Zobrazeno 1 - 10
of 22
pro vyhledávání: '"A. I. Kokaji"'
Autor:
Rafael D. Melani, Vincent R. Gerbasi, Lissa C. Anderson, Jacek W. Sikora, Timothy K. Toby, Josiah E. Hutton, David S. Butcher, Fernanda Negrão, Henrique S. Seckler, Kristina Srzentić, Luca Fornelli, Jeannie M. Camarillo, Richard D. LeDuc, Anthony J. Cesnik, Emma Lundberg, Joseph B. Greer, Ryan T. Fellers, Matthew T. Robey, Caroline J. DeHart, Eleonora Forte, Christopher L. Hendrickson, Susan E. Abbatiello, Paul M. Thomas, Andy I. Kokaji, Josh Levitsky, Neil L. Kelleher
Publikováno v:
Science
Human biology is tightly linked to proteins, yet most measurements do not precisely determine alternatively spliced sequences or posttranslational modifications. Here, we present the primary structures of ~30,000 unique proteoforms, nearly 10 times m
Autor:
Hitesh Arora, Sandra Babic, Tracy Lee, Trevor Rogers, Allen C. Eaves, Sharon A. Louis, Mark A. Brown, Andy I. Kokaji, Nooshin Tabatabaei-Zavareh
Publikováno v:
The Journal of Immunology. 208:172.15-172.15
Mouse B cells are used in workflows to discover novel therapeutic antibodies or develop preclinical applications using genetically engineered B cells. In vitro expansion of B cells offers the opportunity to improve the recovery of antibody sequences
Autor:
Vesna Posarac, G Neil MacDonald, Chris A. Buck, Eric Toombs, Savannah D. Gellner, Susan de Jong, Mark E. Williamson, Oliver Egeler, Bob Dalton, Andy I. Kokaji, Allen C. Eaves, Sharon A. Louis, Frann Antignano
Publikováno v:
The Journal of Immunology. 208:173.06-173.06
Large-scale cell isolation is commonly performed in labs and core facilities for cell banking and drug discovery, and as a critical step in cell therapy manufacturing. Current methods can be a significant bottleneck in a lab’s workflow, often requi
Autor:
G. Neil MacDonald, Eric Toombs, Susan de Jong, Karina L McQueen, Allen C Eaves, Sharon A. Louis, Andy I Kokaji
Publikováno v:
The Journal of Immunology. 206:26.08-26.08
Isolating cells from large volume-samples such as leukapheresis or whole blood bags is a common procedure that precedes many immunological studies. Working with large volumes can be challenging as the sample often needs to be split and processed in p
Autor:
Frann Antignano, Vesna Posarac, Catherine L Ewen, Vida K Jovanovic, Alice Liang, Steven M Woodside, Andy I Kokaji, Allen C Eaves, Terry E Thomas
Publikováno v:
The Journal of Immunology. 204:242.38-242.38
The study of immune cell function in non-lymphoid tissue and tumors promises to elucidate novel strategies to treat immune disorders, infectious diseases, and cancer. To address the challenge of isolating leukocytes from complex and variable tissues
Autor:
Grace FT Poon, Frann Antignano, Lyz Boyd, Siobhan Ennis, Joe Deng, Andy I Kokaji, Steven M Woodside, Allen C Eaves, Sharon A Louis
Publikováno v:
The Journal of Immunology. 204:242.2-242.2
Cell-based immunotherapy is being evaluated in various types of cancer and it is one of the most rapidly growing and promising areas of cancer research. Tumor-infiltrating leukocytes (TILs) consist of highly diverse leukocyte subsets with major roles
Autor:
Frann Antignano, Grace Poon, Valerie Facca, Lea Separovic, Yanet Valdez, Andy I Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 202:130.18-130.18
Immune cell function is often tissue-specific, therefore isolating cells from their tissue microenvironment is necessary to better understand their role in health and disease. This can be challenging in the presence of non-immune, tissue-derived cell
Autor:
Vesna Posarac, Catherine L. Ewen, Vida K. Jovanovic, Elisha Hayer, Andy I. Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 202:130.14-130.14
The study of immune cell function in non-lymphoid tissue and tumors has emerged as an exciting research area, with the promise to provide novel strategies for the treatment of immune disorders, infectious diseases and cancer. A major challenge in the
Autor:
Jessie Yu, Priscilla Chen, Ashley Watson, Danielle Truong, Jennifer Antonchuk, Andy I Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 202:71.3-71.3
Cancer immunotherapy using CAR T-cells is a rapidly progressing field and manufacturing these cells is a complex process that requires multiple optimization steps. We have developed reagents for the isolation, activation and expansion of human T cell
Autor:
Frann Antignano, Melina Messing, Michael R Hughes, Kelly McNagny, Andy I Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 202:58.3-58.3
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that regulate immune responses in cancer, chronic infections and inflammatory conditions. In an individual with a tumor burden, MDSCs accumulate in peripheral lymphoid o