Zobrazeno 1 - 10
of 2 539
pro vyhledávání: '"A. J. Gould"'
Autor:
Santosh Dhakal, Anna Yin, Marta Escarra-Senmarti, Zoe O. Demko, Nora Pisanic, Trevor S. Johnston, Maria Isabel Trejo-Zambrano, Kate Kruczynski, John S. Lee, Justin P. Hardick, Patrick Shea, Janna R. Shapiro, Han-Sol Park, Maclaine A. Parish, Christopher Caputo, Abhinaya Ganesan, Sarika K. Mullapudi, Stephen J. Gould, Michael J. Betenbaugh, Andrew Pekosz, Christopher D. Heaney, Annukka A. R. Antar, Yukari C. Manabe, Andrea L. Cox, Andrew H. Karaba, Felipe Andrade, Scott L. Zeger, Sabra L. Klein
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-15 (2024)
Abstract Background Critically ill hospitalized patients with COVID-19 have greater antibody titers than those with mild to moderate illness, but their association with recovery or death from COVID-19 has not been characterized. Methods In a cohort s
Externí odkaz:
https://doaj.org/article/f7ea6c1555904c5aa73e7df2ef8983ac
Autor:
Elizabeth A. Hamel, Jason B. Castro, Travis J. Gould, Robert Pellegrino, Zhiwei Liang, Liyah A. Coleman, Famesh Patel, Derek S. Wallace, Tanushri Bhatnagar, Joel D. Mainland, Richard C. Gerkin
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Advances in theoretical understanding are frequently unlocked by access to large, diverse experimental datasets. Our understanding of olfactory neuroscience and psychophysics remain years behind the other senses, in part because rich dataset
Externí odkaz:
https://doaj.org/article/ea1a4f0859b44cb093100427bc64b163
Autor:
Matthew J. Gould, Justin G. Clapp, Mark A. Haroldson, Cecily M. Costello, J. Joshua Nowak, Hans W. Martin, Michael R. Ebinger, Daniel D. Bjornlie, Daniel J. Thompson, Justin A. Dellinger, Matthew A. Mumma, Paul M. Lukacs, Frank T. van Manen
Publikováno v:
Global Ecology and Conservation, Vol 54, Iss , Pp e03133- (2024)
Long-term wildlife research and monitoring programs strive to maintain consistent data collections and analytical methods. Incorporating new techniques is important but can render data sets incongruent and limit their potential to discern trends in d
Externí odkaz:
https://doaj.org/article/ea3b926ac7454cb69db8b43f814d28ca
Publikováno v:
Frontiers in Sustainability, Vol 5 (2024)
Cell culture is a cornerstone of in vitro biological research. Whilst glassware was once commonplace in tissue culture facilities, in recent decades laboratories have moved towards a heavy reliance on single use plastics for routine procedures. Singl
Externí odkaz:
https://doaj.org/article/10a986928c564a78a3a10e6955a80bcd
Autor:
Smeeta Sinha, Sagar U. Nigwekar, Vincent Brandenburg, Lisa J. Gould, Thomas E. Serena, Sharon M. Moe, George R. Aronoff, Dinesh K. Chatoth, Jeffrey L. Hymes, Kevin J. Carroll, Gabriela Alperovich, Laurence H. Keller, Joan Perelló, Alex Gold, Glenn M. Chertow
Publikováno v:
EClinicalMedicine, Vol 75, Iss , Pp 102784- (2024)
Summary: Background: In the CALCIPHYX trial, we investigated hexasodium fytate, an inhibitor of vascular calcification, for the treatment of calcific uraemic arteriolopathy (calciphylaxis), a rare condition characterised by painful, non-healing skin
Externí odkaz:
https://doaj.org/article/ed79d86af030474a941e83bc9d1bd82e
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 731 (2024)
In this study, we investigated the antibacterial activity of octyl gallate (OG), an antioxidant food additive, against both Gram-positive and Gram-negative bacterial pathogens. OG demonstrated robust bactericidal activity against Gram-positive bacter
Externí odkaz:
https://doaj.org/article/fe49d56a47b2436db426759facccc924
Autor:
James Spicer, Bristi Basu, Ana Montes, Udai Banerji, Rebecca Kristeleit, Rowan Miller, Gareth J. Veal, Christopher J. Corrigan, Stephen J. Till, Mariangela Figini, Silvana Canevari, Claire Barton, Paul Jones, Sarah Mellor, Simon Carroll, Chris Selkirk, George Nintos, Vineet Kwatra, Ionut-Gabriel Funingana, Gary Doherty, Hannah J. Gould, Giulia Pellizzari, Mano Nakamura, Kristina M. Ilieva, Atousa Khiabany, Chara Stavraka, Jitesh Chauhan, Cheryl Gillett, Sarah Pinder, Heather J. Bax, Debra H. Josephs, Sophia N. Karagiannis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract All antibodies approved for cancer therapy are monoclonal IgGs but the biology of IgE, supported by comparative preclinical data, offers the potential for enhanced effector cell potency. Here we report a Phase I dose escalation trial (NCT025
Externí odkaz:
https://doaj.org/article/10c6fe5134614037a52da348794ee12d
Autor:
Daniel J. Gould, James A. Bailey, Tim Spelman, Samantha Bunzli, Michelle M. Dowsey, Peter F. M. Choong
Publikováno v:
Arthroplasty, Vol 5, Iss 1, Pp 1-15 (2023)
Abstract Background Thirty-day readmission is an increasingly important problem for total knee arthroplasty (TKA) patients. The aim of this study was to develop a risk prediction model using machine learning and clinical insight for 30-day readmissio
Externí odkaz:
https://doaj.org/article/c50f905816734ef598c706385dc53b90
Autor:
Jitesh Chauhan, Melanie Grandits, Lais C. G. F. Palhares, Silvia Mele, Mano Nakamura, Jacobo López-Abente, Silvia Crescioli, Roman Laddach, Pablo Romero-Clavijo, Anthony Cheung, Chara Stavraka, Alicia M. Chenoweth, Heng Sheng Sow, Giulia Chiaruttini, Amy E. Gilbert, Tihomir Dodev, Alexander Koers, Giulia Pellizzari, Kristina M. Ilieva, Francis Man, Niwa Ali, Carl Hobbs, Sara Lombardi, Daniël A. Lionarons, Hannah J. Gould, Andrew J. Beavil, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Eduardo Calonje, Julian Downward, Frank O. Nestle, Sophia Tsoka, Debra H. Josephs, Philip J. Blower, Panagiotis Karagiannis, Katie E. Lacy, James Spicer, Sophia N. Karagiannis, Heather J. Bax
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Outcomes for half of patients with melanoma remain poor despite standard-of-care checkpoint inhibitor therapies. The prevalence of the melanoma-associated antigen chondroitin sulfate proteoglycan 4 (CSPG4) expression is ~70%, therefore effec
Externí odkaz:
https://doaj.org/article/eeac938a111045e186e031edbfe48da6
Autor:
Francis K. Fordjour, Sarah Abuelreich, Xiaoman Hong, Emeli Chatterjee, Valeria Lallai, Martin Ng, Andras Saftics, Fengyan Deng, Natacha Carnel-Amar, Hiroaki Wakimoto, Kazuhide Shimizu, Malia Bautista, Tuan Anh Phu, Ngan K. Vu, Paige C. Geiger, Robert L. Raffai, Christie D. Fowler, Saumya Das, Lane K. Christenson, Tijana Jovanovic-Talisman, Stephen J. Gould
Publikováno v:
Extracellular Vesicle, Vol 2, Iss , Pp 100030- (2023)
Exosomes are small extracellular vesicles (sEVs) of ∼30–150 nm in diameter that are enriched in exosome marker proteins and play important roles in health and disease. To address large unanswered questions regarding exosome biology in vivo, we cr
Externí odkaz:
https://doaj.org/article/230a674d538b4be3b987c15fb35da4df