Zobrazeno 1 - 10
of 67
pro vyhledávání: '"A. J. Georgopoulos"'
Autor:
Stephanie L Swift, Guillermo C Rivera, Vincent Dussupt, Regina M Leadley, Lucy C Hudson, Corrina Ma de Ridder, Robert Kraaij, Julie E Burns, Norman J Maitland, Lindsay J Georgopoulos
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65557 (2013)
Gene therapy represents an attractive strategy for the non-invasive treatment of prostate cancer, where current clinical interventions show limited efficacy. Here, we evaluate the use of the insect virus, baculovirus (BV), as a novel vector for human
Externí odkaz:
https://doaj.org/article/2b44e3f412824eb893a9ff1215f03de6
Autor:
Norman J. Maitland, Alastair Droop, Katrin Tiemann, Helen J. Rippon, Davide Pellacani, Lindsay J. Georgopoulos, Guillermo C. Rivera-Gonzalez
Publikováno v:
Nucleic Acids Research
In the human prostate, expression of prostate-specific genes is known to be directly regulated by the androgen–induced stimulation of the androgen receptor (AR). However, less is known about the expression control of the prostate-restricted TGM4 (h
Autor:
Guillermo C. Rivera-Gonzalez, Vincent Dussupt, Norman J. Maitland, Lindsay J. Georgopoulos, Stephanie L. Swift
Publikováno v:
Journal of Invertebrate Pathology. 107:S59-S70
Prostate cancer is the most commonly diagnosed cancer in ageing men in the western world. While the primary cancers can be treated with androgen ablation, radiotherapy and surgery, recurrent castration resistant cancers have an extremely poor prognos
Autor:
Karen F. Chambers, Lindsay J. Georgopoulos, Corrina M.A. de Ridder, Magnus Essand, Angelika Danielsson, Chris H. Bangma, Regina M. Leadley, Helen Evans, Wytske M. van Weerden, Martha Simpson-Holley, Robert Kraaij, Norman J. Maitland
Publikováno v:
Human Gene Therapy, 21(7), 815-827. Mary Ann Liebert Inc.
Destruction of cancer cells by genetically modified viral and nonviral vectors has been the aim of many research programs. The ability to target cytotoxic gene therapies to the cells of interest is an essential prerequisite, and the treatment has alw
Autor:
George J. Georgopoulos, Walid Hejazi
Publikováno v:
International Review of Economics & Finance. 18:341-350
The large correlation between domestic savings and investment is well documented and is known as the Feldstein–Horioka puzzle. We demonstrate that estimates of the FH coefficients using the standard framework are biased upward in the presence of hi
Autor:
George J. Georgopoulos, Walid Hejazi
Publikováno v:
Journal of Economics and Business. 61:1-33
The two general channels by which monetary policy impacts output are the neo-classical cost of capital channel and the credit channel. This paper decomposes the output response to a change in the stance of monetary policy to each of these channels. W
Autor:
George J. Georgopoulos
Publikováno v:
Atlantic Economic Journal. 36:315-332
This paper examines exchange rate and trade data to determine whether J-curve effects have occurred for Canada in recent history. With a unique set of data on import and export volumes, the response of the trade balance and its components to exchange
Autor:
George J. Georgopoulos
Publikováno v:
Canadian Journal of Economics/Revue canadienne d'économique. 41:450-474
Theoretical and empirical studies investigating the relationship between the exchange rate and FDI have generated mixed results. Using bilateral Canadian-U.S. industry level count data on cross-border mergers and acquisitions (M&As) and conditioning
Publikováno v:
Canadian Journal of Economics/Revue canadienne d'économique. 40:1008-1032
Although recent research has led to a deeper understanding of the factors determining yields on long term Canada bonds, there has been little corresponding work on provincial bonds. This is despite the fact that unlike the US state bond market, provi
Autor:
George J. Georgopoulos
Publikováno v:
The Quarterly Review of Economics and Finance. 46:513-529
Traditional studies estimating the long-run demand for real money in Canada assume that narrow money, or M1, bears zero interest. However if implicit interest has been paid, such interest should be taken into account in determining the opportunity co