Zobrazeno 1 - 10
of 17
pro vyhledávání: '"A. J. Gaw"'
Autor:
J. GAW
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp S282- (2021)
Externí odkaz:
https://doaj.org/article/a13052293591457894e7233823c79169
Autor:
Alasdair J. Gaw
Translational Science demands the integration of all the biomedical sciences to optimise delivery of the objective of any drug discovery project: demonstration of an effect of new medical entities in patients. This chapter will address some key estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4433ab6cbf143befa09cb1c2a93bc3
https://doi.org/10.1039/9781782621836-00350
https://doi.org/10.1039/9781782621836-00350
Publikováno v:
European Journal of Pharmacology. 179:35-44
In the sheep cerebral vasculature 5-hydroxytryptamine (5-HT) caused a contraction of which ketanserin was found to be an effective antagonist (Basilar artery, pA2 = 9.33 +/- 0.16; middle cerebral artery, pA2 = 9.19 +/- 0.16; pial artery, pA2 = 9.47 +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3bcc8d644ed75ffc897bb54adc6cf6
https://doi.org/10.1016/0014-2999(90)90399-q
https://doi.org/10.1016/0014-2999(90)90399-q
1. The cardiovascular actions of cholecystokinin and related peptides were investigated in the pithed rat. The receptors and the mechanisms involved in these experiments were characterized. 2. Sulphated cholecystokinin octapeptide (sCCK-8, 0.1-100 nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d998e348dd77d3dd4c06e2df465c85b9
https://europepmc.org/articles/PMC1908495/
https://europepmc.org/articles/PMC1908495/
Publikováno v:
Alimentary pharmacologytherapeutics. 9(2)
SUMMARY Aims: To examine the effects of a pepsin inhibitor, pepstatin-A, a long acting H2-receptor blocker, loxtidine, exogenous pepsin and exogenous acid against indomethacin-induced antral ulceration in the rat. Results: Indomethacin (60 mg/kg s.c.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93e517817a1f8cc3402815f1ccc836f
https://pubmed.ncbi.nlm.nih.gov/7605857
https://pubmed.ncbi.nlm.nih.gov/7605857
Autor:
John A. Bevan, A J Gaw
Publikováno v:
Stroke. 24(1)
The flow-induced relaxation of a branch of the rabbit middle cerebral artery was examined to determine if an endothelial-independent as well as -dependent component occurs in pial as well as systemic small arteries and the possible role of products o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2cb0d6a5a1403f3c26a22fa0b01cfa
https://pubmed.ncbi.nlm.nih.gov/8418532
https://pubmed.ncbi.nlm.nih.gov/8418532
1. Perivascular nerves of the sheep middle cerebral artery show immunoreactivity for both vasoactive intestinal polypeptide (VIP) and calcitonin gene-related peptide (CGRP). 2. Rings of endothelium-denuded sheep middle cerebral artery precontracted w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9377b4d2f76f61118d2101ec3e33a8c
https://europepmc.org/articles/PMC1917941/
https://europepmc.org/articles/PMC1917941/
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 10(3)
In ring sections of the sheep middle cerebral artery, electrical field stimulation elicits a complex response due to the simultaneous release of vasodilator and vasoconstrictor neurotransmitters. Haemolysate abolishes the relaxant effects of the vaso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc6cfde868b2a515c865b001af9b93
https://pubmed.ncbi.nlm.nih.gov/1970342
https://pubmed.ncbi.nlm.nih.gov/1970342
Autor:
Alasdair J. Gaw, Roger M. Wadsworth
Publikováno v:
British Journal of Pharmacology. 98:741-746
1. The responsiveness to noradrenaline was characterized in cerebral arteries from the sheep, since this species was large enough to permit a comparison of arteries from different parts of the cerebral vasculature. 2. Noradrenaline caused contraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2796687dc83f5ba1a16082a721df1b6
https://doi.org/10.1111/j.1476-5381.1989.tb14601.x
https://doi.org/10.1111/j.1476-5381.1989.tb14601.x
Autor:
William J. Gaw, Robert L. Scott
Publikováno v:
The Journal of Chemical Thermodynamics. 3:335-345
Recent theoretical and experimental studies suggest that (∂2V/∂x2)T, p and (∂2H/∂x2T, p vanish at the critical solution point. We report dilatometric measurements of volume changes in the system n-C6H14 + n-C6F14 at 21 compositions and eight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f09a8d5b8105629d1e0f8b17cd1abe
https://doi.org/10.1016/s0021-9614(71)80050-2
https://doi.org/10.1016/s0021-9614(71)80050-2