Zobrazeno 1 - 7
of 7
pro vyhledávání: '"A. Hazel Dilmore"'
Autor:
Cameron Martino, Daniel McDonald, Kalen Cantrell, Amanda Hazel Dilmore, Yoshiki Vázquez-Baeza, Liat Shenhav, Justin P. Shaffer, Gibraan Rahman, George Armstrong, Celeste Allaband, Se Jin Song, Rob Knight
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT Microbiome data have several specific characteristics (sparsity and compositionality) that introduce challenges in data analysis. The integration of prior information regarding the data structure, such as phylogenetic structure and repeated-
Externí odkaz:
https://doaj.org/article/2d05639093884dc387b8bbe22d87751e
Autor:
Cameron Martino, Amanda Hazel Dilmore, Colette Blach, Kelly Weldon, Jasmine Zemlin, Gibraan Rahman, Morgan Panitchpakdi, Kiana West
STRUCTURED ABSTRACTINTRODUCTIONThe ketogenic diet (KD) is an intriguing candidate for neuroprotection in Alzheimer’s disease (AD) given its protective effects against metabolic dysregulation and seizures. The diet’s neuroprotective effects have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633b8762b7202ae7413b9286ba27110b
https://doi.org/10.1101/2022.08.30.22279087
https://doi.org/10.1101/2022.08.30.22279087
Autor:
Faith, Dickerson, Amanda Hazel, Dilmore, Filipa, Godoy-Vitorino, Tanya T, Nguyen, Martin, Paulus, Adrian A, Pinto-Tomas, Cristofer, Moya-Roman, Ibrahim, Zuniga-Chaves, Emily G, Severance, Dilip V, Jeste
Publikováno v:
Current topics in behavioral neurosciences.
The combined genetic material of the microorganisms in the human body, known as the microbiome, is being increasingly recognized as a major determinant of human health and disease. Although located predominantly on mucosal surfaces, these microorgani
Autor:
Cameron Martino, Amanda Hazel Dilmore, Zachary M. Burcham, Jessica L. Metcalf, Dilip Jeste, Rob Knight
Publikováno v:
Nature reviews. Microbiology. 20(12)
Associations between age and the human microbiota are robust and reproducible. The microbial composition at several body sites can predict human chronological age relatively accurately. Although it is largely unknown why specific microorganisms are m
Scalable power analysis and effect size exploration of microbiome community differences with Evident
Autor:
Gibraan Rahman, Daniel McDonald, Antonio Gonzalez, Yoshiki Vázquez-Baeza, Lingjing Jiang, Climent Casals-Pascual, Shyamal Peddada, Daniel Hakim, Amanda Hazel Dilmore, Brent Nowinski, Rob Knight
Differentiating microbial communities among samples is a major objective in biomedicine. Quantifying the effect size of these differences allows researchers to understand the factors most associated with communities and to optimize the design and cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4865a49b22ef1bb4809c654117cb3ba
https://doi.org/10.1101/2022.05.19.492684
https://doi.org/10.1101/2022.05.19.492684
Autor:
Faith Dickerson, Amanda Hazel Dilmore, Filipa Godoy-Vitorino, Tanya T. Nguyen, Martin Paulus, Adrian A. Pinto-Tomas, Cristofer Moya-Roman, Ibrahim Zuniga-Chaves, Emily G. Severance, Dilip V. Jeste
Publikováno v:
Microorganisms and Mental Health ISBN: 9783031243325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d65a9f46b24d6438ab34f74849b34f
https://doi.org/10.1007/7854_2022_384
https://doi.org/10.1007/7854_2022_384
Autor:
Marcus C. S. Lee, Edward Owen, James M. Murithi, Kerry McGowen, Beatriz Baragaña, Madeline R. Luth, Emma F. Carpenter, Jacquin C. Niles, Chris Walpole, Manu Vanaerschot, Rebecca E. K. Mandt, Sabine Ottilie, Ian H. Gilbert, Avinash S. Punekar, Charisse Flerida A. Pasaje, Krittikorn Kümpornsin, Aslı Akidil, João Pedro Pisco, Kelly Rubiano, Nimisha Mittal, David A. Fidock, Robert L. Summers, De Lin, Andy Plater, Sharon M. Shepherd, Elizabeth A. Winzeler, A. Hazel Dilmore, Andrew M. Shepherd, Amanda K. Lukens, Dyann F. Wirth, Madalyn Won, Josefine Striepen, Justin Munro, Manuel Llinás
Publikováno v:
Cell Chemical Biology. 29:191-201.e8
Summary We identify the Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS) as a druggable target, using genetic and chemical validation. In vitro evolution of resistance with two antiplasmodial drug-like compounds (MMV019721 and MMV084978) s