Zobrazeno 1 - 10
of 406
pro vyhledávání: '"A. J. Ghio"'
Autor:
Aiman Abzhanova, Jon Berntsen, Edward R. Pennington, Lisa Dailey, Syed Masood, Ingrid George, Nina Warren, Joseph Martin, Michael D. Hays, Andrew J. Ghio, Jason P. Weinstein, Yong Ho Kim, Earl Puckett, James M. Samet
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Wildland fires contribute significantly to the ambient air pollution burden worldwide, causing a range of adverse health effects in exposed populations. The toxicity of woodsmoke, a complex mixture of gases, volatile organic compounds, and p
Externí odkaz:
https://doaj.org/article/fee5db2f59f84053b61951a7bb9daed5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposu
Externí odkaz:
https://doaj.org/article/7c012955223442c1a0c974013d4c0b79
Publikováno v:
Clinical Pathology, Vol 16 (2023)
Background: Peribronchiolar metaplasia (PBM) is considered a reaction to injury characterized by the proliferation of bronchiolar epithelium into immediately adjacent alveolar walls. While an association of PBM with diffuse interstitial lung diseases
Externí odkaz:
https://doaj.org/article/36e3ac796eb34b8a9d50cc4ddf60ef66
Autor:
Cesare Saltini, Naweed Mohammad, Yan Xin, Rodolfo Alvarado, Andrew J. Ghio, Craig G. Moneypenny, Alberto Riva, Dongtao Fu, Tammy Flagg, Giovanni F.A. Saltini, Ivan Arisi, Kristianna M. Fredenburg, Yang Zhang, Jorge E. Lascano, Mark Brantly
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Background Animal models using intratracheal instillation show that elastase, unopposed by α1-antitrypsin (AAT), causes alveolar damage and haemorrhage associated with emphysematous changes. The aim of the present study was to characterise any relat
Externí odkaz:
https://doaj.org/article/2f81028d5bd642ba875076d2f6cc0216
Autor:
Rahul G. Sangani, Vishal Deepak, Andrew J. Ghio, Michael J. Forte, Rafia Zulfikar, Zalak Patel, Austin King, Esra Alshaikhnassir, Ghulam Abbas, Jeffrey Vos
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Cigarette smoking is a risk factor for interstitial lung abnormalities (ILAs) and interstitial lung diseases (ILDs). Investigation defining the relationships between ILAs/ILDs and clinical, radiographic, and pathologic findings in
Externí odkaz:
https://doaj.org/article/7aaf2ef829a341049746956504b63c4b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12390 (2023)
Theories of disease pathogenesis following asbestos exposure have focused on the participation of iron. After exposure, an open network of negatively charged functional groups on the fiber surface complexes host metals with a preference for iron. Com
Externí odkaz:
https://doaj.org/article/54c137b6fcd94454aa6c26ebcb972088
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background Inhalation of common air pollutants such as diesel and biodiesel combustion products can induce vascular changes in humans which may contribute to increased mortality and morbidity associated with fine particulate matter exposures
Externí odkaz:
https://doaj.org/article/599dd8d750fd4333b159da39e355dca3
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease. 18:431-446
Rahul G Sangani,1 Vishal Deepak,1 Javeria Anwar,1 Zalak Patel,2 Andrew J Ghio3 1Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, West Virginia University, Morgantown, WV, USA; 2Department of Radiology, West Virginia Uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2e94b1483a760c9b8ce300d52c911b
https://doi.org/10.2147/copd.s397667
https://doi.org/10.2147/copd.s397667
Autor:
Andrew J. Ghio, Genee S. Smith, Stephanie DeFlorio-Barker, Kyle P. Messier, Edward Hudgens, Mark S. Murphy, Jean-Marie Maillard, Jason E. Stout, Elizabeth D. Hilborn
Publikováno v:
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 17, Iss , Pp - (2019)
The American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA) have provided guidelines to assist in the accurate diagnosis of lung disease caused by nontuberculous mycobacteria (NTM). These microbiologic, radiographic, and cli
Externí odkaz:
https://doaj.org/article/6532f459b83b4035b3195a536c535ba5
Autor:
Natascha A. Wolff, Michael D. Garrick, Lin Zhao, Laura M. Garrick, Andrew J. Ghio, Frank Thévenod
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Much of iron and manganese metabolism occurs in mitochondria. Uptake of redox-active iron must be tightly controlled, but little is known about how metal ions enter mitochondria. Recently, we established that the divalent metal transporter 1
Externí odkaz:
https://doaj.org/article/c28f4d75b2874b9d9cddc1e25c2f7f68