Zobrazeno 1 - 10
of 118
pro vyhledávání: '"A. J. Brinkley"'
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 18, Iss 1, Pp 1-23 (2021)
Abstract Background Physical activity is a modifiable risk factor for health and wellbeing, all-cause mortality and healthy aging. However, for middle- to older-age females less is known about the benefits of sports participation on these outcomes. F
Externí odkaz:
https://doaj.org/article/1367128e7f5545ca8ec9b9f600981d00
Autor:
Nader H. Mahmoudzadeh, Yasaman Heidarian, Jason P. Tourigny, Alexander J. Fitt, Katherine Beebe, Hongde Li, Arthur Luhur, Kasun Buddika, Liam Mungcal, Anirban Kundu, Robert A. Policastro, Garrett J. Brinkley, Gabriel E. Zentner, Travis Nemkov, Robert Pepin, Geetanjali Chawla, Sunil Sudarshan, Aylin R. Rodan, Angelo D'Alessandro, Jason M. Tennessen
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102013- (2024)
Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell
Externí odkaz:
https://doaj.org/article/c959551a1a6c44d4a4238d794febab0c
Publikováno v:
Therapeutic Advances in Urology, Vol 14 (2022)
The decision whether to undergo prostate biopsy must be carefully weighed. Nomograms have widely been utilized as risk calculators to improve the identification of prostate cancer by weighing several clinical factors. The recent inclusion of multipar
Externí odkaz:
https://doaj.org/article/f26712b564394ad5a908697587d996b0
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
Purpose:Elevation of L-2-hydroxylgutarate (L-2-HG) in renal cell carcinoma (RCC) is due in part to reduced expression of L-2-HG dehydrogenase (L2HGDH). However, the contribution of L-2-HG to renal carcinogenesis and insight into the biochemistry and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8a7332380cb20b611f1b22ee0bd469
https://doi.org/10.1158/1078-0432.c.6526647
https://doi.org/10.1158/1078-0432.c.6526647
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
Supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719fb94193e947bf4afe516bdbef5530
https://doi.org/10.1158/1078-0432.22467453.v1
https://doi.org/10.1158/1078-0432.22467453.v1
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
This table reports L2HGDH mRNA expression as a function of 14q Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa8964eb6ea55a5ff3bb2bfc45f3fdf
https://doi.org/10.1158/1078-0432.22467456.v1
https://doi.org/10.1158/1078-0432.22467456.v1
Autor:
Anirban Kundu, Garrett J. Brinkley, Hyeyoung Nam, Suman Karki, Richard Kirkman, Hayley Widden, Michelle Johnson, Juan Liu, Yasaman Heidarian, Nader Mahmoudzadeh, Devin Absher, Han-Fei Ding, David Crosman, William J. Placzek, Jason Locasale, Dinesh Rakheja, Victor Darley-Usmar, Jason Tennessen, Sunil Sudarshan
Publikováno v:
Cancer Research. 83:3705-3705
The oncometabolite, L-2-hydroxyglutarate (L-2HG) is elevated in the most common form of renal cell carcinoma-RCC (clear cell histology) and promotes tumor progression. L-2HG is structurally similar to α-ketoglutarate (α-KG). Therefore, L-2HG can co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b6526d5cd6f5e82483bd7747677c28
https://doi.org/10.1158/1538-7445.am2023-3705
https://doi.org/10.1158/1538-7445.am2023-3705
Autor:
G. J. Mann, A. J Brinkley
Publikováno v:
Qualitative Research in Sport, Exercise and Health. 13:990-1005
Physiological, psychological and social risk factors influence the health and wellbeing of military personnel and units. Whilst evidence has investigated employment within the regular military, the...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abe5786cc7a97beeefc93d4f2950fb40
https://doi.org/10.1080/2159676x.2020.1831579
https://doi.org/10.1080/2159676x.2020.1831579
Autor:
Mary E. Ballestas, Sooryanarayana Varambally, Suman Karki, Richard Kirkman, Anirban Kundu, Sejong Bae, Arindam P. Ghosh, Sunil Sudarshan, Sandeep B. Shelar, Hyeyoung Nam, Garrett J. Brinkley, James A. Mobley
Publikováno v:
J Biol Chem
Ten-eleven translocation-2 (TET2) is a member of the methylcytosine dioxygenase family of enzymes and has been implicated in cancer and aging because of its role as a global epigenetic modifier. TET2 has a large N-terminal domain and a catalytic C-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d44986a95b83689e98d14e46450491
https://doi.org/10.1074/jbc.ra119.011089
https://doi.org/10.1074/jbc.ra119.011089
Publikováno v:
Therapeutic advances in urology. 14
The decision whether to undergo prostate biopsy must be carefully weighed. Nomograms have widely been utilized as risk calculators to improve the identification of prostate cancer by weighing several clinical factors. The recent inclusion of multipar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683e21afd44a5c40e58e5121b974ca90
https://pubmed.ncbi.nlm.nih.gov/35586139
https://pubmed.ncbi.nlm.nih.gov/35586139