Zobrazeno 1 - 10
of 841
pro vyhledávání: '"A. J. Cleare"'
Autor:
L. Marwood, R. Taylor, K. Goldsmith, R. Romeo, R. Holland, A. Pickles, J. Hutchinson, D. Dietch, A. Cipriani, R. Nair, M.-J. Attenburrow, A. H. Young, J. Geddes, R. H. McAllister-Williams, A. J. Cleare
Publikováno v:
BMC Psychiatry, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Approximately 30–50% of patients with major depressive disorder can be classed as treatment resistant, widely defined as a failure to respond to two or more adequate trials of antidepressants in the current episode. Treatment re
Externí odkaz:
https://doaj.org/article/a750710ba1b645078f08c6e7590650b4
Autor:
Mekdes Demissie, Rahel Birhane, Charlotte Hanlon, Tigist Eshetu, Girmay Medhin, Abebaw Minaye, Kassahun Habtamu, Anthony J. Cleare, Barkot Milkias, Martin Prince, Abebaw Fekadu
Publikováno v:
BJPsych Open, Vol 10 (2024)
Background The poor detection of depression in primary healthcare (PHC) in low- and middle-income countries continues to threaten the plan to scale up mental healthcare coverage. Aims To describe the process followed to develop an intervention packa
Externí odkaz:
https://doaj.org/article/f84ec1c2681a427d95927b5f12f3105b
Autor:
Lindsey Marwood, Jess Kerr-Gaffney, Toby Wise, Rebecca Strawbridge, Adam M. Perkins, Anthony J. Cleare
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Excessive negative self-referential processing plays an important role in the development and maintenance of major depressive disorder (MDD). Current measures of self-reflection are limited to self-report questionnaires and invoking imagin
Externí odkaz:
https://doaj.org/article/89dd3982886d474fb55e3bf8cdcece23
Autor:
Abebaw Fekadu, Mekdes Demissie, Rahel Birhane, Girmay Medhin, Tesera Bitew, Maji Hailemariam, Abebaw Minaye, Kassahun Habtamu, Barkot Milkias, Inge Petersen, Vikram Patel, Anthony J. Cleare, Rosie Mayston, Graham Thornicroft, Atalay Alem, Charlotte Hanlon, Martin Prince
Publikováno v:
Systematic Reviews, Vol 11, Iss 1, Pp 1-10 (2022)
Abstract Background Depression is one of the commonest mental disorders in primary care but is poorly identified. The objective of this review was to determine the level of detection of depression by primary care clinicians and its determinants in st
Externí odkaz:
https://doaj.org/article/0fd1209fdf0c44d39917c7193e35c010
Autor:
Giulia Lombardo, Maria Antonietta Nettis, Caitlin Hastings, Zuzanna Zajkowska, Nicole Mariani, Naghmeh Nikkheslat, Courtney Worrell, Daniela Enache, Anna McLaughlin, Melisa Kose, Anna Bogdanova, Luca Sforzini, Anthony J. Cleare, Allan H. Young, Paola Dazzan, Valeria Mondelli, Carmine M. Pariante
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100561- (2022)
Background: Inflammation is a well-known risk factor for depression. Specifically, patients who do not respond to antidepressant treatment show higher levels of inflammatory biomarkers compared with responders. Thus, several studies have investigated
Externí odkaz:
https://doaj.org/article/e3b28fd5a3d34d8ab59e01f1dd9f3ce9
Autor:
Kalypso Markopoulou, Susanne Fischer, Andrew Papadopoulos, Lucia Poon, Lena J. Rane, Abebaw Fekadu, Anthony J. Cleare
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis has been demonstrated in patients with treatment-resistant depression, although studies have often conflated patients with unipolar and bipolar depression. This is problema
Externí odkaz:
https://doaj.org/article/da1465cee7e14dac9c7a352b4eda8a01
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
The mystical experience is a potential psychological mechanism to influence outcome in psychedelic therapy. It includes features such as oceanic boundlessness, ego dissolution, and universal interconnectedness, which have been closely linked to both
Externí odkaz:
https://doaj.org/article/69120568daa74d1f95735f6ba4a87bf6
Autor:
Lindsey Marwood, Toby Wise, Jess Kerr-Gaffney, Rebecca Strawbridge, Steve C R Williams, Anthony J Cleare, Adam Perkins
Publikováno v:
Personality Neuroscience, Vol 5 (2022)
Threat avoidance is a prominent symptom of affective disorders, yet its biological basis remains poorly understood. Here, we used a validated task, the Joystick Operated Runway Task (JORT), combined with fMRI, to explore whether abnormal function in
Externí odkaz:
https://doaj.org/article/4ccba67b7cf74446bdcae004551a0f65
Publikováno v:
BJPsych Open, Vol 7 (2021)
Background Treatment-resistant depression (TRD) is classically defined according to the number of suboptimal antidepressant responses experienced, but multidimensional assessments of TRD are emerging and may confer some advantages. Patient characteri
Externí odkaz:
https://doaj.org/article/d29d0ac040164ca8b0d51d80a0d6c418
Autor:
Elana Day, Rupal Shah, Rachael W. Taylor, Lindsey Marwood, Kimberley Nortey, Jade Harvey, R. Hamish McAllister-Williams, John R. Geddes, Alvaro Barrera, Allan H. Young, Anthony J. Cleare, Rebecca Strawbridge
Publikováno v:
BJPsych Open, Vol 7 (2021)
Background Individuals with treatment-resistant depression (TRD) experience a high burden of illness. Current guidelines recommend a stepped care approach for treating depression, but the extent to which best-practice care pathways are adhered to is
Externí odkaz:
https://doaj.org/article/e7a1c09509a940e886d3bc574793cf3f