Quantitative Assessment of Optimal Bone Marrow Site for the Isolation of Porcine Mesenchymal Stem Cells

Autor: J. S. McDaniel, B. Antebi, M. Pilia, B. J. Hurtgen, S. Belenkiy, C. Necsoiu, L. C. Cancio, C. R. Rathbone, A. I. Batchinsky

Publikováno v: Stem Cells International, Vol 2017 (2017)

Background. One of the most plentiful sources for MSCs is the bone marrow; however, it is unknown whether MSC yield differs among different bone marrow sites. In this study, we quantified cellular yield and evaluated resident MSC population from five

Externí odkaz: https://doaj.org/article/931de9377d5241eb999a78d953832e1b

A Clinical‐Scale Microfluidic Respiratory Assist Device with 3D Branching Vascular Networks

Autor: Brett C. Isenberg, Else M. Vedula, Jose Santos, Diana J. Lewis, Teryn R. Roberts, George Harea, David Sutherland, Beau Landis, Samuel Blumenstiel, Joseph Urban, Daniel Lang, Bryan Teece, WeiXuan Lai, Rose Keating, Diana Chiang, Andriy I. Batchinsky, Jeffrey T. Borenstein

Publikováno v: Advanced Science, Vol 10, Iss 18, Pp n/a-n/a (2023)

Abstract Recent global events such as COVID‐19 pandemic amid rising rates of chronic lung diseases highlight the need for safer, simpler, and more available treatments for respiratory failure, with increasing interest in extracorporeal membrane oxy

Externí odkaz: https://doaj.org/article/9f932182866646569733d30de52de141

A Multicenter Evaluation of the Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19

Autor: Stephen A. Chitty, MD, Sarah Mobbs, FNP-BC, Brian S. Rifkin, MD, Steven W. Stogner, MD, Michael S. Lewis, MD, Jaime Betancourt, MD, Jeffrey DellaVolpe, MD, Fadi Abouzahr, MD, Andrew M. Wilhelm, DO, Harold M. Szerlip, MD, Amay Parikh, MD, Robert M. Gaeta, DO, Ian Rivera, MD, Caroline Park, MD, MPH, Benjamin Levi, MD, George L. Anesi, MD, MSCE, MBE, Karl C. Alcover, PhD, Thomas B. Arnold, BA, Jeffrey T. Howard, PhD, Kumar Sharma, MD, Kathleen P. Pratt, PhD, Ian J. Stewart, MD, Kevin K. Chung, MD, for the PURIFY Investigators, Amay Parikh, Sarah Guyler, Harold Szerlip, Giselle Carino, Tanqunisha Coleman, Robert J. Walter, Mai Nguyen, Robert Gaeta, Ian M. Rivera, Ferdinand Bacomo, Sean C. Reilly, Susan D. Rogers, Delia Marshall, Melba Francis, Sholanda Henderson, Bob Ward, Keith McCrea, Erdie de Peralta, Lakhmir S. Chawla, Andrea Worsham, Michael Benjamin, Brian Rifkin, Steven Stogner, Steve Farrell, Karen Brooks, Maria Voelkel, Sophie Haralson, Marianne Spevak, Daniell Clark, Laura Osgood, Qianru Wu, Kevin Grant, Rittal Mehta, Jeffrey Dellavolpe, Fadi Abouzahr, Mohammed Ahmed, Ginger Dowell, Stephen Amerson, Stephen Chitty, Srah Mobbs, Gwen Gratto-Cox, Christy Jordan, George Peoples, Dan Hargrove, Karen Arrington, Lauren Zahra, Jessica Raley, Katie Lyon, Rachel Macomber, Ashlee Richie, Tineka Brown, Laura Richie, Susan Hargrove, Emily Scribe, Steven White, Kevin Chung, Ian Stewart, Kathleen Pratt, Karl Alcover, Thomas B. Arnold, Lauren Walker, Amy Laczek, Breandan Sullivan, Nick Naughton, Sabrina Espinoza, Vikhyat Bebarta, Adit Ginde, Anip Bansal, Ilona Dewald, Isidro Susano Basilio, Andrew Wilhelm, Delia Owens, George L. Anesi, Kumar Sharma, Subrata Debnath, Sean P. Barnett, Nicholas S. Niazi, Jeffrey Howard, Benjamin Levi, Caroline Park, Tamim Hamdi, Peiman Lahsaei, Nilum Rajora, Christopher Choi, Andriy I Batchinsky, Michael Lewis, Jaime Betancourt, Nancy Mohler, Natalia Dudek, Jasmine Bagnas, James Oliver, Stephen Olson, Jenny Nguyen

Publikováno v: Critical Care Explorations, Vol 4, Iss 4, p e0662 (2022)

OBJECTIVES:. The Seraph100 Microbind Affinity Blood Filter (Seraph 100) (ExThera Medical, Martinez, CA) is an extracorporeal therapy that can remove pathogens from blood, including severe acute respiratory syndrome coronavirus 2. The aim of this stud

Externí odkaz: https://doaj.org/article/3f6a8767ddbf40e0969d51375bf485d0

Surface Modification of Oxygenator Fibers with a Catalytically Active Metal–Organic Framework to Generate Nitric Oxide: An Ex Vivo Pilot Study

Autor: Tracey V. Wick, Teryn R. Roberts, Andriy I. Batchinsky, Robert R. Tuttle, Melissa M. Reynolds

Publikováno v: ACS Applied Bio Materials. 6:1953-1959

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4d9c18ffd95587e9dd7a96285375b22
https://doi.org/10.1021/acsabm.3c00154

HMGB1 Inhibition to Ameliorate Organ Failure and Increase Survival in Trauma

Autor: Zhangsheng Yang, Milomir O. Simovic, Peter R. Edsall, Bin Liu, Tomas S. Cancio, Andriy I. Batchinsky, Leopoldo C. Cancio, Yansong Li

Publikováno v: Biomolecules, Vol 12, Iss 1, p 101 (2022)

Several preclinical and clinical reports have demonstrated that levels of circulating high mobility group box 1 protein (HMGB1) are increased early after trauma and are associated with systemic inflammation and clinical outcomes. However, the mechani

Externí odkaz: https://doaj.org/article/5f0ad772a78c42068db37f8286fbf818