Zobrazeno 1 - 10
of 468
pro vyhledávání: '"A. J. Chuck"'
Three-Dimensional (3D) chromatin interactions, such as enhancer-promoter interactions (EPIs), loops, Topologically Associating Domains (TADs), and A/B compartments play critical roles in a wide range of cellular processes by regulating gene expressio
Externí odkaz:
http://arxiv.org/abs/2403.03231
Autor:
Villafaña, Lizvette, Williams, Peter R., Treu, Tommaso, Brewer, Brendon J., Barth, Aaron J., U, Vivian, Bennert, Vardha N., Guo, Hengxiao, Bentz, Misty C., Canalizo, Gabriela, Filippenko, Alexei V., Gates, Elinor, Joner, Michael D., Malkan, Matthew A., Woo, Jong-Hak, Abolfathi, Bela, Bohn, Thomas, Bostroem, K. Azalee, Brandel, Andrew, Brink, Thomas G., Channa, Sanyum, Cosens, Maren, Donohue, Edward, Halevi, Goni, Hood, Carol E., Horst, J. Chuck, de Kouchkovsky, Maxime, Kuhn, Benjamin, Leonard, Douglas C., Michel, Raul, Olaes, Melanie Kae B., Park, Daeseong, Runco, Jordan N., Sexton, Remington O., Shivvers, Isaac, Spencer, Chance L., Stahl, Benjamin E., Stegman, Samantha, Walsh, Jonelle L., Zheng, WeiKang
We combine our dynamical modeling black hole mass measurements from the Lick AGN Monitoring Project 2016 sample with measured cross-correlation time lags and line widths to recover individual scale factors, f, used in traditional reverberation mappin
Externí odkaz:
http://arxiv.org/abs/2304.06764
A triple hormone receptor ER, AR, and VDR signature is a robust prognosis predictor in breast cancer
Autor:
Mohamed Omar, J. Chuck Harrell, Rulla Tamimi, Luigi Marchionni, Cihat Erdogan, Harikrishna Nakshatri, Tan A. Ince
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Despite evidence indicating the dominance of cell-of-origin signatures in molecular tumor patterns, translating these genome-wide patterns into actionable insights has been challenging. This study introduces breast cancer cell-of-
Externí odkaz:
https://doaj.org/article/8a2eb70994dd4c63a4786f5a0770dfac
Autor:
Julia E. Altman, Amy L. Olex, Emily K. Zboril, Carson J. Walker, David C. Boyd, Rachel K. Myrick, Nicole S. Hairr, Jennifer E. Koblinski, Madhavi Puchalapalli, Bin Hu, Mikhail G. Dozmorov, X. Steven Chen, Yunshun Chen, Charles M. Perou, Brian D. Lehmann, Jane E. Visvader, J. Chuck Harrell
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Breast cancer's complex transcriptional landscape requires an improved understanding of cellular diversity to identify effective treatments. The study of genetic variations among breast cancer subtypes at single‐cell resolution
Externí odkaz:
https://doaj.org/article/d0c391dda0a74b8395d749dfd6add293
Autor:
James Smith, Amy Pilsbury, Vinod Kumar, Eleni E. Karamerou, Christopher J. Chuck, Leopoldo Herrera-Rodriguez, Julio V. Suarez, Michael J. Allen
Publikováno v:
Phycology, Vol 4, Iss 1, Pp 53-64 (2024)
Mass Sargassum inundations have created opportunities for readily available biomass to be used as a crop enrichment application. However, the heavy metal contents of Sargassum pose serious concerns for crop administration and subsequent human consump
Externí odkaz:
https://doaj.org/article/50aef929234a4df29e438c753292d988
Autor:
Villafaña, Lizvette, Williams, Peter R., Treu, Tommaso, Brewer, Brendon J., Barth, Aaron J., U, Vivian, Bennert, Vardha N., Vogler, H. Alexander, Guo, Hengxiao, Bentz, Misty C., Canalizo, Gabriela, Filippenko, Alexei V., Gates, Elinor, Hamann, Frederick, Joner, Michael D., Malkan, Matthew A., Woo, Jong-Hak, Abolfathi, Bela, Abramson, L. E., Armen, Stephen F., Bae, Hyun-Jin, Bohn, Thomas, Boizelle, Benjamin D., Bostroem, Azalee, Brandel, Andrew, Brink, Thomas G., Channa, Sanyum, Cooper, M. C., Cosens, Maren, Donohue, Edward, Fillingham, Sean P., Gonzalez-Buitrago, Diego, Halevi, Goni, Halle, Andrew, Hood, Carol E., Horne, Keith, Horst, J. Chuck, de Kouchkovsky, Maxime, Kuhn, Benjamin, Kumar, Sahana, Leonard, Douglas C., Loveland, Donald, Manzano-King, Christina, McHardy, Ian, Michel, Raul, Olaes, Melanie Kae B., Park, Daeseong, Park, Songyoun, Pei, Liuyi, Ross, Timothy W., Runco, Jordan N., Samuel, Jenna, Sanchez, Javier, Scott, Bryan, Sexton, Remington O., Shin, Jaejin, Shivvers, Isaac, Spencer, Chance L., Stahl, Benjamin E., Stegman, Samantha, Stomberg, Isak, Valenti, Stefano, Walsh, Jonelle L., Yuk, Heechan, Zheng, WeiKang
We have modeled the velocity-resolved reverberation response of the H\b{eta} broad emission line in nine Seyfert 1 galaxies from the Lick Active Galactic Nucleus (AGN) Monitioring Project 2016 sample, drawing inferences on the geometry and structure
Externí odkaz:
http://arxiv.org/abs/2203.15000
Autor:
U, Vivian, Barth, Aaron J., Vogler, H. Alexander, Guo, Hengxiao, Treu, Tommaso, Bennert, Vardha N., Canalizo, Gabriela, Filippenko, Alexei V., Gates, Elinor, Hamann, Frederick, Joner, Michael D., Malkan, Matthew A., Pancoast, Anna, Williams, Peter R., Woo, Jong-Hak, Abolfathi, Bela, Abramson, L. E., Armen, Stephen F., Bae, Hyun-Jin, Bohn, Thomas, Boizelle, Benjamin D., Bostroem, Azalee, Brandel, Andrew, Brink, Thomas G., Channa, Sanyum, Cooper, M. C., Cosens, Maren, Donohue, Edward, Fillingham, Sean P., González-Buitrago, Diego, Halevi, Goni, Halle, Andrew, Hood, Carol E., Horne, Keith, Horst, J. Chuck, de Kouchkovsky, Maxime, Kuhn, Benjamin, Kumar, Sahana, Leonard, Douglas C., Loveland, Donald, Manzano-King, Christina, McHardy, Ian, Michel, Raúl, Olaes, Melanie Kae B., Park, Daeseong, Park, Songyoun, Pei, Liuyi, Ross, Timothy W., Runco, Jordan N., Samuel, Jenna, Sánchez, Javier, Scott, Bryan, Sexton, Remington O., Shin, Jaejin, Shivvers, Isaac, Spencer, Chance L., Stahl, Benjamin E., Stegman, Samantha, Stomberg, Isak, Valenti, Stefano, Villafaña, L., Walsh, Jonelle L., Yuk, Heechan, Zheng, WeiKang
We carried out spectroscopic monitoring of 21 low-redshift Seyfert 1 galaxies using the Kast double spectrograph on the 3-m Shane telescope at Lick Observatory from April 2016 to May 2017. Targeting active galactic nuclei (AGN) with luminosities of {
Externí odkaz:
http://arxiv.org/abs/2111.14849
Autor:
Holly A. Byers, Amy N. Brooks, Janakiram R. Vangala, Jacqueline M. Grible, Alex Feygin, Charles V. Clevenger, J. Chuck Harrell, Senthil K. Radhakrishnan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Proteasomes are multi-subunit complexes that specialize in protein degradation. Cancer cells exhibit a heightened dependence on proteasome activity, presumably to support their enhanced proliferation and other cancer-related characteristics.
Externí odkaz:
https://doaj.org/article/b82055ba10214bee8c5bbb1360cff8ce
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Autor:
Mikhail G. Dozmorov, Maggie A. Marshall, Narmeen S. Rashid, Jacqueline M. Grible, Aaron Valentine, Amy L. Olex, Kavita Murthy, Abhijit Chakraborty, Joaquin Reyna, Daniela Salgado Figueroa, Laura Hinojosa-Gonzalez, Erika Da-Inn Lee, Brittany A. Baur, Sushmita Roy, Ferhat Ay, J. Chuck Harrell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Changes in the three-dimensional (3D) structure of the genome are an emerging hallmark of cancer. Cancer-associated copy number variants and single nucleotide polymorphisms promote rewiring of chromatin loops, disruption of topologically ass
Externí odkaz:
https://doaj.org/article/1d1cdc9046944ac6ba8d721377b361eb