Zobrazeno 1 - 10
of 437
pro vyhledávání: '"A. Henkensiefken"'
Autor:
Fiore Cattaruzza, Ayesha Nazeer, Milton To, Mikhail Hammond, Caitlin Koski, Lucas Y. Liu, V. Pete Yeung, Deena A. Rennerfeldt, Angela Henkensiefken, Michael Fox, Sharon Lam, Kari M. Morrissey, Zachary Lange, Vladimir N. Podust, Mika K. Derynck, Bryan A. Irving, Volker Schellenberger
Publikováno v:
Nature Cancer. 4:485-501
To enhance the therapeutic index of T-cell engagers (TCEs), we engineered masked, precision-activated TCEs (XPAT proteins), targeting a tumor antigen (human epidermal growth factor receptor 2 (HER2) or epidermal growth factor receptor (EGFR)) and CD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d08fc750f9f56209e1642cb13b83c12b
https://doi.org/10.1038/s43018-023-00536-9
https://doi.org/10.1038/s43018-023-00536-9
Autor:
Fiore Cattaruzza, Ayesha Nazeer, Zachary Lange, Caitlin Koski, Mikhail Hammond, Trang Dao-Pick, Angela Henkensiefken, Mika Derynck, Volker Schellenberger, Bryan Irving
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/251cfc5cf7644032b9a3fd31021d0f8c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Fiore Cattaruzza, Ayesha Nazeer, Milton To, Mikhail Hammond, Caitlin Koski, Lucas Liu, V. Pete Yeung, Deena Rennerfeldt, Angela Henkensiefken, Michael Fox, Sharon Lam, Kari Morrissey, Zachary Lange, Vladimir Podust, Mika Derynck, Bryan Irving, Volker Schellenberger
To enhance the therapeutic index of T-cell engagers (TCE), we engineered masked, conditionally active TCEs (XPAT proteins), targeting a tumor antigen (human epidermal growth factor receptor 2 [HER2] or epidermal growth factor receptor 2 [EGFR]) and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fbef64ebfb9ce12787efd733daeaf5
https://doi.org/10.21203/rs.3.rs-2045998/v1
https://doi.org/10.21203/rs.3.rs-2045998/v1
Autor:
Kumar, Aditya, Oey, Tandre, Falla, Guillermo Puerta, Henkensiefken, Ryan, Neithalath, Narayanan, Sant, Gaurav
Publikováno v:
In Construction and Building Materials June 2013 43:428-435
Publikováno v:
Strain. Jun2011 Supplement, Vol. 47, pe432-e441. 10p. 2 Black and White Photographs, 2 Diagrams, 8 Graphs.
Publikováno v:
In Cement and Concrete Composites 2009 31(7):427-437
Publikováno v:
In Cement and Concrete Research 2009 39(10):883-892
Autor:
Mikhail Hammond, Ayesha Nazeer, Trang Dao-Pick, Mika K. Derynck, Caitlin Koski, Zachary Lange, Volker Schellenberger, Fiore Cattaruzza, Angela Henkensiefken, Bryan Irving
Publikováno v:
Cancer Research. 81:PS17-11
Background TCEs are effective at inducing remissions in hematologic cancers but have been challenging in solid tumors due to on-target, off-tumor toxicity. Attempts to circumvent CRS include fractionated or step-up dosing and/or complex molecular des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d7d683bff007e98c6fc5c0e2555bad
https://doi.org/10.1158/1538-7445.sabcs20-ps17-11
https://doi.org/10.1158/1538-7445.sabcs20-ps17-11
Autor:
Ayesha Nazeer, Fiore Cattaruzza, Zachary Lange, Angela Henkensiefken, Bryan Irving, Mika K. Derynck, Mikhail Hammond, Volker Schellenberger, Caitlin Koski
Publikováno v:
Cancer Research. 80:3376-3376
Background: TCEs have proven to be effective in creating durable remissions in hematologic malignancies but have been challenging in solid tumors due to on-target, off-tumor toxicity. To circumvent the toxicity, many have tried step-up, fractionated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d77c267077cbde98e9c5b85a3400c80
https://doi.org/10.1158/1538-7445.am2020-3376
https://doi.org/10.1158/1538-7445.am2020-3376