 2.3MB, Effects of mTor Inhibitor rapamycin on Ras-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and rapamycin i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d9a443fa1f9d9afa1a15ea458390be
https://doi.org/10.1158/0008-5472.22394366.v1

Zobrazit plný text záznamu

Data from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

The mammary ducts of humans and mice are comprised of two main mammary epithelial cell (MEC) subtypes: a surrounding layer of basal MECs and an inner layer of luminal MECs. Breast cancer subtypes show divergent clinical behavior that may reflect prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a61139985d10a4fb1ed71057f86ecec9
https://doi.org/10.1158/0008-5472.c.6504017.v1

Zobrazit plný text záznamu

Supplementary Video 3 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 2.1MB, ive cell imaging of H-RASG12V-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in 3D with Dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c21e141d8ff4b109b65c4da79e4e4f
https://doi.org/10.1158/0008-5472.22394387

Zobrazit plný text záznamu

Supplementary Video 8 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 1.6MB, Effects of Pi3k Inhibitor LY294002 on Ras-driven luminal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive luminalRas/GFP (MMTV-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and LY2940

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401f1cc30ebfaa9d45ed26796a6a6bec
https://doi.org/10.1158/0008-5472.22394369.v1

Zobrazit plný text záznamu

Supplementary Video 5 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 2.1MB, Effects of MEK Inhibitor PD0325901 on Ras-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and PD0325901 in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d1b59642b0e69f153057d9d15e5a0a
https://doi.org/10.1158/0008-5472.22394378.v1

Zobrazit plný text záznamu

Supplementary Video 1 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 2MB, Live cell imaging of a K5-rtTA/TGFP organoid. Representative video depicting an organoid prepared from a Dox-na�ve basalGFP (K5-rtTA/TGFP) mouse cultured in 3D with Dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ddb1c67bb0f1d069a417caa04e8ee3
https://doi.org/10.1158/0008-5472.22394396.v1

Zobrazit plný text záznamu

Supplementary Video 4 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 1.7MB, Live cell imaging of H-RASG12V-driven luminal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive luminalRas/GFP (MMTV-rtTA/TGFP/TRAS) mouse cultured in 3D with Dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531bb459276ce90b1cd04c26d40925d3
https://doi.org/10.1158/0008-5472.22394384.v1

Zobrazit plný text záznamu

Supplementary Video 2 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Autor: Edward J. Gunther, Adam B. Glick, Shelley A. Gestl, Jessica L. Mathers, Kristin A. Plichta

MOV file - 2.1MB, Live cell imaging of an MMTV-rtTA/TGFP organoids. Representative video depicting an organoid prepared from a Dox-naive luminalGFP (MMTV-rtTA/TGFP) mouse cultured in 3D with Dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e2ccf784f6767a3e02263a6f4ed4cf
https://doi.org/10.1158/0008-5472.22394390.v1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání