Zobrazeno 1 - 10
of 34
pro vyhledávání: '"A. I. Nemenov"'
Autor:
Jarret AP Weinrich, Cindy D Liu, Madison E Jewell, Christopher R Andolina, Mollie X Bernstein, Jorge Benitez, Sian Rodriguez-Rosado, Joao M Braz, Mervyn Maze, Mikhail I Nemenov, Allan I Basbaum
The general consensus is that increases in neuronal activity in the anterior cingulate cortex (ACC) contribute to pain’s negative affect. Here, usingin vivoimaging of neuronal calcium dynamics in mice, we report that nitrous oxide, a general anesth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8738aa9dedfbf90bd5aa2305c957a92
https://doi.org/10.1101/2023.04.03.534475
https://doi.org/10.1101/2023.04.03.534475
Autor:
Padmamalini Baskaran, Adithya Mohandass, Noah Gustafson, Jane Bennis, Somaja Louis, Brenda Alexander, Mikhail I. Nemenov, Baskaran Thyagarajan, Louis S. Premkumar
Publikováno v:
Pain.
Painful Diabetic Peripheral Neuropathy (PDPN) is one of the major complications of diabetes. Currently, centrally acting drugs and topical analgesics are used for treating PDPN. These drugs have adverse effects, some are ineffective and treatment wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3393f005df4befdb6068cb876f562a
https://pubmed.ncbi.nlm.nih.gov/36001079
https://pubmed.ncbi.nlm.nih.gov/36001079
Publikováno v:
Current diabetes reviews. 18(5)
The cutaneous mechanisms that trigger spontaneous neuropathic pain in diabetic peripheral neuropathy (PDPN) are far from clear. Two types of nociceptors are found within the epidermal and dermal skin layers. Small-diameter lightly myelinated Aδ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b319a75df28473590d0bacf6bfba6a
https://pubmed.ncbi.nlm.nih.gov/34879806
https://pubmed.ncbi.nlm.nih.gov/34879806
Publikováno v:
Pain Medicine. 14:417-421
Sensory function of small peripheral nerve fiber was assessed by means of quantitative sensory testing (QST) during which sensory stimulation was provided using diode laser (DL) in patients suffering from painful neuropathy (PN) and compared with sym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677e77be766dbe1ec250e4002c02dbb2
https://doi.org/10.1111/pme.12049
https://doi.org/10.1111/pme.12049
Publikováno v:
The Journal of Physiology. 591:1097-1110
We previously demonstrated that genetic and/or pharmacological ablation of the TRPV1+/peptidergic or the MrgprD+/non-peptidergic subset of nociceptors produced selective, modality-specific deficits in the behavioural responses to heat and mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3a757312c6a680ec9fb81bb171a63c0
https://doi.org/10.1113/jphysiol.2012.242115
https://doi.org/10.1113/jphysiol.2012.242115
Autor:
Martin S. Angst, Alexander Tzabazis, Michael Klukinov, David C. Yeomans, Sonia Crottaz-Herbette, Michael I. Nemenov
Publikováno v:
Molecular Pain
Molecular Pain, Vol 7, Iss 1, p 18 (2011)
Molecular Pain, Vol 7, Iss 1, p 18 (2011)
Background: Two main classes of peripheral sensory neurons contribute to thermal pain sensitivity: the unmyelinated C fibers and thinly myelinated Aδ fibers. These two fiber types may differentially underlie different clinical pain states and distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982e8ee9445c0bebcd02562f558ce2b5
https://doi.org/10.1186/1744-8069-7-18
https://doi.org/10.1186/1744-8069-7-18
Autor:
Dieuwke S. Veldhuijzen, Jiachen Zhuo, Michael I. Nemenov, Joel D. Greenspan, Michael L. Keaser, Rao P. Gullapalli
Publikováno v:
Pain. 141:104-113
An important question remains as to how the brain differentially processes first (pricking) pain mediated by Adelta-nociceptors versus second (burning) pain mediated by C-nociceptors. In the present cross-over randomized, within-subjects controlled s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f94aa4d6a3d7d3e569dc7e1f6166ec7
https://doi.org/10.1016/j.pain.2008.10.027
https://doi.org/10.1016/j.pain.2008.10.027
Publikováno v:
Pain. 140:249-253
Nearly 20% of the adult population in Europe suffers from moderate to severe chronic pain and only half receive beneficial treatment [8]. In US, 37% of younger adults and 57% of older adults suffer with pain lasting at least a year [9]. Despite the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb277d7054c67372465798b760faef3
https://doi.org/10.1016/j.pain.2008.09.024
https://doi.org/10.1016/j.pain.2008.09.024
Autor:
Evan E. Lebovitz, Jason M. Keller, Michael I. Nemenov, Kendall Mitchell, Andrew J. Mannes, Michael J. Iadarola
TRPV1 is expressed in a subpopulation of myelinated Aδ and unmyelinated C-fibers. TRPV1+ fibers are essential for the transmission of nociceptive thermal stimuli and for the establishment and maintenance of inflammatory hyperalgesia. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4707c7a628831c84a5d752762e7f5876
https://europepmc.org/articles/PMC4567256/
https://europepmc.org/articles/PMC4567256/
Publikováno v:
The Journal of physiology. 591(4)
We previously demonstrated that genetic and/or pharmacological ablation of the TRPV1+/peptidergic or the MrgprD+/non-peptidergic subset of nociceptors produced selective, modality-specific deficits in the behavioural responses to heat and mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b87d6b46eda588eadea4d096e9c8e59f
https://pubmed.ncbi.nlm.nih.gov/23266932
https://pubmed.ncbi.nlm.nih.gov/23266932