Zobrazeno 1 - 10
of 300
pro vyhledávání: '"A. J. Grundy"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A critical risk factor for head and neck squamous cell carcinoma (HNSCC), particularly of the oropharynx, and the response to radiotherapy is human papillomavirus (HPV) type-16/18 infection. Specifically, HPV-positive HNSCC display increased radiosen
Externí odkaz:
https://doaj.org/article/9bd37a3457fb4af39891aba90f136d8c
Autor:
Andrew M. K. Law, Laura Rodriguez de la Fuente, Thomas J. Grundy, Guocheng Fang, Fatima Valdes-Mora, David Gallego-Ortega
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Over 90% of potential anti-cancer drug candidates results in translational failures in clinical trials. The main reason for this failure can be attributed to the non-accurate pre-clinical models that are being currently used for drug development and
Externí odkaz:
https://doaj.org/article/95fb65fb5899476aa52b33cf93b7182e
Autor:
Emily J. Grundy, Taiba Suddek, Filippos T. Filippidis, Azeem Majeed, Sophie Coronini-Cronberg
Publikováno v:
Tobacco Induced Diseases, Vol 18, Iss July (2020)
Introduction There has been significant speculation regarding the association between the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pathogen, coronavirus disease (COVID-19) and smoking. We provide an overview of the available liter
Externí odkaz:
https://doaj.org/article/b36170e353a8402b9f71b1ed630cbc58
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/0ec86de194b7479ebb7bb33449e96200
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Externí odkaz:
https://doaj.org/article/445809e39596411894c241e66afcfafe
Autor:
Sara J. Grundy, Suzanne Maman, Lauren Graybill, Twambilile Phanga, Dhrutika Vansia, Tiyamike Nthani, Jennifer H. Tang, Linda-Gail Bekker, Audrey Pettifor, Nora E. Rosenberg
Publikováno v:
Journal of Pediatric and Adolescent Gynecology. 35:662-668
In sub-Saharan Africa, sexually active adolescent girls and young women (AGYW) experience high rates of intimate partner violence (IPV) and low levels of contraceptive use, but the effect of IPV on contraceptive use is not well understood.In the Girl
Autor:
Aline Mosnier, Guido Schmidt-Traub, Michael Obersteiner, Sarah Jones, Valeria Javalera-Rincon, Fabrice DeClerck, Marcus Thomson, Frank Sperling, Paula Harrison, Katya Pérez-Guzmán, Gordon Carlos McCord, Javier Navarro-Garcia, Raymundo Marcos-Martinez, Grace C. Wu, Jordan Poncet, Clara Douzal, Jan Steinhauser, Adrian Monjeau, Federico Frank, Heikki Lehtonen, Janne Rämö, Nicholas Leach, Charlotte E. Gonzalez-Abraham, Ranjan Kumar Ghosh, Chandan Jha, Vartika Singh, Zhaohai Bai, Xinpeng Jin, Lin Ma, Anton Strokov, Vladimir Potashnikov, Fernando Orduña-Cabrera, Rudolf Neubauer, Maria Diaz, Liviu Penescu, Efraín Antonio Domínguez, John Chavarro, Andres Pena, Shyam Basnet, Ingo Fetzer, Justin Baker, Hisham Zerriffi, René Reyes Gallardo, Brett Anthony Bryan, Michalis Hadjikakou, Hermann Lotze-Campen, Miodrag Stevanovic, Alison Smith, Wanderson Costa, A. H. F. Habiburrachman, Gito Immanuel, Odirilwe Selomane, Anne-Sophie Daloz, Robbie Andrew, Bob van Oort, Dative Imanirareba, Kiflu Gedefe Molla, Firew Bekele Woldeyes, Aline C. Soterroni, Marluce Scarabello, Fernando M. Ramos, Rizaldi Boer, Nurul Laksmi Winarni, Jatna Supriatna, Wai Sern Low, Andrew Chiah Howe Fan, François Xavier Naramabuye, Fidèle Niyitanga, Marcela Olguín, Alexander Popp, Livia Rasche, Charles Godfray, Jim W. Hall, Mike J. Grundy, Xiaoxi Wang
Publikováno v:
Sustainability Science. 18:335-345
There is an urgent need for countries to transition their national food and land-use systems toward food and nutritional security, climate stability, and environmental integrity. How can countries satisfy their demands while jointly delivering the re
Autor:
Joseph J. Palamar, Linda B. Cottler, Bruce A. Goldberger, Stevan Geoffrey Severtson, David J. Grundy, Janetta L. Iwanicki, Daniel Ciccarone
Publikováno v:
Am J Drug Alcohol Abuse
BACKGROUND: Fentanyl-related deaths continue to increase in the United States; however, most national studies focus on fatal overdose. More research, including data on nonfatal overdose, is needed. OBJECTIVE: We examined trends in characteristics of
Autor:
Catrina M Loucks, Kwangjin Park, Denise S Walker, Andrea H McEwan, Tiffany A Timbers, Evan L Ardiel, Laura J Grundy, Chunmei Li, Jacque-Lynne Johnson, Julie Kennedy, Oliver E Blacque, William Schafer, Catharine H Rankin, Michel R Leroux
Publikováno v:
eLife, Vol 8 (2019)
Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles of cilia in these neurons are poorly understood. To shed light into their functions, we stu
Externí odkaz:
https://doaj.org/article/187f16f490b2476e89b17a0470140d3f
Autor:
Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Chromosomal single-strand DNA breaks occur frequently and require repair to avoid disease outcomes. Here, the authors show that in bird cells, PARP3 accelerates this repair, and use structural biology and cell biology techniques to reveal details of
Externí odkaz:
https://doaj.org/article/f4adc148d44f418d9df058242e7f3bd6