Zobrazeno 1 - 10 of 20 pro vyhledávání: '"A. I. Damanakis"'
1
Akademický článek
Extent and clinical significance of the therapy-relevant tight junction protein Claudin 18.2 in pancreatic ductal adenocarcinoma - real-world evidence
Autor: Su Ir Lyu, Caroline Fretter, Adrian Georg Simon, Sarah-Michele Spielmann, Alexander I. Damanakis, Yue Zhao, Christiane J. Bruns, Thomas Schmidt, Felix C. Popp, Dirk Waldschmidt, Alexander Quaas, Karl Knipper
Publikováno v: Translational Oncology, Vol 47, Iss , Pp 102044- (2024)
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is associated with poor prognosis, wherefore targeted therapies have experienced increasing interest. Zolbetuximab is a novel targeted therapy under investigation in patients with PDAC and targets Clau
Externí odkaz: https://doaj.org/article/803f8a24c6914c3d93ee38a112566f6d
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2
Akademický článek
High NANOG expression correlates with worse patients’ survival in esophageal adenocarcinoma
Autor: Karl Knipper, Alexander I. Damanakis, Su Ir Lyu, Adrian Georg Simon, Isabell Wahler, Christiane J. Bruns, Wolfgang Schröder, Thomas Schmidt, Alexander Quaas
Publikováno v: BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Patients diagnosed with esophageal cancer demonstrate a low overall survival even despite the established multimodal therapy as the current standard of care. Therefore, further biomarkers for patients with high-risk and additional
Externí odkaz: https://doaj.org/article/c2888846eb4c48eb982ddd3ec82869ca
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3
Akademický článek
Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinoma
Autor: Alexander I. Damanakis, Isabell Wahler, Hans Fuchs, Heike Löser, Wolfgang Schröder, Thomas Zander, Seung-Hun Chon, Christiane Bruns, Alexander Quaas, Florian Gebauer
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Today, individual prognosis in patients with adenocarcinoma of the esophagus (EAC) is based on post-surgical TNM staging and valid biomarkers are still not implemented. Integrin beta1 (ITGB1) is widely expressed in epithelial cells and promo
Externí odkaz: https://doaj.org/article/8a80e0a2b5c84f779a30dbf7d1d4a1cf
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4
Akademický článek
SARS-CoV-2–specific immune responses in boosted vaccine recipients with breakthrough infections during the Omicron variant surge
Autor: Bezawit A. Woldemeskel, Caroline C. Garliss, Tihitina Y. Aytenfisu, Trevor S. Johnston, Evan J. Beck, Arbor G. Dykema, Nicole Frumento, Desiree A. Wright, Andrew H. Yang, Alexander I. Damanakis, Oliver Laeyendecker, Andrea L. Cox, Heba H. Mostafa, Andrew H. Karaba, Joel N. Blankson
Publikováno v: JCI Insight, Vol 7, Iss 10 (2022)
Background Breakthrough SARS-CoV-2 infections in vaccinated individuals have been previously associated with suboptimal humoral immunity. However, less is known about breakthrough infections with the Omicron variant.Methods We analyzed SARS-CoV-2–s
Externí odkaz: https://doaj.org/article/789f009a8aaa4204841d9be38372de96
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5
Akademický článek
Proposal for a definition of 'Oligometastatic disease in pancreatic cancer'
Autor: Alexander I. Damanakis, Luisa Ostertag, Dirk Waldschmidt, Fabian Kütting, Alexander Quaas, Patrick Plum, Christiane J. Bruns, Florian Gebauer, Felix Popp
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background To date, patients with metastasized pancreatic ductal adenocarcinoma (PDAC M1) are regarded as a uniform collective. We hypothesize the existence of oligometastatic disease (OMD): a state of PDAC M1 disease with better tumor biolo
Externí odkaz: https://doaj.org/article/63ab73c666e34ca1add759076d596445
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8
X-linked inhibitor of apoptosis protein is a prognostic marker for a favorable outcome in three identified subsets in resectable adenocarcinoma of the pancreas
Autor: Karl, Knipper, Su Ir, Lyu, Heike, Goebel, Alexander I, Damanakis, Yue, Zhao, Christiane J, Bruns, Thomas, Schmidt, Hamid, Kashkar, Alexander, Quaas, Lars M, Schiffmann, Felix C, Popp
Publikováno v: Journal of cancer research and clinical oncology.
Pancreatic ductal adenocarcinoma (PDAC) is currently one of the leading causes of cancer death worldwide. Therefore, building further subgroups as well as enabling individual patient therapy and diagnostics are needed. X-linked inhibitor of apoptosis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6429a88dfc3409b621dfe4fac55a86e0
https://pubmed.ncbi.nlm.nih.gov/36472768
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9
Specific Subtypes of Carcinoma-Associated Fibroblasts Are Correlated with Worse Survival in Resectable Pancreatic Ductal Adenocarcinoma
Autor: Karl Knipper, Alexander I. Damanakis, Yue Zhao, Christiane J. Bruns, Thomas Schmidt, Felix C. Popp, Alexander Quaas, Su Ir Lyu
Publikováno v: Cancers; Volume 15; Issue 7; Pages: 2049
Purpose: The pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer entities. Effective therapy options are still lacking. The tumor microenvironment possibly bears further treatment possibilities. This study aimed to describe the e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd620b82dba5b04d340bfd7bf2929389
https://doi.org/10.3390/cancers15072049
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10
Molekulare Prädiktoren für den Krankheitsverlauf und die individualisierte Therapie beim Pankreaskarzinom
Autor: Christiane Bruns, Florian Gebauer, A. I. Damanakis
Publikováno v: Der Chirurg. 91:642-649
Das Verstandnis fur die Entstehung des Pankreaskarzinoms hat sich in den letzten zwei Jahrzehnten erheblich weiterentwickelt. Hierfur sind vor allem die Fortschritte und der Einsatz von Verfahren zur molekularbiologischen Analyse von Pankreaskarzinom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a85e8438a367b0a2c18fb87d8237087
https://doi.org/10.1007/s00104-020-01172-0
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