Zobrazeno 1 - 10
of 226
pro vyhledávání: '"A. H. Handyside"'
Autor:
Rajiv C. McCoy, Michael C. Summers, Abeo McCollin, Christian S. Ottolini, Kamal Ahuja, Alan H. Handyside
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and stillbirth following natural conception as well as
Externí odkaz:
https://doaj.org/article/fb7c078a3ac84d82abec5bc3e79f16cd
Autor:
Desmond A. R. Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H. Handyside, Remi Labrecque, Marc-André Sirard, Richard D. Emes, Darren K. Griffin, Kevin D. Sinclair
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundIn vitro maturation (IVM) of germinal vesicle intact oocytes prior to in vitro fertilization (IVF) is practiced widely in animals. In human assisted reproduction it is generally reserved for fertility preservation or where ovarian stimulati
Externí odkaz:
https://doaj.org/article/af282c29578c47c285ffd4ead6fbbbbe
Autor:
Reina Jochems, Carla Canedo-Ribeiro, Giuseppe Silvestri, Martijn F. L. Derks, Hanne Hamland, Louisa J. Zak, Egbert F. Knol, Alan H. Handyside, Eli Grindflek, Darren K. Griffin
Publikováno v:
Cells, Vol 12, Iss 5, p 790 (2023)
Preimplantation genetic testing for aneuploidy (PGT-A) is widespread, but controversial, in humans and improves pregnancy and live birth rates in cattle. In pigs, it presents a possible solution to improve in vitro embryo production (IVP), however, t
Externí odkaz:
https://doaj.org/article/ca5b2eb7f5d74dc3a29518aa0593b802
Autor:
Giuseppe Silvestri, Carla Canedo-Ribeiro, María Serrano-Albal, Remi Labrecque, Patrick Blondin, Steven G. Larmer, Gabriele Marras, Desmond A.R. Tutt, Alan H. Handyside, Marta Farré, Kevin D. Sinclair, Darren K. Griffin
Publikováno v:
Cells, Vol 10, Iss 9, p 2284 (2021)
Approximately one million in vitro produced (IVP) cattle embryos are transferred worldwide each year as a way to improve the rates of genetic gain. The most advanced programmes also apply genomic selection at the embryonic stage by SNP genotyping and
Externí odkaz:
https://doaj.org/article/16ce8798766445eba54aa2f92a91d59f
Autor:
Rajiv C. McCoy, Michael C. Summers, Abeo McCollin, Christian S. Ottolini, Kamal Ahuja, Alan H. Handyside
The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and still birth following natural conception as well asin vitrofertilizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4c80f2200b0629bd16cd3a43fd33b24
https://doi.org/10.1101/2022.07.03.498614
https://doi.org/10.1101/2022.07.03.498614
Autor:
Giuseppe Silvestri, R.J. Simmons, G. Guven-Ates, Carla Canedo-Ribeiro, Rémi Labrecque, Alan H. Handyside, Patrick Blondin, Darren K. Griffin, Wing Yee Kwong, Kevin D. Sinclair, Desmond A. R. Tutt, María Serrano-Albal
Publikováno v:
Theriogenology
Contemporary systems for oocyte retrieval and culture of both cattle and human embryos are suboptimal with respect to pregnancy outcomes following transfer. In humans, chromosome abnormalities are the leading cause of early pregnancy loss in assisted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6831d98097dbefcb34c080936e5a38fd
https://doi.org/10.1016/j.theriogenology.2020.11.021
https://doi.org/10.1016/j.theriogenology.2020.11.021
Publikováno v:
Prenatal Diagnosis. 41:525-535
Preimplantation genetic testing for aneuploidy (PGT-A) by copy number analysis is now widely used to select euploid embryos for transfer. Whole or partial chromosome aneuploidy can arise in meiosis, predominantly female meiosis, or in the postzygotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375c0c02a73e6bdfd0d80589e0b4cf0
https://doi.org/10.1002/pd.5816
https://doi.org/10.1002/pd.5816
Autor:
Alan H. Handyside, Carmen Rubio, Filippo Maria Ubaldi, Laura Rienzi, Federica Innocenti, Antonio Capalbo, Danilo Cimadomo, Carmen M. García-Pascual
Publikováno v:
Human Reproduction Update. 26:453-473
Following early studies showing no adverse effects, cleavage stage biopsy by zona drilling using acid Tyrode’s solution, and removal of single blastomeres for preimplantation genetic testing (PGT) and identification of sex in couples at risk of X-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3a7911bb108b12dd6ffa69a4e1287f
https://doi.org/10.1093/humupd/dmaa019
https://doi.org/10.1093/humupd/dmaa019
Autor:
Desmond A. R. Tutt, Darren K. Griffin, Steven G. Larmer, Marta Farré, María Serrano-Albal, Carla Canedo-Ribeiro, Rémi Labrecque, Kevin D. Sinclair, Giuseppe Silvestri, Alan H. Handyside, Patrick Blondin, Gabriele Marras
Publikováno v:
Cells
Volume 10
Issue 9
Cells, Vol 10, Iss 2284, p 2284 (2021)
Volume 10
Issue 9
Cells, Vol 10, Iss 2284, p 2284 (2021)
Approximately one million in vitro produced (IVP) cattle embryos are transferred worldwide each year as a way to improve the rates of genetic gain. The most advanced programmes also apply genomic selection at the embryonic stage by SNP genotyping and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b008edd86f9f9bf57c06f42e06957e5
https://pubmed.ncbi.nlm.nih.gov/34571932
https://pubmed.ncbi.nlm.nih.gov/34571932
Autor:
Alan H. Handyside
Publikováno v:
Reproduction. 160:E1-E3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d55552d9887ff56b15510daa302872
https://doi.org/10.1530/rep-20-0412
https://doi.org/10.1530/rep-20-0412