Zobrazeno 1 - 10
of 68
pro vyhledávání: '"A. J. Drake-Holland"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 3 (2016)
Hyponatremia is the most common electrolyte abnormality, and is often neglected, especially in elderly and seemingly terminal patients. Hyponatremia can be asymptomatic or can cause symptoms ranging from nausea and lethargy to convulsions and coma. T
Externí odkaz:
https://doaj.org/article/2a8cad8912704591917a37e661b3eb0c
Autor:
Jochen Schaefer, Angela J. Drake-Holland, Brigitte Lohff, Mark I. M. Noble, Johann P. Kuhtz-Buschbeck
Publikováno v:
Journal of Molecular and Cellular Cardiology. 119:96-103
In the late 19th century, German physiologist Otto Frank (1865-1944) embarked on a near life-long research program of laying down the mathematical, methodological, and theoretical foundations in order to understand and define the performance of the h
Publikováno v:
Journal of Hematology and Clinical Research. 1:019-025
An enquiry into the lack of attention awarded to serotonin antagonism in the treatment of arterial thrombosis revealed that the mode of action of serotonin and its platelet receptor antagonists was an action upon thrombus growth, and not, as with oth
Coronary Vessel Supersensitivity to Noradrenaline in the Presence of Chronic Sympathetic Denervation
Publikováno v:
Journal of Cardiac Disorders and Therapy. 1
Autor:
Mark I. M. Noble, Brigitte Lohff, Jochen Schaefer, Johann P. Kuhtz-Buschbeck, Angela J. Drake-Holland
Publikováno v:
Journal of Molecular and Cellular Cardiology. 123:58
Publikováno v:
The British Journal of Diabetes & Vascular Disease. 10:66-70
The vascular glycocalyx is a gel layer between endothelium and the blood, 0.5 µm thick. Evidence is presented from published studies to indicate that hyperglycaemia causes damage to the vascular glycocalyx. This damage results in microalbuminuria, e
Publikováno v:
Cardiovascular & Hematological Disorders-Drug Targets. 9:118-123
The process of atherothrombosis is known to involve endothelial pathology (first drug target), plaque formation (second drug target) and thrombosis (third drug target). However it has recently been postulated that, even before endothelial pathology o
Publikováno v:
Vascular Disease Prevention. 2:67-76
Autor:
Richard Cornelussen, Mark I. M. Noble, Johannes H. G. M. van Beek, Frits W. Prinzen, Angela J. Drake-Holland, Frans J. J. de Kanter, Patricia A. C. Specht, David J. C. Alders
Publikováno v:
Experimental Physiology. 92:541-548
Myocardial blood flow and oxygen consumption are heterogeneously distributed. Perfusion and myocardial oxygen consumption are closely correlated in the normal heart. It is unknown how this metabolism–perfusion relation is influenced by sympathetic
Publikováno v:
The Journal of Physiology. 573:133-145
Clinical hyperglycaemia affects vascular endothelial function, but the effect on shear stress-induced arterial dilatation has not yet been established. We hypothesized that hyperglycaemia would inhibit this response via impaired glycocalyx mechanotra