Zobrazeno 1 - 10
of 837
pro vyhledávání: '"A. H. Low"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The bacterial tight adherence pilus system (TadPS) assembles surface pili essential for adhesion and colonisation in many human pathogens. Pilus dynamics are powered by the ATPase CpaF (TadA), which drives extension and retraction cycles in
Externí odkaz:
https://doaj.org/article/40a21052391d48629e85566a09c911da
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The bacterial Tight adherence Secretion System (TadSS) assembles surface pili that drive cell adherence, biofilm formation and bacterial predation. The structure and mechanism of the TadSS is mostly unknown. This includes characterisation of
Externí odkaz:
https://doaj.org/article/9bc2645b939c4617ac8a18162866e2ee
Autor:
Richard J Samworth, Rita Horvath, sukhdev Singh, Imogen Milner, Jenny Yang, Emma Hitchcock, Daniel MaGee, William Thompson, Emma Slack, Wentin Chen, Alexandra Thomas, Tomas Ferreira, Anson Wong, Kavyesh Vivek, Ellena Leigh, Riya Patel, Guilherme Movio, Tushar Rakhecha, Alexander M Collins, Oliver Feng, Mario K Teo, Crispin C Wigfield, Dania Al-Hashimi, Maeve K Mulchrone, Alisha Pervaiz, Heather A Lewis, Florence Gilks, Charlotte Casteleyn, Sara Kidher, Erin Fitzsimons-West, Tanzil Rujeedawa, Meghna Sreekumar, Eliza Wade, Juel Choppy-Madeleine, Yasemin Durmus, Olivia King, Yu Ning Ooi, Malvi Shah, Tan Jih Yih, Samantha Burley, Basma R Khan, Rishik S Pilla, Vaishvi Dalal, Brennan L Gibson, Emma Westwood, Brandon S H Low, Sara R Sabur, Maryam A Malik, Safa Razzaq, Amardeep Sidki, Giulia Cianci, Felicity Greenfield, Sajad Hussain, Annie Harrison, Hugo Bernie, Luke Dcaccia, Linnuel J Pregil, Olivia Rowe, Ananya Jain, Gregory K Anyaegbunam, Syed Z Jafri, Arthur Handscomb, Sudhanvita Arun, Alfaiya Hashmi, Ankith Pandian, Joseph R Nicholson, Hannah Layton-Joyce, Kouther Mohsin, Matilda Gardener, Eunice C Y Kwan, Emily R Finbow, Sakshi Roy, Zoe M Constantinou, Mackenzie Garlick, Clare L Carney, Samantha Gold, Bilal Qureshi, Grace Annetts, Tamara Magallon-McGeorge, Khyatee Shah, Kholood T Munir, Timothy Neill, Gurpreet K Atwal, Anesu Kusosa, Anthony Vijayanathan, Mia Mäntylä, Momina Iqbal, Sara Raja, Muhammad H Shah, Pranjil Pokharel, Ashna Anil, Kate Stenning, Katie Appleton, Keerthana Uthayakumar, Rajan Panacer, Yasmin Owadally, Dilaxiha Rajendran, Harsh S Modalavalasa, Marta M Komosa, Morea Turjaka, Sruthi Saravanan, Amelia Dickson, Jack M Read, Georgina Cooper, Wing Chi Do, Chiamaka Anthony-Okeke, Daria M Bageac, David C W Loh, Rida Khan, Ruth Omenyo, Aidan Baker, Manon Everard, Wajiha Rahman, Denis Chen, Michael E Bryan, Shama Maliha, Amber Dhoot Vera Onongaya, Catherine L Otoibhi, Harry Donkin-Everton, Mia K Whelan, Claudia S F Hobson, Anthony Haynes, Joshua Bayes-Green, Mariam S Malik, Subanki Srisakthivel, Sophie Kidd, Alan Saji, Govind Dhillon, Muhammed Asif, Jessica L Marshall, Nain T Raja, Tawfique Rizwan, Aleksandra Dunin-Borkowska, James Brawn, Karthig Thillaivasan, Zainah Sindhoo, Ayeza Akhtar, Kelly Fletcher, Lok Pong Cheng, Medha Pillaai, Sakshi Garg, Wajahat Khan, Ria Bhatt Ben Sweeney, Madison Slight, Adan MI Chew, Cameron Thurlow, Kriti Yadav, Niranjan Rajesh, Nathan-Dhruv Mistry, Alyssa Weissman, Juan FE Jaramillo, Gregor W Abercromby, Emily Gaskin, Chloe Milton, Matthew Kokkat, Momina Hussain, Nana A Ohene-Darkoh, Syeda T Islam, Anushruti Yadav, Eve Richings, Samuel Foxcroft, Vivek Sivadev, Harriet Charlton, James A Cairn, Julia Shaaban, Leah Njenje, Mark J Bishop, Humairaa Ismail, Sarah L Henderson, Daniel C Chalk, Daniel J Mckenna, Fizah Hasan, Kanishka Saxena, Iona E Gibson, Saad Dosani
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Objective To determine current UK medical students’ career intentions after graduation and on completing the Foundation Programme (FP), and to ascertain the motivations behind these intentions.Design Cross-sectional, mixed-methods survey of UK medi
Externí odkaz:
https://doaj.org/article/1cce37afdec140a3ba2bb154b1f5b1f6
Publikováno v:
IEEE Open Journal of Control Systems, Vol 2, Pp 49-62 (2023)
Machine-learned black-box policies are ubiquitous for nonlinear control problems. Meanwhile, crude model information is often available for these problems from, e.g., linear approximations of nonlinear dynamics. We study the problem of certifying a b
Externí odkaz:
https://doaj.org/article/01e6d739981d41ffa4e0db739e9485e9
Publikováno v:
Journal of Primary Care & Community Health, Vol 14 (2023)
Access to healthcare is a Social Determinant of Health that is associated with public health outcomes and barriers to access disproportionately affect African American adults. This study used a health and financial literacy approach to qualitatively
Externí odkaz:
https://doaj.org/article/30258ea01cf643e68918d26a713d7423
Publikováno v:
European Psychiatry, Vol 65, Pp S632-S632 (2022)
Introduction Mental illness is the single largest cause of disability in the UK, with one in four individuals suffering from a mental health problem. Despite this, only 13% of the NHS budget goes towards treatment of mental illness. It is thus unsurp
Externí odkaz:
https://doaj.org/article/c24c479896604b03ab8a43d43d7f8e35
Autor:
Carlos K. H. Wong, David T. W. Lui, Angel Y. C. Lui, Marshall C. H. Low, Ashley C. Y. Kwok, Kristy T. K. Lau, Ivan C. H. Au, Xi Xiong, Matthew S. H. Chung, Eric H. Y. Lau, Benjamin J. Cowling
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
AimThis study was conducted in order to evaluate the association between metformin use and clinical outcomes in type 2 diabetes mellitus (T2DM) patients hospitalized with coronavirus disease 2019 (COVID-19).MethodsPatients with T2DM with confirmed di
Externí odkaz:
https://doaj.org/article/c343da642d7d4e4990934d3b01d02494
Publikováno v:
IEEE Access, Vol 8, Pp 132320-132329 (2020)
We consider joint demand response and power procurement to optimize the average social welfare of a smart power grid system with renewable sources. The renewable sources such as wind and solar energy are intermittent and fluctuate rapidly. As a conse
Externí odkaz:
https://doaj.org/article/2802e2d4b74c49e4a460b87309e93d9a
Autor:
Anastasia A. Chernyatina, Harry H. Low
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Bacterial type II secretion systems (T2SSs) translocate virulence factors, toxins and enzymes across the cell outer membrane. Here, Chernyatina and Low use negative stain and cryo-electron microscopy to reveal the core architecture of an assembled T2
Externí odkaz:
https://doaj.org/article/1de41cbd5ffc46d4b3ef225bf6deedd9
Autor:
Danielle E. Anderson, Chee Wah Tan, Wan Ni Chia, Barnaby E. Young, Martin Linster, JennyG. H. Low, Yee-Joo Tan, Mark I.-C. Chen, Gavin J. D. Smith, Yee Sin Leo, David C. Lye, Lin-Fa Wang
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 900-902 (2020)
ABSTRACTDespite initial findings indicating that SARS-CoV and SARS-CoV-2 are genetically related belonging to the same virus species and that the two viruses used the same entry receptor, angiotensin-converting enzyme 2 (ACE2), our data demonstrated
Externí odkaz:
https://doaj.org/article/00cfe039fd8646cf8bc24dc32ec53072