Zobrazeno 1 - 10
of 75
pro vyhledávání: '"A. I. Kornelyuk"'
Autor:
L. A. Kolomiets-Babenko, O. S. Bohorad-Kobelska, N. L. Kovalchuk, M. Ja. Spivak, A. I. Kornelyuk
Publikováno v:
Biotechnologia Acta, Vol 9, Iss 5, Pp 18-23 (2016)
The goal of the research was to determine the ability of new nanocomposite preparation EMAP II (endothelial monocyte activating poplypeptide II) to affect the expression of the tumor-necrosis factor and interferon in vitro. In the experiments, the tr
Externí odkaz:
https://doaj.org/article/baaff094348e4ff991cbf2361d205dd2
Autor:
O. V. Savytskyi, A. I. Kornelyuk
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 6, Pp 142-153 (2015)
The computational structural models of human tyrosyl-tRNA synthetase and its mutant form G41R (Charcot-Marie-Tooth associated) were constructed, while their whole structural coordinates are still unknown. Grid-services of MolDynGrid Virtual Laborat
Externí odkaz:
https://doaj.org/article/7e9942cd68914b538a5475777981b6b9
Publikováno v:
Biopolymers and Cell. 39:24-32
Publikováno v:
Biopolymers and Cell. 38:9-16
Publikováno v:
Microbiology&Biotechnology. :27-39
Aim. Isolation and analysis of the structure of the mutant monotryptophan protein mini BtTyrRS for study of conformational changes of the enzyme at the stage of interaction with tRNA using fluorescence spectroscopy and determination of the effect of
Publikováno v:
Biopolymers and Cell. 36:329-340
Publikováno v:
Visnik ukrains'kogo tovaristva genetikiv i selekcioneriv. 17:196-203
Aim. The aim of our work was to optimize the scheme of obtaining primary cell culture of malignant gliomas, which can be a model for a personalized approach in the selection of chemotherapeutic exposure tactics. Methods. The standard glioma cell line
Publikováno v:
Pharmacological Reports. 72:238-245
Protein-based pharmaceuticals are among the fastest growing categories of therapeutic agents in the clinic and as commercial products, and typically target high-impact areas such as various cancers, autoimmune diseases and metabolic disorders. The ai
Publikováno v:
Cytology and Genetics. 53:219-226
Site-directed mutagenesis of the N-terminal catalytic module of Bos taurus tyrosyl-tRNA synthetase (mini-BtTyrRS) with the substitution of three Trp residues by Ala residues in its structure using the modified QuikChange method was performed to study
Predicting the Protein Tertiary Structure by Hybrid Clonal Selection Algorithms on 3D Square Lattice
Autor:
Eduard Ryzhkov, Mariia Voronenko, A. I. Kornelyuk, Volodymyr Lytvynenko, Andrey Fefelov, Anatoliy Sachenko, Iryna Fefelova
Publikováno v:
2020 IEEE 15th International Conference on Advanced Trends in Radioelectronics, Telecommunications and Computer Engineering (TCSET).
The article considers the task of predicting the tertiary structure of a protein based on its primary sequence. The task of protein folding is solved by searching for conformation with minimal energy, if you look in terms of optimization problem. The