Zobrazeno 1 - 10
of 408
pro vyhledávání: '"A. H. Goldstone"'
Autor:
Philipp Berning, Mathilde Fekom, Maud Ngoya, Anthony H. Goldstone, Peter Dreger, Silvia Montoto, Hervé Finel, Evgenii Shumilov, Patrice Chevallier, Didier Blaise, Tim Strüssmann, Ben Carpenter, Edouard Forcade, Cristina Castilla-Llorente, Marek Trneny, Hervé Ghesquieres, Saveria Capria, Catherine Thieblemont, Igor Wolfgang Blau, Ellen Meijer, Annoek E. C. Broers, Anne Huynh, Denis Caillot, Wolf Rösler, Stephanie Nguyen Quoc, Jörg Bittenbring, Arnon Nagler, Jacques-Emmanuel Galimard, Bertram Glass, Anna Sureda, Norbert Schmitz
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Autologous(auto-) and allogeneic(allo-) hematopoietic stem cell transplantation (HSCT) are key treatments for relapsed/refractory diffuse large B-cell lymphoma (DLBCL), although their roles are challenged by CAR-T-cells and other immunothera
Externí odkaz:
https://doaj.org/article/684518341f4d46cc80e9dbb9c2b0775a
Autor:
David I Marks, Amy A Kirkwood, Clare J Rowntree, Melanie Aguiar, Katharine E Bailey, Brendan Beaton, Paul Cahalin, Anna Z Castleton, Laura Clifton-Hadley, Mhairi Copland, Anthony H Goldstone, Richard Kelly, Emma Lawrie, SooWah Lee, Andrew K McMillan, Mary Frances McMullin, Tobias F Menne, Rachel J Mitchell, Anthony V Moorman, Bela Patel, Pip Patrick, Paul Smith, David Taussig, Deborah Yallop, Krisztina Zuborne Alapi, Adele K Fielding
Publikováno v:
Marks, D I, Kirkwood, A A, Rowntree, C J, Aguiar, M, Bailey, K E, Beaton, B, Cahalin, P, Castleton, A Z, Clifton-Hadley, L, Copland, M, Goldstone, A H, Kelly, R, Lawrie, E, Lee, S, McMillan, A K, McMullin, M F, Menne, T F, Mitchell, R J, Moorman, A V, Patel, B, Patrick, P, Smith, P, Taussig, D, Yallop, D, Alapi, K Z & Fielding, A K 2022, ' Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial ', The Lancet Haematology, vol. 9, no. 4, pp. e262-e275 . https://doi.org/10.1016/S2352-3026(22)00038-2
BACKGROUND: Treatment for adults with acute lymphoblastic leukaemia requires improvement. UKALL14 was a UK National Cancer Research Institute Adult ALL group study that aimed to determine the benefit of adding the anti-CD20 monoclonal antibody, ritux
Autor:
Selina M. Luger, Richard C. Harvey, Anthony H. Goldstone, Jan Barinka, Mark R. Litzow, Victoria Wang, Charles G. Mullighan, Ross L. Levine, Jacob M. Rowe, Bela Patel, Peter H. Wiernik, Zhaohui Gu, Adele K. Fielding, Kathryn G. Roberts, Zhongshan Cheng, David I. Marks, Ari Melnick, Georgina Buck, Elisabeth Paietta, Yanming Zhang, Omar Abdel-Wahab, Deqing Pei, Janis Racevskis, Gordon W. Dewald, Hillard M. Lazarus, Anthony V. Moorman, Cheng Cheng, Rhett P. Ketterling, Letizia Foroni, Stanley Pounds, Cheryl L. Willman, David Alejos, Lei Shi, Gang Wu, Chunxu Qu, Martin S. Tallman
Publikováno v:
Blood
Genomic classification has improved risk assignment of pediatric, but not adult B-lineage acute lymphoblastic leukemia (B-ALL). The international UKALLXII/ECOG-ACRIN E2993 (#NCT00002514) trial accrued 1229 adolescent/adult patients with BCR-ABL1− B
Autor:
Ruth Pettengell, Ariane Boumendil, Joanna Romejko-Jarosinska, R Johnson, Peter Dreger, Stephen P. Robinson, Alejandro Martín, Eva Kimby, N. Schmitz, P Giri, Carsten Utoft Niemann, Anthony H. Goldstone, Isabelle Bence-Bruckler, Bernd Metzner, Silvia Montoto, Ruzena Uddin
Publikováno v:
Bone Marrow Transplantation. 56:1413-1421
We report the 12-year follow-up of the prospective randomized EBMT LYM1 trial to determine whether the benefit of brief duration rituximab maintenance (RM) on progression-free survival (PFS) in patients with relapsed follicular lymphoma (FL) receivin
Autor:
Paul Ferguson, Robert K. Hills, Angela Grech, Sophie Betteridge, Lars Kjeldsen, Michael Dennis, Paresh Vyas, Anthony H. Goldstone, Donald Milligan, Richard E. Clark, Nigel H. Russell, Charles Craddock
Publikováno v:
Haematologica, Vol 101, Iss 11 (2016)
Up to 30% of adults with acute myeloid leukemia fail to achieve a complete remission after induction chemotherapy - termed primary refractory acute myeloid leukemia. There is no universally agreed definition of primary refractory disease, nor have th
Externí odkaz:
https://doaj.org/article/f772d011430040108f48560b445e89d7
Autor:
Martin S. Tallman, Susan M. Richards, Xin V. Wang, David I. Marks, Anthony H. Goldstone, Charles G. Mullighan, Jacob M. Rowe, Mark R. Litzow, Georgina Buck, Peter H. Wiernik, Kathryn G. Roberts, Letizia Foroni, Cheryl L. Willman, Dan Douer, Chezi Ganzel, Hillard M. Lazarus, Elisabeth Paietta, Selina M. Luger
Publikováno v:
British Journal of Haematology
Summary Late relapse [>3 years from complete remission (CR)] in acute lymphoblastic leukaemia (ALL), is unusual. Data from the MRC UKALLXII/ECOG E2993 trial are presented to evaluate the incidence and characteristics of late relapse in adult ALL. Of
Autor:
David I. Marks, Anthony V. Moorman, Lucy Chilton, Elisabeth Paietta, Amir Enshaie, Gordon DeWald, Christine J. Harrison, Adele K. Fielding, Letizia Foroni, Anthony H. Goldstone, Mark R. Litzow, Selina M. Luger, Andrew K. McMillan, Janis Racevskis, Jacob M. Rowe, Martin S. Tallman, Peter Wiernik, Hillard M. Lazarus
Publikováno v:
Haematologica, Vol 98, Iss 6 (2013)
The biology and outcome of adult t(4;11)(q21;q23)/MLL-AFF1 acute lymphoblastic leukemia are poorly understood. We describe the outcome and delineate prognostic factors and optimal post-remission therapy in 85 consecutive patients (median age 38 years
Externí odkaz:
https://doaj.org/article/e001fb0cab064bd3a4369c1e67f8e80a
Autor:
Bella Patel, Keiren E. Kirkland, Richard Szydlo, Rachel M. Pearce, Richard E. Clark, Charles Craddock, Effie Liakopoulou, Adele K. Fielding, Stephen Mackinnon, Eduardo Olavarria, Mike N. Potter, Nigel H. Russell, Bronwen E. Shaw, Gordon Cook, Anthony H. Goldstone, David I. Marks
Publikováno v:
Haematologica, Vol 94, Iss 10 (2009)
Background Approximately 40% of adults with Philadelphia chromosome-negative acute lymphoblastic leukemia achieve long-term survival following unrelated donor hematopoietic stem cell transplantation in first complete remission but severe graft-versus
Externí odkaz:
https://doaj.org/article/93328acd56e145d09c6d8acdb3eb9c6c
Publikováno v:
Blood. 111(12)
We thank the correspondent and agree that the issue is important. We enclose [Table 1][1] of survival at 5 years in the subgroups requested by the correspondent, where standard risk (SR) and high risk (HR) refer to white cell count and lineage only.
Autor:
Phyllis A. Gimotty, Mark R. Litzow, Joel M. Gelfand, Selina M. Luger, Anthony H. Goldstone, Alison W. Loren, Adele K. Fielding, Hillard M. Lazarus, Elisabeth Paietta, Georgina Buck, Martin S. Tallman, Anita Kumar, David I. Marks, Jacob M. Rowe
Publikováno v:
American Journal of Hematology. 91:1107-1112
Adults with acute lymphoblastic leukemia (ALL) have a poorer prognosis than children due to a high risk of relapse. One explanation may be variable adherence to dose-intense chemotherapy. However, little is known about risk factors for delays in ther