Zobrazeno 1 - 10
of 586
pro vyhledávání: '"A. I. Gray"'
Autor:
K. H. Baker, H. W. I. Gray, A. M. Lister, N. Spassov, A. J. Welch, K. Trantalidou, B. De Cupere, E. Bonillas, M. De Jong, C. Çakırlar, N. Sykes, A. R. Hoelzel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Anthropogenic factors have impacted the diversity and evolutionary trajectory of various species. This can be through factors such as pressure on population size or range, habitat fragmentation, or extensive manipulation and translocation. H
Externí odkaz:
https://doaj.org/article/201c0971f0104a5c9701206506a3648b
Autor:
Nishant K. Singh, Jesus A. Alonso, Jason R. Devlin, Grant L. J. Keller, George I. Gray, Adarsh K. Chiranjivi, Sara G. Foote, Lauren M. Landau, Alyssa G. Arbuiso, Laura I. Weiss, Aaron M. Rosenberg, Lance M. Hellman, Michael I. Nishimura, Brian M. Baker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
MHC restriction depicts CD4+ T cell activation by MHC-II and CD8A+ by MHC-I, but rare T cells with mismatched MHC restriction have been reported. Here the authors use crystallography to describe features of such a mismatched TCR-MHC interaction and i
Externí odkaz:
https://doaj.org/article/0743243588da4db7b9427d68ad78e7b9
Autor:
Tiffany Shi, Ashley R. Burg, J. Timothy Caldwell, Krishna M. Roskin, Cyd M. Castro-Rojas, P. Chukwunalu Chukwuma, George I. Gray, Sara G. Foote, Jesus A. Alonso, Carla M. Cuda, David A. Allman, James S. Rush, Catherine H. Regnier, Grazyna Wieczorek, Rita R. Alloway, Adele R. Shields, Brian M. Baker, E. Steve Woodle, David A. Hildeman
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Bulk analysis of renal allograft biopsies (rBx) identified RNA transcripts associated with acute cellular rejection (ACR); however, these lacked cellular context critical to mechanistic understanding of how rejection occurs despite immunosuppression
Externí odkaz:
https://doaj.org/article/42e02f11da09405283e3b6ddcd572117
Autor:
Michael Chait, Mine M. Yilmaz, Shanila Shakil, Amy W. Ku, Pranay Dogra, Thomas J. Connors, Peter A. Szabo, Joshua I. Gray, Steven B. Wells, Masaru Kubota, Rei Matsumoto, Maya M.L. Poon, Mark E. Snyder, Matthew R. Baldwin, Peter A. Sims, Anjali Saqi, Donna L. Farber, Stuart P. Weisberg
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Respiratory failure in COVID-19 is characterized by widespread disruption of the lung’s alveolar gas exchange interface. To elucidate determinants of alveolar lung damage, we performed epithelial and immune cell profiling in lungs from 24 COVID-19
Externí odkaz:
https://doaj.org/article/6facbd90a1774198bb163fe2a1fbe942
Autor:
Samya S. Alenezi, Manal J. Natto, John O. Igoli, Alexander I. Gray, James Fearnley, Hugo Fearnley, Harry P. de Koning, David G. Watson
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 201-207 (2020)
A bioassay-guided phytochemical investigation of propolis samples from Tanzania and Zambia that screened for activity against Trypanosoma brucei has led to the isolation of two novel flavanones with promising antitrypanosomal activity. The compounds
Externí odkaz:
https://doaj.org/article/7fdd93600ced42479704d0c14f4e3b2a
Autor:
Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson
Publikováno v:
Molecules, Vol 28, Iss 2, p 622 (2023)
Propolis is a resin that is gathered by bees from exudates produced by various plants. Its exact chemical composition depends on the plants available near the hive. Bees use propolis to coat the surfaces of the hive, where it acts as an anti-infectiv
Externí odkaz:
https://doaj.org/article/4e50d5735c9a4b678a2025f635e82c59
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 9, Iss , Pp 54-58 (2019)
The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography. These compounds as well as the Samorin mixture and the other phenanthrid
Externí odkaz:
https://doaj.org/article/0d2e39fcb4c6402a91bba21a31244e4b
Autor:
John V. Anyam, Priscilla E. Daikwo, Marzuq A. Ungogo, Nwakaego E. Nweze, Ngozichukwuka P. Igoli, Alexander I. Gray, Harry P. De Koning, John O. Igoli
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The powdered roots of the medicinal plant Acacia nilotica were extracted with hexane and ethyl acetate, and the extracts were subjected to column chromatography for the isolation of potentially bioactive compounds and their screening against kinetopl
Externí odkaz:
https://doaj.org/article/51a6d047a8324de680e843bc78838c3e
Autor:
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was asse
Externí odkaz:
https://doaj.org/article/f24f091353d845b49a310b48bae536ce
Autor:
Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson
Publikováno v:
Molecules, Vol 27, Iss 5, p 1622 (2022)
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followe
Externí odkaz:
https://doaj.org/article/975c2535760043c686171cdcfa35f366