Zobrazeno 1 - 10
of 9 447
pro vyhledávání: '"A. Hemminki"'
Autor:
Elise Jirovec, Dafne C. A. Quixabeira, James H. A. Clubb, Santeri A. Pakola, Tatiana Kudling, Victor Arias, Lyna Haybout, Katriina Jalkanen, Tuomo Alanko, Tine Monberg, Amir Khammari, Brigitte Dreno, Inge Marie Svane, Matthew S. Block, Daniel A. Adamo, Johanna Mäenpää, Claudia Kistler, Suvi Sorsa, Otto Hemminki, Anna Kanerva, João M. Santos, Victor Cervera-Carrascon, Akseli Hemminki
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background A limitation of approved oncolytic viruses is their requirement for intratumoral (i.t.) injection. TILT-123 (igrelimogene litadenorepvec, Ad5/3-E2F-D24-hTNFα-IRES-hIL-2) is a chimeric oncolytic adenovirus suitable for intravenous
Externí odkaz:
https://doaj.org/article/45e8bf709efc4b58a91d86132c2c2011
Autor:
Kari Hemminki, Lambertus A. Kiemeney, Alicia K. Morgans, Antti Ranniko, Renate Pichler, Otto Hemminki, Zoran Culig, Peter Mulders, Chris H. Bangma
Publikováno v:
European Urology Open Science, Vol 69, Iss , Pp 13-20 (2024)
Early recognition of hereditary urological cancers may influence diagnostic and therapeutic decision-making, and potentially alter the fate of patients and family members. Here, we introduce readers to the current knowledge on germline genetic testin
Externí odkaz:
https://doaj.org/article/6710ae1d20a44f97973f28357aa2cd86
Publikováno v:
Clinical Epidemiology, Vol Volume 16, Pp 659-671 (2024)
Frantisek Zitricky,1 Anni Koskinen,2,3 Kristina Sundquist,4– 6 Jan Sundquist,4– 6 Vaclav Liska,1,7 Asta Försti,8,9 Akseli Hemminki,10,11 Kari Hemminki1,4,12 1Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech Republic; 2De
Externí odkaz:
https://doaj.org/article/f9a601b342ae4ece85f5f95475eccb2e
Autor:
Venkata Ramana Mallela, Phanindra Babu Kasi, Dattatrya Shetti, Andriy Trailin, Lenka Cervenkova, Richard Palek, Ondřej Daum, Vaclav Liska, Kari Hemminki, Filip Ambrozkiewicz
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 4, Pp 1133-1139 (2024)
Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is poorly understood. Based on th
Externí odkaz:
https://doaj.org/article/612919be773746b0a0fc2382883ede1d
Autor:
V. Cervera-Carrascon, M. Siurala, J. M. Santos, R. Havunen, S. Tähtinen, P. Karell, S. Sorsa, A. Kanerva, A. Hemminki
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Releasing the patient's immune system against their own malignancy by the use of checkpoint inhibitors is delivering promising results. However, only a subset of patients currently benefit from them. One major limitation of these therapies relates to
Externí odkaz:
https://doaj.org/article/d89957be564a46b29a243aac324e3904
Autor:
Qiulin Huang, Youli Chen, Liyou Lian, Qiqi Lei, Jinfei Chen, Licun Wu, Kari Hemminki, Jianguang Ji, Tianhui Chen
Publikováno v:
Journal of the National Cancer Center, Vol 4, Iss 3, Pp 214-222 (2024)
Objective: To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China. Methods: Data on patients diagnosed with MM from China during 1990–2019 were obtained from the Global Burden of D
Externí odkaz:
https://doaj.org/article/056efd70ce524bfd93ea40ad71b94aa0
Autor:
Hauke Thomsen, Subhayan Chattopadhyay, Niels Weinhold, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Florentin Späth, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor condition for multiple
Externí odkaz:
https://doaj.org/article/56d5d5cebeba496e871fe8346df21e90
Autor:
Molly Went, Laura Duran-Lozano, Gisli H. Halldorsson, Andrea Gunnell, Nerea Ugidos-Damboriena, Philip Law, Ludvig Ekdahl, Amit Sud, Gudmar Thorleifsson, Malte Thodberg, Thorunn Olafsdottir, Antton Lamarca-Arrizabalaga, Caterina Cafaro, Abhishek Niroula, Ram Ajore, Aitzkoa Lopez de Lapuente Portilla, Zain Ali, Maroulio Pertesi, Hartmut Goldschmidt, Lilja Stefansdottir, Sigurdur Y. Kristinsson, Simon N. Stacey, Thorvardur J. Love, Saemundur Rognvaldsson, Roman Hajek, Pavel Vodicka, Ulrika Pettersson-Kymmer, Florentin Späth, Carolina Schinke, Frits Van Rhee, Patrick Sulem, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Ulf-Henrik Mellqvist, Ingileif Jonsdottir, Gareth Morgan, Pieter Sonneveld, Anders Waage, Niels Weinhold, Hauke Thomsen, Asta Försti, Markus Hansson, Annette Juul-Vangsted, Unnur Thorsteinsdottir, Kari Hemminki, Martin Kaiser, Thorunn Rafnar, Kari Stefansson, Richard Houlston, Björn Nilsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 case
Externí odkaz:
https://doaj.org/article/45458eb3feec4e09b1c186e45ec468d5
Autor:
Hemminki, Kari1,2 (AUTHOR) frantisel.zitricky@lfp.cuni.cz, Zitricky, Frantisek1 (AUTHOR), Försti, Asta3,4 (AUTHOR) a.foersti@dkfz.de, Tapaninen, Tuija5,6,7,8 (AUTHOR), Hemminki, Akseli9,10 (AUTHOR) akseli.hemminki@helsinki.fi, Juliusson, Gunnar11 (AUTHOR) gunnar.juliusson@med.lu.se, Niemann, Carsten Utoft12 (AUTHOR) carsten.utoft.niemann@regionh.dk
Publikováno v:
Cancers. Sep2024, Vol. 16 Issue 18, p3229. 12p.
Autor:
Hemminki, Kari1,2 (AUTHOR) k.hemminki@dkfz.de, Zitricky, Frantisek1 (AUTHOR), Försti, Asta3,4 (AUTHOR), Hemminki, Otto5,6 (AUTHOR), Liska, Vaclav1,7 (AUTHOR), Hemminki, Akseli6,8 (AUTHOR)
Publikováno v:
Cancer Medicine. Aug2024, Vol. 13 Issue 15, p1-11. 11p.