Zobrazeno 1 - 10
of 112
pro vyhledávání: '"A. Hlobilkova"'
Autor:
Kryštof, Vladimír, Moravcová, Daniela, Paprskářová, Martina, Barbier, Pascale, Peyrot, Vincent, Hlobilková, Alice, Havlíček, Libor, Strnad, Miroslav
Publikováno v:
In European Journal of Medicinal Chemistry 2006 41(12):1405-1411
Publikováno v:
In Biochemical Pharmacology 2002 63(6):1177-1181
Autor:
Jan Bouchal, Katerina Bouchalova, Gvantsa Kharaishvili, Jana Vrbkova, Magdalena Megova, Alice Hlobilkova
Publikováno v:
ResearcherID
Background: Breast cancer (BC), the most frequent malignancy in women worldwide, is currently diagnosed in about 1.4 million female patients annually. Approximately 10-20% of BC is represented by triple negative breast cancer (TNBC) which is aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084d3453881bde2bff390f7504ae119f
https://doi.org/10.2174/1389450115666141106151143
https://doi.org/10.2174/1389450115666141106151143
Autor:
Hans Skovgaard Poulsen, Jiri Bartek, Helle Broholm, Ondrej Kalita, Petra Hamerlik, Jiri Ehrmann, Jiri Lukas, Alice Hlobilkova, Marie-Thérése Stockhausen, Laursen H, Zdenek Kolar, J Bartkova
Publikováno v:
Oncogene. 29:5095-5102
Malignant gliomas, the deadliest of brain neoplasms, show rampant genetic instability and resistance to genotoxic therapies, implicating potentially aberrant DNA damage response (DDR) in glioma pathogenesis and treatment failure. Here, we report on g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cd6dda52d3b31e5a54fab8a8563a20
https://doi.org/10.1038/onc.2010.249
https://doi.org/10.1038/onc.2010.249
Publikováno v:
Biomedical Papers. 147:11-17
The molecular basis for the transition of carcinoma of the prostate from androgen-dependent to androgen-independent growth is largely unknown. Currently for example, it is not clear whether the androgen-independent phenotype is a result of selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a042d9ce88d803052276d553f1ee90
https://doi.org/10.5507/bp.2003.002
https://doi.org/10.5507/bp.2003.002
Autor:
Marian Hajduch, Shantha Perera, Paul Murray, Miroslav Strnad, Mad'arová J, Vojtesek B, Lukesová M, Alice Hlobilkova, Zdenek Kolar, René Lenobel
Publikováno v:
Molecular Pathology. 55:227-234
Aims: Because of the high prevalence of prostatic cancer and the limitations of its treatment, enormous effort has been put into the development of new therapeutic modalities. One potential tool is the use of cyclin dependent kinase (CDK) inhibitors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a5d8a577863bf22db0aa2bb70bc51e
https://doi.org/10.1136/mp.55.4.227
https://doi.org/10.1136/mp.55.4.227
Publikováno v:
Biochemical Pharmacology. 63:1177-1181
The effects of the 17beta-estradiol, dihydrotestosterone and hormone antagonists tamoxifen and bicalutamide on telomerase activity and expression of cell cycle related proteins in the androgen-sensitive prostatic cancer cell line LNCaP were studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ab34bfa6c7a13215c7ab24439badfe
https://doi.org/10.1016/s0006-2952(01)00927-3
https://doi.org/10.1016/s0006-2952(01)00927-3
Autor:
Rudolf Nenutil, Paul Murray, B Vojtĕsek, D Cernochová, Zdenek Kolar, E Pospísilová, V Lichnovský, Alice Hlobilkova
Publikováno v:
Molecular Pathology. 51:131-137
AIMS: To study the patterns of p53 and Bcl-2 expression in relation to cell proliferation during human embryogenesis in order to help elucidate their potential roles in the regulation of cell proliferation and apoptosis during morphogenesis. METHODS:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e94a194886092f770249475119d025
https://doi.org/10.1136/mp.51.3.131
https://doi.org/10.1136/mp.51.3.131
Autor:
V. Sykorova, Daniela Kodetova, E. Vaclavikova, S. Smutny, S. Dvorakova, Jiri Hoch, Jan Laco, Jaroslav Betka, R. Kodet, Z. Novak, Jaromír Astl, B. Bendlova, A. Cibula, D. Vesely, J. Vcelak, Ales Ryska, Jan Cap, Petr Vlcek, A. Hlobilkova, Jaroslava Dušková
Publikováno v:
Journal of endocrinological investigation. 33(5)
Background: Activating point mutation of the BRAF gene, the most common genetic alteration reported in papillary thyroid carcinomas (PTC), has been associated with poor prognostic characteristics. Aim: Our objective was to determine the frequency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc31376582567618938259b4512b319
https://pubmed.ncbi.nlm.nih.gov/20009493
https://pubmed.ncbi.nlm.nih.gov/20009493
Publikováno v:
Neoplasma. 56(4)
Astrocytomas, particularly high grade astrocytoma, are brain tumors with potent angiogenic activity. Our immnunohistochemical study assessed vascular endothelial growth factor (VEGF), VEGF receptors (Flk-1, and Flt-1), the intermediate filamental pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4712e5620aba4c1945450689a1f5308b
https://pubmed.ncbi.nlm.nih.gov/19473053
https://pubmed.ncbi.nlm.nih.gov/19473053